Hominin phyloproteomics for the Pleistocene: PalaeoPROteomics of Skeletal Parts for Evolutionary Research

Información del proyecto

PROSPER

Identificador del acuerdo de subvención: 948365

DOI

10.3030/948365

Fecha de la firma de la CE 6 Noviembre 2020

Fecha de inicio 1 Diciembre 2020

Fecha de finalización 30 Noviembre 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 499 995,00

Aportación de la UE

€ 1 499 995,00

Coordinado por

KOBENHAVNS UNIVERSITET
Denmark

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (28)

Digging deeper into ancient skeletal proteomes through consecutive digestion with multiple proteases

Autores: Zandra Fagernäs, Gaudry Troché, Jesper V. Olsen, Frido Welker
Publicado en: Journal of Proteomics, Edición 298, 2024, Página(s) 105143, ISSN 1874-3919
Editor: Elsevier BV
DOI: 10.1016/j.jprot.2024.105143

Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry.

Autores: Hajdinjak, M., Mafessoni, F., Skov, L., Vernot, B., Hübner, A., Fu, Q., Essel, E., Nagel, S., Nickel, B., Richter, J., Moldovan, O.T., Constantin, S., Endarova, E., Zahariev, N., Spasov, R., Welker, F., Smith, G.M., Sinet-Mathiot, V., Paskulin, L., Fewlass, H., Talamo, S., Rezek, Z., Sirakova, S., Sirakov, N., McPherron, S.P., Tsanova, T., Hublin, J.-J., Peter, B.M., Meyer, M., Skoglund, P., Kels
Publicado en: Nature, Edición 52, 2021, Página(s) 253-257, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-021-03335-3

A male Denisovan mandible from Pleistocene Taiwan

Autores: Takumi Tsutaya, Rikai Sawafuji, Alberto J. Taurozzi, Zandra Fagernäs, Ioannis Patramanis, Gaudry Troché, Meaghan Mackie, Takashi Gakuhari, Hiroki Oota, Cheng-Hsiu Tsai, Jesper V. Olsen, Yousuke Kaifu, Chun-Hsiang Chang, Enrico Cappellini, Frido Welker
Publicado en: Science, Edición 388, 2025, Página(s) 176-180, ISSN 0036-8075
Editor: American Association for the Advancement of Science
DOI: 10.1126/science.ads3888

Combining traceological analysis and ZooMS on Early Neolithic bone artefacts from the cave of Coro Trasito, NE Iberian Peninsula: Cervidae used equally to Caprinae

Autores: Jakob Hansen, Alejandro Sierra, Sergi Mata, Ermengol Gassiot Ballbè, Javier Rey Lanaspa, Frido Welker, Maria Saña Seguí, Ignacio Clemente Conte
Publicado en: PLOS ONE, Edición 19, 2024, Página(s) e0306448, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0306448

Towards a Deeper Integration of ZooMS and Zooarchaeology at Paleolithic Sites: Current Challenges and Future Directions

Autores: Geoff Smith, Karen Ruebens, Virginie Sinet-Mathiot, Frido Welker
Publicado en: Paleoanthropology, 2024, ISSN 1545-0031
Editor: Paleoanthropology Society & European Society for the study of Human Evolution
DOI: 10.48738/2024.iss2.1244

The name of the game: palaeoproteomics and radiocarbon dates further refine the presence and dispersal of caprines in eastern and southern Africa

Autores: Louise Le Meillour; Antoine Zazzo; Séverine Zirah; Olivier Tombret; Véronique Barriel; Kathryn W. Arthur; John W. Arthur; Jessie Cauliez; Louis Chaix; Matthew C. Curtis; Diane Gifford-Gonzalez; Imogen Gunn; Xavier Gutherz; Elisabeth Hildebrand; Lamya Khalidi; Marie Millet; Peter Mitchell; Jacqueline Studer; Emmanuelle Vila; Frido Welker; David Pleurdeau; Joséphine Lesur
Publicado en: Royal Society Open Science, 2023, ISSN 2054-5703
Editor: The Royal Society Publishing
DOI: 10.1098/rsos.231002

Identifying the unidentified fauna enhances insights into hominin subsistence strategies during the Middle to Upper Palaeolithic transition.

Autores: Sinet-Mathiot, V., Rendu, W., Steele, T.E., Spasov, R., Madelaine, S., Renou, S., Soulier, M.-C., Martisius, N.L., Aldeais, V., Endarova, E., Goldberg, P., McPherron, S., Rezek, Z., Sandgathe, D., Sirakov, N., Sirakova, S., Soressi, M., Tsanova, T., Turq, A., Hublin, J.-J., Welker, F., Smith, G.M.
Publicado en: Archaeological and Anthropological Sciences, 2023, ISSN 1866-9557
Editor: Springer Verlag
DOI: 10.1007/s12520-023-01830-4

Earliest modern human genomes constrain timing of Neanderthal admixture

Autores: Arev P. Sümer, Hélène Rougier, Vanessa Villalba-Mouco, Yilei Huang, Leonardo N. M. Iasi, Elena Essel, Alba Bossoms Mesa, Anja Furtwaengler, Stéphane Peyrégne, Cesare de Filippo, Adam B. Rohrlach, Federica Pierini, Fabrizio Mafessoni, Helen Fewlass, Elena I. Zavala, Dorothea Mylopotamitaki, Raffaela A. Bianco, Anna Schmidt, Julia Zorn, Birgit Nickel, Anna Patova, Cosimo Posth, Geoff M. Smith,
Publicado en: Nature, Edición 638, 2025, Página(s) 711-717, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-024-08420-x

A 41,500 year-old decorated ivory pendant from Stajnia Cave (Poland).

Autores: Sahra Talamo; Sahra Talamo; Mikołaj Urbanowski; Andrea Picin; Wioletta Nowaczewska; Antonino Vazzana; Marcin Binkowski; Silvia Cercatillo; Marcin Diakowski; Helen Fewlass; Adrian Marciszak; Dragana Paleček; Michael P. Richards; Christina M. Ryder; Virginie Sinet-Mathiot; Geoff M. Smith; Paweł Socha; Matt Sponheimer; Matt Sponheimer; Krzysztof Stefaniak; Frido Welker; Frido Welker; Hanna Winter;
Publicado en: Scientific Reports, 2021, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-021-01221-6

A multi-proxy approach to exploring Homo sapiens’ arrival, environments and adaptations in Southeast Asia.

Autores: Bacon, A.-M., Bourgon, N., Welker, F., Cappellini, E., Fiorillo, D., Tombret, O., Thi Mai Huong, N., Anh Tuan, N., Sayavonkhamdy, T., Souksavatdy, V., Sichanthongtip, P., Antoine, P.-O., Duringer, P., Ponche, J.-L., Westaway, K., Joannes-Boyau, R., Boesch, Q., Suzzoni, E., Frangeul, S., Patole-Edoumba, E., Zachwieja, A., Shackelford, L., Demeter, F., Hublin, J.-J., Dufour, É.
Publicado en: Scientific Reports, 2021, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-021-99931-4

Early Holocene preservation differences between cortical and trabecular bone proteomes

Autores: Ragnheiður Diljá Ásmundsdóttir, Jakob Hansen, Zandra Fagernäs, Gaudry Troché, Jesper V. Olsen, Maria Saña Seguí, Frido Welker
Publicado en: Journal of Archaeological Science: Reports, Edición 57, 2025, Página(s) 104643, ISSN 2352-409X
Editor: Elsevier BV
DOI: 10.1016/j.jasrep.2024.104643

The effect of eraser sampling for proteomic analysis on Palaeolithic bone surface microtopography

Autores: Virginie Sinet-Mathiot; Naomi L. Martisius; Ellen Schulz-Kornas; Adam van Casteren; Tsenka R. Tsanova; Nikolay Sirakov; Rosen Spasov; Frido Welker; Geoff M. Smith; Jean-Jacques Hublin
Publicado en: Scientific Reports, 2021, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-021-02823-w

A Middle Pleistocene Denisovan molar from the Annamite Chain of northern Laos.

Autores: Demeter, F., Zanolli, C., Westaway, K.E., Joannes-Boyau, R., Duringer, P., Morley, M.W., Welker, F., Rüther, P.L., Skinner, M.M., McColl, H., Gaunitz, C., Vinner, L., Dunn, T.E., Olsen, J.V., Sikora, M., Ponche, J.-L., Suzzoni, E., Frangeul, S., Boesch, Q., Antoine, P.-O., Pan, L., Xing, S., Zhao, J.-X., Bailey, R.M., Boualaphane, S., Sichanthongtip, P., Sihanam, D., Patole-Edoumba, E., Aubaile,
Publicado en: Nature Communications, Edición 52, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-29923-z

Assessing the validity of a calcifying oral biofilm model as a suitable proxy for dental calculus

Autores: Bjørn Peare Bartholdy, Irina M. Velsko, Shira Gur-Arieh, Zandra Fagernäs, Christina Warinner, Amanda G. Henry
Publicado en: Open Research Europe, Edición 5, 2025, Página(s) 96, ISSN 2732-5121
Editor: F1000 Research Ltd
DOI: 10.12688/openreseurope.19129.1

Using ZooMS to assess archaeozoological insights and unravel human subsistence behaviour at La Viña rock shelter (northern Iberia)

Autores: Leire Torres-Iglesias, Ana B. Marín-Arroyo, Frido Welker, Marco de la Rasilla
Publicado en: Journal of Archaeological Science, Edición 161, 2025, Página(s) 105904, ISSN 0305-4403
Editor: Academic Press
DOI: 10.1016/j.jas.2023.105904

Homo sapiens reached the higher latitudes of Europe by 45,000 years ago

Autores: Dorothea Mylopotamitaki, Marcel Weiss, Helen Fewlass, Elena Irene Zavala, Hélène Rougier, Arev Pelin Sümer, Mateja Hajdinjak, Geoff M. Smith, Karen Ruebens, Virginie Sinet-Mathiot, Sarah Pederzani, Elena Essel, Florian S. Harking, Huan Xia, Jakob Hansen, André Kirchner, Tobias Lauer, Mareike Stahlschmidt, Michael Hein, Sahra Talamo, Lukas Wacker, Harald Meller, Holger Dietl, Jörg Orschiedt, J
Publicado en: Nature, Edición 626, 2024, Página(s) 341-346, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-023-06923-7

Neanderthal subsistence, taphonomy and chronology at Salzgitter-Lebenstedt (Germany): a multifaceted analysis of morphologically unidentifiable bone

Autores: Ruebens, K., Smith, G.M., Fewlass, H., Sinet-Mathiot, V., Hublin, J.-J., Welker, F.
Publicado en: Journal of Quaternary Science, Edición 8, 2023, ISSN 0267-8179
Editor: John Wiley & Sons Inc.
DOI: 10.1002/jqs.3499

Increasing sustainability in palaeoproteomics by optimizing digestion times for large-scale archaeological bone analyses

Autores: Louise Le Meillour, Virginie Sinet-Mathiot, Ragnheiður Diljá Ásmundsdóttir, Jakob Hansen, Dorothea Mylopotamitaki, Gaudry Troché, Huan Xia, Jorsua Herrera Bethencourt, Karen Ruebens, Geoff M. Smith, Zandra Fagernäs, Frido Welker
Publicado en: iScience, Edición 27, 2024, Página(s) 109432, ISSN 2589-0042
Editor: Elsevier BV
DOI: 10.1016/j.isci.2024.109432

The ecology, subsistence and diet of ~45,000-year-old Homo sapiens at Ilsenhöhle in Ranis, Germany

Autores: Geoff M. Smith, Karen Ruebens, Elena Irene Zavala, Virginie Sinet-Mathiot, Helen Fewlass, Sarah Pederzani, Klervia Jaouen, Dorothea Mylopotamitaki, Kate Britton, Hélène Rougier, Mareike Stahlschmidt, Matthias Meyer, Harald Meller, Holger Dietl, Jörg Orschiedt, Johannes Krause, Tim Schüler, Shannon P. McPherron, Marcel Weiss, Jean-Jacques Hublin, Frido Welker
Publicado en: Nature Ecology & Evolution, Edición 8, 2024, Página(s) 564-577, ISSN 2397-334X
Editor: Springer Science and Business Media LLC
DOI: 10.1038/s41559-023-02303-6

Middle and Late Pleistocene Denisovan subsistence at Baishiya Karst Cave

Autores: Huan Xia, Dongju Zhang, Jian Wang, Zandra Fagernäs, Ting Li, Yuanxin Li, Juanting Yao, Dongpeng Lin, Gaudry Troché, Geoff M. Smith, Xiaoshan Chen, Ting Cheng, Xuke Shen, Yuanyuan Han, Jesper V. Olsen, Zhongwei Shen, Zhiqi Pei, Jean-Jacques Hublin, Fahu Chen, Frido Welker
Publicado en: Nature, Edición 632, 2024, Página(s) 108-113, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-024-07612-9

Deep-time phylogenetic inference by paleoproteomic analysis of dental enamel

Autores: Alberto J. Taurozzi, Patrick L. Rüther, Ioannis Patramanis, Claire Koenig, Ryan Sinclair Paterson, Palesa P. Madupe, Florian Simon Harking, Frido Welker, Meaghan Mackie, Jazmín Ramos-Madrigal, Jesper V. Olsen, Enrico Cappellini
Publicado en: Nature Protocols, Edición 19, 2024, Página(s) 2085-2116, ISSN 1754-2189
Editor: Nature Publishing Group
DOI: 10.1038/s41596-024-00975-3

Comparing extraction method efficiency for high-throughput palaeoproteomics bone species identification

Autores: Mylopotamitaki, D., Harking, F.S., Taurozzi, A.J., Fagernäs, Z., Godinho, R.M., Smith, G.M., Weiss, M., Schüler, T., McPherron, S.P., Meller, H., Cascalheira, J., Bicho, N., Olsen, J.V., Hublin, J.-J., Welker, F.
Publicado en: Scientific Reports, 2023, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-023-44885-y

A Comparative Study of Commercially Available, Minimally Invasive, Sampling Methods on Early Neolithic Humeri Analysed Via Palaeoproteomics

Autores: Jakob Hansen, Joannes Dekker, Gaudry Trouché, Zandra Fagernäs, Jesper Velgaard Olsen, Maria Saña, Frido Welker
Publicado en: Journal of Archaeological Science, 2024, ISSN 1095-9238
Editor: Elsevier
DOI: 10.2139/ssrn.4771584

Spectra without stories: reporting 94% dark and unidentified ancient proteomes

Autores: Yun Chiang, Frido Welker, Matthew James Collins
Publicado en: Open Research Europe, Edición 4, 2024, Página(s) 71, ISSN 2732-5121
Editor: F1000 Research Ltd
DOI: 10.12688/openreseurope.17225.1

Palaeoproteomic identification of a whale bone tool from Bronze Age Heiloo, the Netherlands

Autores: Joannes A. A. Dekker, Dorothea Mylopotamitaki, Annemieke Verbaas, Virginie Sinet-Mathiot, Samantha Presslee, Morgan L. McCarthy, Morten Tange Olsen, Jesper V. Olsen, Youri van den Hurk, Joris Brattinga, Frido Welker
Publicado en: Peer Community Journal, Edición 4, 2024, ISSN 2804-3871
Editor: Peer Community In
DOI: 10.24072/pcjournal.451

The Late Middle Palaeolithic Occupation of Abri du Maras (Layer 1, Neronian, Southeast France):Integrating Lithic Analyses, ZooMS and Radiocarbon Dating to Reconstruct Neanderthal Hunting Behaviour

Autores: Karen Ruebens; Virginie Sinet-Mathiot; Sahra Talamo; Geoff M. Smith; Frido Welker; Jean-Jacques Hublin; Shannon P. McPherron
Publicado en: Journal of Paleolithic Archaeology, Edición 1, 2022, ISSN 2520-8217
Editor: Nature Springer
DOI: 10.1007/s41982-022-00113-z

Ancient biomolecular analysis of 39 mammoth individuals from Kostenki 11-Ia elucidates Upper Palaeolithic human resource use

Autores: Alba Rey-Iglesia, Alexander J.E. Pryor, Deon de Jager, Tess Wilson, Mathew A. Teeter, Ashot Margaryan, Ruslan Khaskhanov, Louise Le Meillour, Gaudry Troché, Frido Welker, Paul Szpak, Alexandr E. Dudin, Eline D. Lorenzen
Publicado en: Quaternary Environments and Humans, Edición 3, 2025, Página(s) 100049, ISSN 2950-2365
Editor: Elsevier BV
DOI: 10.1016/j.qeh.2024.100049

SPIN enables high throughput species identification of archaeological bone by proteomics

Autores: Rüther, P.L., Husic, I.M., Bangsgaard, P., Gregersen, K.M., Pantmann, P., Carvalho, M., Godinho, R.M., Friedl, L., Cascalheira, J., Taurozzi, A.J., Jørkov, M.L.S., Benedetti, M.M., Haws, J., Bicho, N., Welker, F., Cappellini, E., Olsen, J.V.
Publicado en: Nature Communications, Edición 52, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-30097-x