Objective
This project aims to provide a comprehensive characterization of the exposure of aquatic organisms to antifungal azoles (AFAs), an emerging pollutant family of particular concern as regard to their endocrine disrupting effects, in the frame of their environmental risk. To this end, this project will address different scientific and technical challenges as regards distribution, bioavailability, toxicokinetic, and (bio)transformation products ((bio)TPs) of AFAs. For this purpose , a multi-disciplinary approach, based on bio-monitoring, passive sampling, effect-driven approach, cutting-edge high resolution mass spectrometry-analyses and laboratory experiments will be implemented. This comprehensive approach will allow (1) to characterize the distribution of AFAs in aquatic systems between sediment, surface water and biota; (2) to identify bioTPs (and biotransformation pathways) of AFAs at different trophic levels but also TPs from other relevant processes (e.g. hydrolysis). This project is original and innovative since it aims to gain knowledge on exposure and identity of (bio)TPs and thus addresses a crucial issue in the assessment of environmental contamination by emerging pollutants and their associated risk. In addition, it proposes to better link exposure and hazard by studying the bioavailability of potentially hazardous chemicals directly in the organisms. It also compare passive sampling vs biomonitoring at different trophic level for a more relevant exposure monitoring of emerging pollutants such as AFAs. This might also enhance human health risk assessment by providing tools for better evaluate exposure, and so risk, associated to consumption of contaminated food (i.e. fish). Finally, if we focus in the present project on AFAs and their (bio)TPs, the approach proposed here could provide a conceptual framework for exposure assessment of other classes of emerging contaminants that would help to enhance actual environmental risk assessment for aquatic organisms.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences ecology ecosystems
- natural sciences earth and related environmental sciences hydrology limnology
- natural sciences biological sciences zoology mammalogy
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
- natural sciences biological sciences zoology invertebrate zoology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2016
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
8600 Dubendorf
Switzerland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.