Hominin phyloproteomics for the Pleistocene: PalaeoPROteomics of Skeletal Parts for Evolutionary Research

Informazioni relative al progetto

PROSPER

ID dell’accordo di sovvenzione: 948365

DOI

10.3030/948365

Data della firma CE 6 Novembre 2020

Data di avvio 1 Dicembre 2020

Data di completamento 30 Novembre 2025

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 499 995,00

Contributo UE

€ 1 499 995,00

Coordinato da

KOBENHAVNS UNIVERSITET
Denmark

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (28)

Digging deeper into ancient skeletal proteomes through consecutive digestion with multiple proteases

Autori: Zandra Fagernäs, Gaudry Troché, Jesper V. Olsen, Frido Welker
Pubblicato in: Journal of Proteomics, Numero 298, 2024, Pagina/e 105143, ISSN 1874-3919
Editore: Elsevier BV
DOI: 10.1016/j.jprot.2024.105143

Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry.

Autori: Hajdinjak, M., Mafessoni, F., Skov, L., Vernot, B., Hübner, A., Fu, Q., Essel, E., Nagel, S., Nickel, B., Richter, J., Moldovan, O.T., Constantin, S., Endarova, E., Zahariev, N., Spasov, R., Welker, F., Smith, G.M., Sinet-Mathiot, V., Paskulin, L., Fewlass, H., Talamo, S., Rezek, Z., Sirakova, S., Sirakov, N., McPherron, S.P., Tsanova, T., Hublin, J.-J., Peter, B.M., Meyer, M., Skoglund, P., Kels
Pubblicato in: Nature, Numero 52, 2021, Pagina/e 253-257, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-021-03335-3

A male Denisovan mandible from Pleistocene Taiwan

Autori: Takumi Tsutaya, Rikai Sawafuji, Alberto J. Taurozzi, Zandra Fagernäs, Ioannis Patramanis, Gaudry Troché, Meaghan Mackie, Takashi Gakuhari, Hiroki Oota, Cheng-Hsiu Tsai, Jesper V. Olsen, Yousuke Kaifu, Chun-Hsiang Chang, Enrico Cappellini, Frido Welker
Pubblicato in: Science, Numero 388, 2025, Pagina/e 176-180, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.ads3888

Combining traceological analysis and ZooMS on Early Neolithic bone artefacts from the cave of Coro Trasito, NE Iberian Peninsula: Cervidae used equally to Caprinae

Autori: Jakob Hansen, Alejandro Sierra, Sergi Mata, Ermengol Gassiot Ballbè, Javier Rey Lanaspa, Frido Welker, Maria Saña Seguí, Ignacio Clemente Conte
Pubblicato in: PLOS ONE, Numero 19, 2024, Pagina/e e0306448, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0306448

Towards a Deeper Integration of ZooMS and Zooarchaeology at Paleolithic Sites: Current Challenges and Future Directions

Autori: Geoff Smith, Karen Ruebens, Virginie Sinet-Mathiot, Frido Welker
Pubblicato in: Paleoanthropology, 2024, ISSN 1545-0031
Editore: Paleoanthropology Society & European Society for the study of Human Evolution
DOI: 10.48738/2024.iss2.1244

The name of the game: palaeoproteomics and radiocarbon dates further refine the presence and dispersal of caprines in eastern and southern Africa

Autori: Louise Le Meillour; Antoine Zazzo; Séverine Zirah; Olivier Tombret; Véronique Barriel; Kathryn W. Arthur; John W. Arthur; Jessie Cauliez; Louis Chaix; Matthew C. Curtis; Diane Gifford-Gonzalez; Imogen Gunn; Xavier Gutherz; Elisabeth Hildebrand; Lamya Khalidi; Marie Millet; Peter Mitchell; Jacqueline Studer; Emmanuelle Vila; Frido Welker; David Pleurdeau; Joséphine Lesur
Pubblicato in: Royal Society Open Science, 2023, ISSN 2054-5703
Editore: The Royal Society Publishing
DOI: 10.1098/rsos.231002

Identifying the unidentified fauna enhances insights into hominin subsistence strategies during the Middle to Upper Palaeolithic transition.

Autori: Sinet-Mathiot, V., Rendu, W., Steele, T.E., Spasov, R., Madelaine, S., Renou, S., Soulier, M.-C., Martisius, N.L., Aldeais, V., Endarova, E., Goldberg, P., McPherron, S., Rezek, Z., Sandgathe, D., Sirakov, N., Sirakova, S., Soressi, M., Tsanova, T., Turq, A., Hublin, J.-J., Welker, F., Smith, G.M.
Pubblicato in: Archaeological and Anthropological Sciences, 2023, ISSN 1866-9557
Editore: Springer Verlag
DOI: 10.1007/s12520-023-01830-4

Earliest modern human genomes constrain timing of Neanderthal admixture

Autori: Arev P. Sümer, Hélène Rougier, Vanessa Villalba-Mouco, Yilei Huang, Leonardo N. M. Iasi, Elena Essel, Alba Bossoms Mesa, Anja Furtwaengler, Stéphane Peyrégne, Cesare de Filippo, Adam B. Rohrlach, Federica Pierini, Fabrizio Mafessoni, Helen Fewlass, Elena I. Zavala, Dorothea Mylopotamitaki, Raffaela A. Bianco, Anna Schmidt, Julia Zorn, Birgit Nickel, Anna Patova, Cosimo Posth, Geoff M. Smith,
Pubblicato in: Nature, Numero 638, 2025, Pagina/e 711-717, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-024-08420-x

A 41,500 year-old decorated ivory pendant from Stajnia Cave (Poland).

Autori: Sahra Talamo; Sahra Talamo; Mikołaj Urbanowski; Andrea Picin; Wioletta Nowaczewska; Antonino Vazzana; Marcin Binkowski; Silvia Cercatillo; Marcin Diakowski; Helen Fewlass; Adrian Marciszak; Dragana Paleček; Michael P. Richards; Christina M. Ryder; Virginie Sinet-Mathiot; Geoff M. Smith; Paweł Socha; Matt Sponheimer; Matt Sponheimer; Krzysztof Stefaniak; Frido Welker; Frido Welker; Hanna Winter;
Pubblicato in: Scientific Reports, 2021, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-021-01221-6

A multi-proxy approach to exploring Homo sapiens’ arrival, environments and adaptations in Southeast Asia.

Autori: Bacon, A.-M., Bourgon, N., Welker, F., Cappellini, E., Fiorillo, D., Tombret, O., Thi Mai Huong, N., Anh Tuan, N., Sayavonkhamdy, T., Souksavatdy, V., Sichanthongtip, P., Antoine, P.-O., Duringer, P., Ponche, J.-L., Westaway, K., Joannes-Boyau, R., Boesch, Q., Suzzoni, E., Frangeul, S., Patole-Edoumba, E., Zachwieja, A., Shackelford, L., Demeter, F., Hublin, J.-J., Dufour, É.
Pubblicato in: Scientific Reports, 2021, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-021-99931-4

Early Holocene preservation differences between cortical and trabecular bone proteomes

Autori: Ragnheiður Diljá Ásmundsdóttir, Jakob Hansen, Zandra Fagernäs, Gaudry Troché, Jesper V. Olsen, Maria Saña Seguí, Frido Welker
Pubblicato in: Journal of Archaeological Science: Reports, Numero 57, 2025, Pagina/e 104643, ISSN 2352-409X
Editore: Elsevier BV
DOI: 10.1016/j.jasrep.2024.104643

The effect of eraser sampling for proteomic analysis on Palaeolithic bone surface microtopography

Autori: Virginie Sinet-Mathiot; Naomi L. Martisius; Ellen Schulz-Kornas; Adam van Casteren; Tsenka R. Tsanova; Nikolay Sirakov; Rosen Spasov; Frido Welker; Geoff M. Smith; Jean-Jacques Hublin
Pubblicato in: Scientific Reports, 2021, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-021-02823-w

A Middle Pleistocene Denisovan molar from the Annamite Chain of northern Laos.

Autori: Demeter, F., Zanolli, C., Westaway, K.E., Joannes-Boyau, R., Duringer, P., Morley, M.W., Welker, F., Rüther, P.L., Skinner, M.M., McColl, H., Gaunitz, C., Vinner, L., Dunn, T.E., Olsen, J.V., Sikora, M., Ponche, J.-L., Suzzoni, E., Frangeul, S., Boesch, Q., Antoine, P.-O., Pan, L., Xing, S., Zhao, J.-X., Bailey, R.M., Boualaphane, S., Sichanthongtip, P., Sihanam, D., Patole-Edoumba, E., Aubaile,
Pubblicato in: Nature Communications, Numero 52, 2022, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-022-29923-z

Assessing the validity of a calcifying oral biofilm model as a suitable proxy for dental calculus

Autori: Bjørn Peare Bartholdy, Irina M. Velsko, Shira Gur-Arieh, Zandra Fagernäs, Christina Warinner, Amanda G. Henry
Pubblicato in: Open Research Europe, Numero 5, 2025, Pagina/e 96, ISSN 2732-5121
Editore: F1000 Research Ltd
DOI: 10.12688/openreseurope.19129.1

Using ZooMS to assess archaeozoological insights and unravel human subsistence behaviour at La Viña rock shelter (northern Iberia)

Autori: Leire Torres-Iglesias, Ana B. Marín-Arroyo, Frido Welker, Marco de la Rasilla
Pubblicato in: Journal of Archaeological Science, Numero 161, 2025, Pagina/e 105904, ISSN 0305-4403
Editore: Academic Press
DOI: 10.1016/j.jas.2023.105904

Homo sapiens reached the higher latitudes of Europe by 45,000 years ago

Autori: Dorothea Mylopotamitaki, Marcel Weiss, Helen Fewlass, Elena Irene Zavala, Hélène Rougier, Arev Pelin Sümer, Mateja Hajdinjak, Geoff M. Smith, Karen Ruebens, Virginie Sinet-Mathiot, Sarah Pederzani, Elena Essel, Florian S. Harking, Huan Xia, Jakob Hansen, André Kirchner, Tobias Lauer, Mareike Stahlschmidt, Michael Hein, Sahra Talamo, Lukas Wacker, Harald Meller, Holger Dietl, Jörg Orschiedt, J
Pubblicato in: Nature, Numero 626, 2024, Pagina/e 341-346, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-023-06923-7

Neanderthal subsistence, taphonomy and chronology at Salzgitter-Lebenstedt (Germany): a multifaceted analysis of morphologically unidentifiable bone

Autori: Ruebens, K., Smith, G.M., Fewlass, H., Sinet-Mathiot, V., Hublin, J.-J., Welker, F.
Pubblicato in: Journal of Quaternary Science, Numero 8, 2023, ISSN 0267-8179
Editore: John Wiley & Sons Inc.
DOI: 10.1002/jqs.3499

Increasing sustainability in palaeoproteomics by optimizing digestion times for large-scale archaeological bone analyses

Autori: Louise Le Meillour, Virginie Sinet-Mathiot, Ragnheiður Diljá Ásmundsdóttir, Jakob Hansen, Dorothea Mylopotamitaki, Gaudry Troché, Huan Xia, Jorsua Herrera Bethencourt, Karen Ruebens, Geoff M. Smith, Zandra Fagernäs, Frido Welker
Pubblicato in: iScience, Numero 27, 2024, Pagina/e 109432, ISSN 2589-0042
Editore: Elsevier BV
DOI: 10.1016/j.isci.2024.109432

The ecology, subsistence and diet of ~45,000-year-old Homo sapiens at Ilsenhöhle in Ranis, Germany

Autori: Geoff M. Smith, Karen Ruebens, Elena Irene Zavala, Virginie Sinet-Mathiot, Helen Fewlass, Sarah Pederzani, Klervia Jaouen, Dorothea Mylopotamitaki, Kate Britton, Hélène Rougier, Mareike Stahlschmidt, Matthias Meyer, Harald Meller, Holger Dietl, Jörg Orschiedt, Johannes Krause, Tim Schüler, Shannon P. McPherron, Marcel Weiss, Jean-Jacques Hublin, Frido Welker
Pubblicato in: Nature Ecology & Evolution, Numero 8, 2024, Pagina/e 564-577, ISSN 2397-334X
Editore: Springer Science and Business Media LLC
DOI: 10.1038/s41559-023-02303-6

Middle and Late Pleistocene Denisovan subsistence at Baishiya Karst Cave

Autori: Huan Xia, Dongju Zhang, Jian Wang, Zandra Fagernäs, Ting Li, Yuanxin Li, Juanting Yao, Dongpeng Lin, Gaudry Troché, Geoff M. Smith, Xiaoshan Chen, Ting Cheng, Xuke Shen, Yuanyuan Han, Jesper V. Olsen, Zhongwei Shen, Zhiqi Pei, Jean-Jacques Hublin, Fahu Chen, Frido Welker
Pubblicato in: Nature, Numero 632, 2024, Pagina/e 108-113, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-024-07612-9

Deep-time phylogenetic inference by paleoproteomic analysis of dental enamel

Autori: Alberto J. Taurozzi, Patrick L. Rüther, Ioannis Patramanis, Claire Koenig, Ryan Sinclair Paterson, Palesa P. Madupe, Florian Simon Harking, Frido Welker, Meaghan Mackie, Jazmín Ramos-Madrigal, Jesper V. Olsen, Enrico Cappellini
Pubblicato in: Nature Protocols, Numero 19, 2024, Pagina/e 2085-2116, ISSN 1754-2189
Editore: Nature Publishing Group
DOI: 10.1038/s41596-024-00975-3

Comparing extraction method efficiency for high-throughput palaeoproteomics bone species identification

Autori: Mylopotamitaki, D., Harking, F.S., Taurozzi, A.J., Fagernäs, Z., Godinho, R.M., Smith, G.M., Weiss, M., Schüler, T., McPherron, S.P., Meller, H., Cascalheira, J., Bicho, N., Olsen, J.V., Hublin, J.-J., Welker, F.
Pubblicato in: Scientific Reports, 2023, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-023-44885-y

A Comparative Study of Commercially Available, Minimally Invasive, Sampling Methods on Early Neolithic Humeri Analysed Via Palaeoproteomics

Autori: Jakob Hansen, Joannes Dekker, Gaudry Trouché, Zandra Fagernäs, Jesper Velgaard Olsen, Maria Saña, Frido Welker
Pubblicato in: Journal of Archaeological Science, 2024, ISSN 1095-9238
Editore: Elsevier
DOI: 10.2139/ssrn.4771584

Spectra without stories: reporting 94% dark and unidentified ancient proteomes

Autori: Yun Chiang, Frido Welker, Matthew James Collins
Pubblicato in: Open Research Europe, Numero 4, 2024, Pagina/e 71, ISSN 2732-5121
Editore: F1000 Research Ltd
DOI: 10.12688/openreseurope.17225.1

Palaeoproteomic identification of a whale bone tool from Bronze Age Heiloo, the Netherlands

Autori: Joannes A. A. Dekker, Dorothea Mylopotamitaki, Annemieke Verbaas, Virginie Sinet-Mathiot, Samantha Presslee, Morgan L. McCarthy, Morten Tange Olsen, Jesper V. Olsen, Youri van den Hurk, Joris Brattinga, Frido Welker
Pubblicato in: Peer Community Journal, Numero 4, 2024, ISSN 2804-3871
Editore: Peer Community In
DOI: 10.24072/pcjournal.451

The Late Middle Palaeolithic Occupation of Abri du Maras (Layer 1, Neronian, Southeast France):Integrating Lithic Analyses, ZooMS and Radiocarbon Dating to Reconstruct Neanderthal Hunting Behaviour

Autori: Karen Ruebens; Virginie Sinet-Mathiot; Sahra Talamo; Geoff M. Smith; Frido Welker; Jean-Jacques Hublin; Shannon P. McPherron
Pubblicato in: Journal of Paleolithic Archaeology, Numero 1, 2022, ISSN 2520-8217
Editore: Nature Springer
DOI: 10.1007/s41982-022-00113-z

Ancient biomolecular analysis of 39 mammoth individuals from Kostenki 11-Ia elucidates Upper Palaeolithic human resource use

Autori: Alba Rey-Iglesia, Alexander J.E. Pryor, Deon de Jager, Tess Wilson, Mathew A. Teeter, Ashot Margaryan, Ruslan Khaskhanov, Louise Le Meillour, Gaudry Troché, Frido Welker, Paul Szpak, Alexandr E. Dudin, Eline D. Lorenzen
Pubblicato in: Quaternary Environments and Humans, Numero 3, 2025, Pagina/e 100049, ISSN 2950-2365
Editore: Elsevier BV
DOI: 10.1016/j.qeh.2024.100049

SPIN enables high throughput species identification of archaeological bone by proteomics

Autori: Rüther, P.L., Husic, I.M., Bangsgaard, P., Gregersen, K.M., Pantmann, P., Carvalho, M., Godinho, R.M., Friedl, L., Cascalheira, J., Taurozzi, A.J., Jørkov, M.L.S., Benedetti, M.M., Haws, J., Bicho, N., Welker, F., Cappellini, E., Olsen, J.V.
Pubblicato in: Nature Communications, Numero 52, 2022, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-022-30097-x