Mechanical Aspects of Hydra Morphogenesis

Project Information

HydraMechanics

Grant agreement ID: 819174

DOI

10.3030/819174

Project closed

EC signature date 29 January 2019

Start date 1 February 2019

End date 31 January 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (8)

Topological defects in the nematic order of actin fibers as organization centers of Hydra morphogenesis

Author(s): Yonit Maroudas-Sacks; Liora Garion; Lital Shani-Zerbib; Anton Livshits; Erez Braun; Kinneret Keren
Published in: Nature Physics, Issue 17, 2021, Page(s) 251-259, ISSN 1745-2473
Publisher: Nature Publishing Group
DOI: 10.1101/2020.03.02.972539

Plasticity of body axis polarity in<i>Hydra</i>regeneration under constraints

Author(s): Anton Livshits, Liora Garion, Yonit Maroudas-Sacks, Lital Shani-Zerbib, Kinneret Keren, Erez Braun
Published in: Scientific Reports, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1101/2021.02.04.429818

Effective membrane tension: A long-range integrator of cellular dynamics

Author(s): Kinneret Keren
Published in: Cell, Issue 186, 2024, Page(s) 2956-2958, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2023.05.033

Confinement modulates axial patterning in regenerating Hydra

Author(s): Yonit Maroudas-Sacks, Liora Garion, S Suganthan, Marko Popović, Kinneret Keren
Published in: PRX Life, 2024, ISSN 2835-8279
Publisher: American Physical Society
DOI: 10.1101/2024.06.13.598813

Cytoskeletal symmetry breaking in animal cells

Author(s): Niv Ierushalmi, Kinneret Keren
Published in: Current Opinion in Cell Biology, Issue 72, 2023, Page(s) 91-99, ISSN 0955-0674
Publisher: Elsevier BV
DOI: 10.1016/j.ceb.2021.07.003

Mechanical strain focusing at topological defect sites in regenerating <i>Hydra</i>

Author(s): Yonit Maroudas-Sacks, S. Suganthan, Liora Garion, Yael Ascoli-Abbina, Ariel Westfried, Noam Dori, Iris Pasvinter, Marko Popović, Kinneret Keren
Published in: Development, Issue 152, 2025, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.204514

Learning active nematics one step at a time

Author(s): Anna Frishman, Kinneret Keren
Published in: Proceedings of the National Academy of Sciences, Issue 118, 2022, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2102169118

Canalized Morphogenesis Driven by Inherited Tissue Asymmetries in Hydra Regeneration

Author(s): Lital Shani-Zerbib; Liora Garion; Yonit Maroudas-Sacks; Erez Braun; Kinneret Keren
Published in: Genes; Volume 13; Issue 2; Pages: 360, Issue 2, 2022, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes13020360

Non-peer reviewed articles (2)

Mechanical Patterning in Animal Morphogenesis

Author(s): Yonit Maroudas-Sacks, Kinneret Keren
Published in: Annual Review of Cell and Developmental Biology, Issue 37/1, 2021, ISSN 1081-0706
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-cellbio-120319-030931

Roadmap for the multiscale coupling of biochemical and mechanical signals during development

Author(s): Pierre-François Lenne, Edwin Munro, Idse Heemskerk, Aryeh Warmflash, Laura Bocanegra-Moreno, Kasumi Kishi, Anna Kicheva, Yuchen Long, Antoine Fruleux, Arezki Boudaoud, Timothy E Saunders, Paolo Caldarelli, Arthur Michaut, Jerome Gros, Yonit Maroudas-Sacks, Kinneret Keren, Edouard Hannezo, Zev J Gartner, Benjamin Stormo, Amy Gladfelter, Alan Rodrigues, Amy Shyer, Nicolas Minc, Jean-Léon Maître,
Published in: Physical Biology, Issue 18/4, 2021, Page(s) 041501, ISSN 1478-3967
Publisher: Institute of Physics Publishing
DOI: 10.1088/1478-3975/abd0db

Thesis and dissertations (3)

Actin organization and the influence of mechanical constraints on morphogenesis in Hydra regeneration

Author(s): Yonit Maroudas-Sacks
Published in: PhD thesis, 2023
Publisher: Technion

Structural Organization and Body-Axis Polarity in Regeneration of Fused Hydra Tissues

Author(s): Anton Livshits
Published in: PhD Thesis, 2020
Publisher: Technion

The relation between body axis polarity and mechanical processes in morphogenesis during Hydra regeneration

Author(s): Lital Shani-Zerbib
Published in: PhD Thesis, 2022
Publisher: Technion