Project description
Novel catheter-based lung-cancer treatment in the tradition of angioplasty and arthroscopy
Cancer treatments vary depending on the type, stage, and aggressiveness of the cancer as well as on co-morbidities. Lung cancer is typically treated with surgery to remove the cancer or chemotherapy or radiation therapy to kill the cancerous cells, but these treatments are hard on the patient and involve extended durations for recovery from the treatments themselves. The Irish company ENDOWAVE Ltd has developed a patented microwave device that can be fed through a catheter into a patient's airways to reach the tumour site. Microwave heating is used to kill cancerous cells in a single minimally invasive office procedure. EU funding of the ENDOWAVE project is helping the company develop the foundations required for commercialisation.
Objective
Lung cancer is the most common cause of cancer deaths in the EU and worldwide with more than 0.4M people diagnosed each year. It has a dismal 5 year survival rate of just 18% and worldwide someone dies of lung cancer every 30 seconds. The impact of the disease on public health is substantial with > 6M hospital admissions in Europe each year (>€18 billion in economic costs). Surgery has been shown to provide a curative solution, but only 20-30% of patients can undergo surgery due to co-morbidities.
ENDOWAVE have developed a pioneering device, designed to destroy the targeted tumour in a single, minimally invasive intervention. The patented technology uses a flexible catheter system, which can be navigated through the patient’s airway to deliver targeted microwave heating to the tumour. This will enable physicians provide a curative treatment that can be delivered in an outpatient setting, improving patient outcomes and reducing costs to healthcare system.
The global market opportunity for lung cancer exceeds €3.6 billion. This SME Phase 1 Instrument funding will enable ENDOWAVE to complete detailed feasibility and business planning activities that will provide a platform for commercialisation of the technology. This will enable ENDOWAVE to enter the market, where we forecast revenues of €60 million by Year 5 based on conservative market penetration forecasts. This project will lead to job generation within ENDOWAVE and the associated supply chain.
Ultimately, ENDOWAVE seeks to improve outcomes for lung cancer patients by providing a curative treatment, which can be delivered in a single minimally invasive procedure.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences health sciences public health
- medical and health sciences clinical medicine surgery
- medical and health sciences clinical medicine oncology lung cancer
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
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H2020-EU.3. - PRIORITY 'Societal challenges
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H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
D02D K18 Dublin
Ireland
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.