Exploitable results Genetic modification of parvovirus Modification of the genomes of parvoviruses H-1 and MVM, attempting to make them suitable linear vectors, has resulted in: production of recombinant parvoviruses showing transduction specificity for oncogene-transformed cells and having potential for cancer gene therapy; programmed cell killing by means of inducible clones of parvoviral genes encoding nonstructural proteins; demonstration and unravelling of the oncolytic activity of parvoviruses, raising prospects of anticancer applications. È in corso la ricerca di dati su OpenAIRE... Si è verificato un errore durante la ricerca dei dati su OpenAIRE Nessun risultato disponibile
