Project description
Virtual Physiological Human
MD-Paedigree, which stands for Model-Driven European Paediatric Digital Repository (http://www.md-paedigree.eu), provides decision support to medical professionals wherever they treat their young patients. Through disease simulations, requiring the availability of high performance and supercomputer resources, MD-Paedigree improves the diagnostic precision of paediatricians and offers child-specific treatment choices for Europe’s children.
MD-Paedigree follows two previous highly successful projects, Health-e-Child (www.health-e-child.org) and Sim-e-Child (www.sim-e-child.org), making it possible to apply innovative diagnostic tools to routine clinical data. It provides three fundamental functionalities on top of those of an advanced Electronic Health Records registry:
1. similarity search, allowing clinicians to access “patients like mine” (and finding decision support for optimal treatment also based on comparative outcome analysis), and allowing patients to get in touch with “patients exactly like me”
2. model-based patient-specific simulation and prediction
3. patient-specific clinical workflows.
Using MD-Paedigree, doctors can select a highly individualised treatment option and receive on-the-spot support in predicting the likely outcome of such treatments based on each patient’s personal medical data. This leads us into a future where child healthcare will become more effective, more personalised, and even more affordable.
MD-Paedigree is a clinically-led VPH project that addresses both the first and the second actions of part B of Objective ICT-2011.5.2:1. it enhances existing disease models stemming from former EC-funded research (Health-e-Child and Sim-e-Child) and from industry and academia, by developing robust and reusable multi-scale models for more predictive, individualised, effective and safer healthcare in several disease areas;2. it builds on the eHealth platform already developed for Health-e-Child and Sim-e-Child to establish a worldwide advanced paediatric digital repository.Integrating the point of care through state-of-the-art and fast response interfaces, MD-Paedigree services a broad range of off-the-shelf models and simulations to support physicians and clinical researchers in their daily work. MD-Paedigree vertically integrates data, information and knowledge of incoming patients, in participating hospitals from across Europe and the USA, and provides innovative tools to define new workflows of models towards personalised predictive medicine. Conceived of as a part of the "VPH Infostructure" described in the ARGOS, MD-Paedigree encompasses a set of services for storage, sharing, similarity search, outcome analysis, risk stratification, and personalised decision support in paediatrics within its innovative model-driven data and workflow-based digital repository. As a specific implementation of the VPH-Share project, MD-Paedigree fully interoperates with it. It has the ambition to be the dominant tool within its purview. MD-Paedigree integrates methodological approaches from the targeted specialties and consequently analyzes biomedical data derived from a multiplicity of heterogeneous sources (from clinical, genetic and metagenomic analysis, to MRI and US image analytics, to haemodynamics, to real-time processing of musculoskeletal parameters and fibres biomechanical data, and others), as well as specialised biomechanical and imaging VPH simulation models.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences health care services eHealth
- medical and health sciences clinical medicine paediatrics
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Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-ICT-2011-9
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Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
00165 Roma
Italy
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Participants (25)
3000 LEUVEN
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2800 Delemont
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Participation ended
80333 MUNCHEN
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91052 Erlangen
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80686 MUNCHEN
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53111 BONN
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13353 Berlin
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74370 ARGONAY
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78153 Le Chesnay Cedex
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151 25 MAROUSSI
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35131 PADOVA
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00198 Rome
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16147 GENOVA
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00185 Roma
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1081 HV Amsterdam
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3991CL Houten
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2628 CN DELFT
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1081 HV Amsterdam
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3584 CX Utrecht
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500036 BRASOV
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WC1E 6BT LONDON
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S10 2TN SHEFFIELD
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19355 MALVERN PA
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21218 Baltimore
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20001 Washington Dc
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