Objective
The overlap between the neural substrates and processes underlying perception and memory makes it difficult to dissociate them, and the complexity of high-level visual processing further complicates this task. By leveraging large-scale electrophysiology, intracortical microstimulation, and artificial intelligence, I will disentangle the complex relationship between visual perception and memory in monkeys, and develop innovative techniques for steering the visual content of memories and dissociate sensations from perception.
First, I will record and manipulate the neural activity of the inferotemporal cortex (IT) and perirhinal cortex (PrC) in macaque monkeys to provide a comprehensive and systematic investigation of the neural mechanisms underlying visual perception and memory. Then, I will provide causal evidence on the role of conscious perception in shaping the visual content of memories, and the importance of the IT-PrC circuitry in this process. Furthermore, I will determine the threshold between visual perception and memory, testing the hypothesis that a subsets of neurons in PrC can elicit a sense of familiarity independently of any visual input. Finally, I will demonstrate how memory gates visual information to control behavior in a closed loop experiment, employing state-of-the-art wirelles recording and microstimulation in freely behaving monkeys.
SteerMEM has the potential to revolutionize our understanding of visual perception and memory, paving the way to significant advancements for both neuroscience and clinics. SteerMEM will test a groundbreaking approach to manipulate long-term visual memory in a controlled and quantifiable fashion, and test the long-term applicability of this approach in ecological conditions. Finally, SteerMEM will lay the ground for AI-powered microstimulaiton in cognitive cortical prostheses for the potential treatment of memory impairments, anxiety and post-traumatic stress disorder.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology
- medical and health sciences medical biotechnology implants
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC - HORIZON ERC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2025-STG
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
43121 PARMA
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.