Deliverables
Description of the ORGANTRANS webpage that will be prepared in the first months of the project
The definition of the dissemination and communication strategy and tools to be used during the life of the project All possible dissemination routes for the obtained results will be identified and used during the whole course of the project
Sensor for the monitoring of dissolved oxygenReport describing the performances of the oxygen sensing system composed of sensor and reader The working range will be 1 to 21 O2 with an accuracy of 05 O2 and precision of 05
Protocol for the large-scale production of liver organoidsPublication of an optimised SOP for largescale expansion of organoids cultured in spinning bioreactors
Six established and fully characterized individual hepatic organoid linesCharacterisation of the organoid lines with respect to stem cell characteristics and differentiation potential will be published
Upscaling from research to medical Sphericalplate 5DUpscaling takes place by changing the Sphericalplate 5D research plate to the Sphericalplate 5D medical platform and assures the biological integrity of the cultivated organoids
Publications
Author(s):
Kerstin Schneeberger, Natalia Sánchez‐Romero, Shicheng Ye, Frank G. Steenbeek, Loes A. Oosterhoff, Iris Pla Palacin, Chen Chen, Monique E. Wolferen, Gilles Tienderen, Ruby Lieshout, Haaike Colemonts‐Vroninks, Imre Schene, Ruurdtje Hoekstra, Monique M.A. Verstegen, Luc J.W. Laan, Louis C. Penning, Sabine A. Fuchs, Hans Clevers, Joery De Kock, Pedro M. Baptista, Bart Spee
Published in:
Hepatology, Issue 72/1, 2020, Page(s) 257-270, ISSN 0270-9139
Publisher:
John Wiley & Sons Inc.
DOI:
10.1002/hep.31037
Author(s):
Sitara Vedaraman, Dominik Bernhagen, Tamas Haraszti, Christopher Licht, Arturo Castro Nava, Abdolrahman Omidinia Anarkoli, Peter Timmerman, Laura De Laporte
Published in:
Biomaterials Science, Issue 9/12, 2021, Page(s) 4329-4342, ISSN 2047-4830
Publisher:
Royal Society of Chemistry
DOI:
10.1039/d0bm02051f
Author(s):
Daniela F. Duarte Campos, Laura De Laporte
Published in:
Advanced Healthcare Materials, Issue 10/2, 2021, Page(s) 2001253, ISSN 2192-2640
Publisher:
John Wiley and Sons Ltd
DOI:
10.1002/adhm.202001253
Author(s):
Ary Marsee, Floris J.M. Roos, Monique M.A. Verstegen, Helmuth Gehart, Eelco de Koning, Frédéric Lemaigre, Stuart J. Forbes, Weng Chuan Peng, Meritxell Huch, Takanori Takebe, Ludovic Vallier, Hans Clevers, Luc J.W. van der Laan, Bart Spee, Ary Marsee, Floris Roos, Monique Verstegen, Hans Clevers, Ludovic Vallier, Takanori Takebe, Meritxell Huch, Weng Chuan Peng, Stuart Forbes, Frédéric Lemaigre
Published in:
Cell Stem Cell, Issue 28/5, 2021, Page(s) 816-832, ISSN 1934-5909
Publisher:
Cell Press
DOI:
10.1016/j.stem.2021.04.005
Author(s):
Pacheco Blanco, Mariana; Horokhovatskyi, Yevhen; Saar, Kristin; Aldag, Kristin
Published in:
zenodo.org, Issue 2, 2023
Publisher:
zenodo.org
DOI:
10.5281/zenodo.8054785
Author(s):
Mariana Pacheco Blanco; Yevhen Horokhovatskyi; Kristin Aldag; Kristin Saar
Published in:
zenodo.org, Issue 6, 2023
Publisher:
zenodo.org
DOI:
10.5281/zenodo.7947747
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