Blood-brain barrier: from molecular mechanisms to intervention strategies

Project Information

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Grant agreement ID: 865176

DOI

10.3030/865176

EC signature date 19 March 2020

Start date 1 January 2021

End date 31 December 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 286 542,50

EU contribution

€ 2 286 542,50

Coordinated by

UNIVERSITE LIBRE DE BRUXELLES
Belgium

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Engineered Wnt7a ligands rescue blood–brain barrier and cognitive deficits in a COVID-19 mouse model

Author(s): Troy N Trevino, Avital B Fogel, Guliz Otkiran, Seshadri B Niladhuri, Mark A Sanborn, Jacob Class, Ali A Almousawi, Benoit Vanhollebeke, Leon M Tai, Jalees Rehman, Justin M Richner, Sarah E Lutz
Published in: Brain, Issue 147, 2024, Page(s) 1636-1643, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awae031

The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish

Author(s): Alexandra Veloso, Anouk Bleuart, Louise Conrard, Tanguy Orban, Jonathan Bruyr, Pauline Cabochette, Raoul F. V. Germano, Giel Schevenels, Alice Bernard, Egor Zindy, Sofie Demeyer, Benoit Vanhollebeke, Franck Dequiedt, Maud Martin
Published in: BMC Biology, Issue 22, 2024, ISSN 1741-7007
Publisher: BioMed Central
DOI: 10.1186/s12915-024-01850-z

Reversal of cerebrovascular anomalies in a zebrafish model of vein of Galen aneurysm

Author(s): Edwige Martin-Valiente, Yao Du, Chloé Goemans, Michelle America, Egor Zindy, Myckel Adam, Benoit Scheid, Miikka Vikkula, Boris Lubicz, Benoit Vanhollebeke, Nicolas Baeyens
Published in: Nature Cardiovascular Research, Issue 4, 2025, Page(s) 773-789, ISSN 2731-0590
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s44161-025-00659-5

Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders

Author(s): Martin, Maud ;Vermeiren, Simon ;Bostaille, Naguissa ;Eubelen, Marie ;Spitzer, Daniel;Vermeersch, Marjorie ;Profaci, Caterina CP;Pozuelo Fernandez, Elisa ;Toussay, Xavier;Raman-Nair, Joanna;Tebabi, Patricia ;America, Michelle ;De Groote, Aurélie ;Sanderson, Leslie ;Cabochette, Pauline ;Freitas Vale Germano, Raoul ;Torres, David ;Boutry, Sébastien ;de Kerchove d'Exaerde, Alban ;Bellefroid, Eric ;P
Published in: Science, Issue 375, 2022, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abm4459

A brain-specific angiogenic mechanism enabled by tip cell specialization

Author(s): Giel Schevenels, Pauline Cabochette, Michelle America, Arnaud Vandenborne, Line De Grande, Stefan Guenther, Liqun He, Marc Dieu, Basile Christou, Marjorie Vermeersch, Raoul F. V. Germano, David Perez-Morga, Patricia Renard, Maud Martin, Michael Vanlandewijck, Christer Betsholtz, Benoit Vanhollebeke
Published in: Nature, Issue 628, 2024, Page(s) 863-871, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-024-07283-6

An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates

Author(s): Michelle America, Naguissa Bostaille, Marie Eubelen, Maud Martin, Didier Y.R. Stainier, Benoit Vanhollebeke
Published in: Cell reports, Issue 39, 9, 2022, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2022.110902