A European-wide foundation to accelerate Data-driven Cancer Research

Projektinformationen

EOSC4Cancer

ID Finanzhilfevereinbarung: 101058427

DOI

10.3030/101058427

Projekt abgeschlossen

EK-Unterschriftsdatum 9 Juni 2022

Startdatum 1 September 2022

Enddatum 31 Mai 2025

Finanziert unter

• Research infrastructures

Gesamtkosten

€ 7 814 549,51

EU-Beitrag

€ 7 814 549,00

Koordiniert durch

BARCELONA SUPERCOMPUTING CENTER CENTRO NACIONAL DE SUPERCOMPUTACION
Spain

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Documents, reports (14)

Synthetic cohort status

Descriptions, documentation, and links to the synthetic cohorts generated by the project.

Policy Brief

This Policy Brief should include specific information about the project results and outcomes and the links with the other Research Infrastructures and the European Open Science Cloud -EOSC family, including links to any relevant policy documents and deliverables. The information gathered from the projects through these Policy briefs will inform future policy and programme developments by EU policymakers.To be delivered together with the First Periodic Report.

Summary report on use-cases

Final report on use-cases 1-5 describing the results, lessons learned, and recommendations for future projects in the Cancer Mission

European landscape and stakeholder engagement report

Report on engagement with relevant initiatives and stakeholders

Report on sustainability plans

Sustainability plans for project outputs

Publication of live Outreach and Communications Strategy

Report outlining the project strategy on communication to key stakeholders and the wider public

A guidance document for the EOSC4Cancer learning pathways

A document outlining learning pathways designed under EOSC4Cancer and connecting them to the identified EOSC roles and skills

Policy Brief Update

Update -- This Policy Brief should include specific information about the project results and outcomes and the links with the other Research Infrastructures and the European Open Science Cloud -EOSC family, including links to any relevant policy documents and deliverables. The information gathered from the projects through these Policy briefs will inform future policy and programme developments by EU policymakers.To be delivered together with the Second and Final Periodic Report.

Roadmap for EOSC support to a European Cancer Data Space

Long-term EOSC4Cancer service roadmap.

SOPs for minimal clinical, image and omics data exchange

A set of SOPs for minimal data exchange taking into account how cancer-related resources are stored, coded and made accessible in key resources identified via WP1.1

Survey-based report determining annotation and harmonization needs

Field survey report, minimum required data structure determined (Benchmark analysis determining annotation and harmonization needs across colorectal cancer research and clinical community).

Project Data Management Plan

Project data management plan following EC requirements and recommendations.

Courses portfolio, linked through the RDMkit Cancer View

A document outlining the key learning pathways defined under Task 5.2, and linked through the RDMkit Cancer View portal

Project Data Management Plan Update

Project data management plan – Final report

Demonstrators, pilots, prototypes (6)

Virtual Research Environment interoperability

Demonstrator of portals and analysis workflows interoperability.

Data access interoperability

A demonstrator covering the status of DUO and AAI interoperability across the data resources.

Reference Beacon implementation for EOSC4Cancer

Dedicated beacon instances are lighted for the relevant data sources needed by the use-cases. Report and demo

Integrated analysis of multiple data types

Portable cBioPortal implementation capable of integration of multiple federated data types

Data resources map

Living map of data resources including high level descriptors, accessprocedures and interfaces, and data use requirements.

Molecular Tumour Board Portal interoperability

Demonstrator of MTBP capabilities to integrate novel data types relevant for patient cohort

Websites, patent fillings, videos etc. (3)

First content of the RDMkit Cancer View

An active portal to be viewed (Have a first outline of the RDMkit Cancer View page).

Initial resource directory map

First catalogue instance ‘live’, including documentation, and resource links for implementations of standards

Final release of the RDMkit Cancer View

An active portal to be viewed (Final release of the RDMkit Cancer View page).

Veröffentlichungen

Peer reviewed articles (10)

Lessons Learned From European Health Data Projects With Cancer Use Cases: Implementation of Health Standards and Internet of Things Semantic Interoperability

Autoren: Amelie Gyrard, Somayeh Abedian, Philip Gribbon, George Manias, Rick van Nuland, Kurt Zatloukal, Irina Emilia Nicolae, Gabriel Danciu, Septimiu Nechifor, Luis Marti-Bonmati, Pedro Mallol, Stefano Dalmiani, Serge Autexier, Mario Jendrossek, Ioannis Avramidis, Eva Garcia Alvarez, Petr Holub, Ignacio Blanquer, Anna Boden, Rada Hussein
Veröffentlicht in: Journal of Medical Internet Research, Ausgabe 27, 2025, ISSN 1438-8871
Herausgeber: JMIR Publications Inc.
DOI: 10.2196/66273

Roadmap for a European cancer data management and precision medicine infrastructure

Autoren: Macha Nikolski, Eivind Hovig, Fatima Al-Shahrour, Niklas Blomberg, Serena Scollen, Alfonso Valencia, Gary Saunders
Veröffentlicht in: Nature Cancer, Ausgabe 5, 2024, ISSN 2662-1347
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1038/S43018-023-00717-6

Sharing data as machine-actionable objects using RO-Crate, Bioschemas and Signposting

Autoren: Stian Soiland-Reyes; Simone Leo; Leyla Jael Castro; Peter Sefton; Carole Goble
Veröffentlicht in: F1000, 2023
Herausgeber: ELIXIR
DOI: 10.7490/f1000research.1119431.1

Structure

Autoren: Schwalbe, Harald; Audergon, Pauline; Haley, Natalie; Amaro, Claudia Alen; Agirre, Jon; Baldus, Marc; Banci, Lucia; Baumeister, Wolfgang; Blackledge, Martin; Carazo, Jose Maria; Carugo, Kristina Djinovic; Celie, Patrick; Felli, Isabella; Hart, Darren J.; Hauß, Thomas; Lehtiö, Lari; Lindorff-Larsen, Kresten; Márquez, José; Matagne, André; Pierattelli, Roberta; Rosato, Antonio; Sobott, Frank; Sreeramulu, Sridhar; Steyaert, Jan; Sussman, Joel L.; Trantirek, Lukas; Weiss, Manfred S.; Wilmanns, Matthias
Veröffentlicht in: Structure, 2024, ISSN 0969-2126
Herausgeber: Cell Press
DOI: 10.1016/J.STR.2024.08.014

FAIR-IMPACT synergies with EOSC4Cancer

Autoren: Stian Soiland-Reyes; Carole Goble; Raquel Villodres Toledo; Romina Royo; Salvador Capella-Gutierrez
Veröffentlicht in: EOSC4CANCER, 2022
Herausgeber: Zenodo
DOI: 10.5281/zenodo.6771194

UNCAN.eu: Toward a European Federated Cancer Research Data Hub

Autoren: Boutros, Michael; Baumann, Michael; Bigas, Anna; Chaabane, Linda; Guérin, Julien; Habermann, Jens K.; Habermann, Jens K.; JOBARD, Aurélien; PELICCI, PIER GIUSEPPE; Stegle, Oliver; Tonon, Giovanni; valencia, alfonso; Winkler, Eva; BLANC, Patricia; De Maria, Ruggero; Medema, Rene H.; Nagy, Péter; Tabernero, Josep; Solary, Eric
Veröffentlicht in: Cancer Discovery, 2024, ISSN 2159-8290
Herausgeber: Cancer Discovery
DOI: 10.1158/2159-8290.CD-23-1111

OpenVariant: a toolkit to parse and operate multiple input file formats

Autoren: David Martínez-Millán, Federica Brando, Miguel L. Grau, Mònica Sánchez-Guixé, Carlos López-Elorduy, Iker Reyes-Salazar, Jordi Deu-Pons, Núria López-Bigas, Abel González-Pérez
Veröffentlicht in: Bioinformatics, Ausgabe 40, 2024, ISSN 1367-4811
Herausgeber: Oxford University Press (OUP)
DOI: 10.1093/BIOINFORMATICS/BTAE714

Identification of Clonal Hematopoiesis Driver Mutations through In Silico Saturation Mutagenesis

Autoren: Santiago Demajo; Joan E. Ramis-Zaldivar; Ferran Muiños; Miguel L. Grau; Maria Andrianova; Núria López-Bigas; Abel González-Pérez
Veröffentlicht in: Cancer Discovery, 2023, ISSN 1538-7445
Herausgeber: American Association for Cancer Research
DOI: 10.1101/2023.12.13.23299893

UNCAN.eu: Toward a European Federated Cancer Research Data Hub

Autoren: Michael Boutros, Michael Baumann, Anna Bigas, Linda Chaabane, Julien Guérin, Jens K. Habermann, Aurélien Jobard, Pier Giuseppe Pelicci, Oliver Stegle, Giovanni Tonon, Alfonso Valencia, Eva C. Winkler, Patricia Blanc, Ruggero De Maria, Rene H. Medema, Peter Nagy, Josep Tabernero, Eric Solary
Veröffentlicht in: Cancer Discovery, Ausgabe 14, 2024, ISSN 2159-8274
Herausgeber: American Association for Cancer Research (AACR)
DOI: 10.1158/2159-8290.CD-23-1111

TrialMatchAI: An End-to-End AI-powered Clinical Trial Recommendation System to Streamline Patient-to-Trial Matching

Autoren: Majd Abdallah, Sigve Nakken, Mariska Bierkens, Johanna Galvis, Alexis Groppi, Slim Karkar, Lana Meiqari, Maria Alexandra Rujano, Steve Canham, Rodrigo Dienstmann, Remond Fijneman, Eivind Hovig, Gerrit Meijer, Macha Nikolski
Veröffentlicht in: arxiv and submitted to Nature Communications, 2025, ISSN 2331-8422
Herausgeber: Arxiv
DOI: 10.48550/ARXIV.2505.08508

Other (18)

Kickoff meeting - EOSC4Cancer Network of key cancer data support professionals

Autoren: Celia W.G. van Gelder
Veröffentlicht in: EOSC4CANCER, 2023
Herausgeber: Zenodo
DOI: 10.5281/zenodo.8328995

Life Science Competence Centres: Open by Design

Autoren: David, Romain; Liaskos, Nektarios; Rybina, Arina; Arvanitidis, Christos; Bage, Anne-Sophie; Carvajal-Vallejos, Patricia K.; Das, Sudeep; De Pascalis, Francesca; Dörr, Dorothea; Exter, Katrina; Holub, Petr; Gurwitz, Kim Tamara; Liberante, Fabio; Lieutaud, Philippe; Lister, Allyson; Lopez, Joaquin; Madon, Bénédicte; Massimi, Marzia; Matteoni, Rafaele; Mîrza, Maria; Morgan, Sarah; Oezdemir, Bugra; Panagiotopoulou, Maria; Pavloudi, Christina; P. Melo, Ana M.; Sansone, Susanna-Assunta; Schwalbe, Harald; Serrano-Solano, Beatriz; Sorzano, Carlos Oscar; Urbinati, Emilio; Tang, Jing; Tedds, Jonathan; Saunders, Gary; Ewbank, Jonathan
Veröffentlicht in: 2025
Herausgeber: zenodo
DOI: 10.5281/ZENODO.15798751

EOSC4Cancer: Federated discovery for secondary use of cancer registry data

Autoren: Teresa García Lezana, Jordi Rambla, Jan Trallero, Rafael Marcos-Gragera, EU EOSC4Cancer Consortium
Veröffentlicht in: 2023
Herausgeber: ENCR Secretariat

EOSC4Cancer Project Presentation

Autoren: Capella-Gutierrez, Salvador; Valencia, Alfonso; Villodres Toledo, Raquel; Royo, Romina
Veröffentlicht in: 2023
Herausgeber: Zenodo
DOI: 10.5281/ZENODO.8256508

D1.2 Data access interoperability

Autoren: Sankar, Aravind; Keane, Thomas
Veröffentlicht in: 2025
Herausgeber: zenodo
DOI: 10.5281/ZENODO.15638952

D1.1 - Data Resources Map

Autoren: Swertz, Morris; Been, Gerieke; Hijmans, Brenda
Veröffentlicht in: 2023
DOI: 10.5281/ZENODO.10837116

D4.2 - Summary report on use cases

Autoren: Meijer, Gerrit; ambrosino, concetta; Carvalho, Beatriz; Hajduch, Marian; Fijneman, Remond; Bierkens, Mariska; Dienstmann, Rodrigo; Huijskens, Sophie; Boiten, Jan-Willem; tamborero, david; Bendova, Michaela; Navest, Robin
Veröffentlicht in: 2025
Herausgeber: Zenodo
DOI: 10.5281/ZENODO.15526959

TrialMatchAI: An End-to-End AI-powered Clinical Trial Recommendation System to Streamline Patient-to-Trial Matching

Autoren: Abdallah, Majd; Nakken, Sigve; Bierkens, Mariska; Galvis, Johanna; Groppi, Alexis; Karkar, Slim; Meiqari, Lana; Rujano, Maria Alexandra; Canham, Steve; Dienstmann, Rodrigo; Fijneman, Remond; Hovig, Eivind; Meijer, Gerrit; Nikolski, Macha
Veröffentlicht in: 2025
Herausgeber: arxiv
DOI: 10.48550/ARXIV.2505.08508

D2.2 - Analytical methods for data extraction, processing and sharing using biomedical images

Autoren: Navest, Robin; Chèneby, Jeanne; Achterberg, Hakim; Gammaraccio, Francesco; Longo, Dario
Veröffentlicht in: 2025
Herausgeber: zenodo
DOI: 10.5281/ZENODO.15704479

cBioPortal Presentation Slides

Autoren: EOSC4Cancer
Veröffentlicht in: EOSC4CANCER, 2023
Herausgeber: Zenodo
DOI: 10.5281/zenodo.8163342

cBioPortal image integration manual

Autoren: Navest, Robin; Birhanu, Mahlet; Horak, Jirka; Longo, Dario
Veröffentlicht in: 2025
DOI: 10.5281/ZENODO.14900295

D2.3 Survey-based report determining annotation and harmonization needs

Autoren: Hajduch, Marian; Sromova, Katerina; Capella-Gutierrez, Salvador; Royo, Romina
Veröffentlicht in: 2023
Herausgeber: Zenodo
DOI: 10.5281/ZENODO.10067295

D5.1 - A guidance document for the EOSC4Cancer learning pathway

Autoren: Psomopoulos, Fotis; Al-Shahrour, Fátima; van Gelder, Celia; Morgan, Sarah; Andrabi, Munazah; Majcen, Kurt; Schoots, Fieke
Veröffentlicht in: 2023
DOI: 10.5281/ZENODO.10200523

D7.6 - Updated EOSC Policy Brief

Autoren: EOSC4Cancer Consortium
Veröffentlicht in: 2025
Herausgeber: zenodo
DOI: 10.5281/ZENODO.16572770

Making EOSC Research Objects FAIR with RO-Crate: A common metadata overlay for EOSC repositories

Autoren: Justin Clark-Casey; Stian Soiland-Reyes
Veröffentlicht in: ELIXIR, 2022
Herausgeber: Zenodo
DOI: 10.5281/zenodo.7323301

D6.1 Publication of live Outreach and Communications Strategy

Autoren: Schulz, Carola; Hanafi, Mouaz; Firdous, Sabah; Stroetmann, Veli
Veröffentlicht in: 2023
DOI: 10.5281/ZENODO.10067313

D1.4 - Synthetic Cohort Status

Autoren: Capella, Salvador; Aguiló, Sergi; Vázquez, Miguel; Labarga, Alberto; Royo, Romina
Veröffentlicht in: 2024
Herausgeber: Zenodo
DOI: 10.5281/ZENODO.10847696

cBioPortal Presentation Slides

Autoren: EOSC4Cancer
Veröffentlicht in: EOSC4CANCER, 2023
Herausgeber: Zenodo
DOI: 10.5281/ZENODO.8163342

Conference proceedings (1)

Establishing the EOSC4Cancer Network of Experts

Autoren: Psomopoulos, Fotis; Al-Shahrour, Fátima; van Gelder, Celia
Veröffentlicht in: 2023
Herausgeber: Zenodo
DOI: 10.5281/ZENODO.8073708