Objective
Developing therapeutic strategies for Tees is of great public concern, especially since the advent of variant CJD. We will examine, in a comprehensive and integrate-ed manner, novel candidate drugs targeting different key events in infected pathogen-sis. We will identify compounds that disrupt the structure of prisons (reducing infectivity), inhibit Preps production &/or prevent Induced-induced neurotoxicity. The compounds will then be tested for their ability to inhibit infected replication in lymphoid tissues, block neuroinvasion, inhibit establishment of infection in the CNS &/or retard pathological changes in the brain that lead to clinical disease. These objectives will be attained through combined high throughput in vitro screening systems & defined animal models. Insights into mechanisms of infected disease pathogenesis will be obtained. The outcome will be named compounds that could be used to treat TSE disease in man or inactivate infectivity in biomedical products.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
G61 1QH GLASGOW
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.