Objective
"Fish farming is growing at 8% a year and will soon be the main source of fish for consumers. It supplies more than 34% of the world's fish consumption. Nevertheless, due to captivity environment some species have reproduction problems with no spontaneous ovulation in females and no spermiation in males. In some farmed freshwater species (ie, Carp, Salmon, Trout) and marine species (ie, Sea bass, Sea bream) the growth phase of reproductive development occursin captivity in contrast to oocyte maturation and ovulation in females, and spermiation in males that do not occur spontaneously. This problem requires exogenous hormonal therapies which are the only way to produce fertilized eggs reliably. In other species, these hormonal manipulations are used only as a management tool to enhance the efficiency of egg production, increase spermiation and facilitate hatchery operations.
ReproPharm Vet developed a first in class monoclonal antibody RP01 and its fragment RP001, that are able to potentiate the activity of endogenous FSH and LH in mammals such as rat, bovine, ovine, porcine species. RP001 fragment can induce ovulation in female and stimulate spermatogenesis in male without any exogenous hormone injection. When injected, it acts directly on circulating FSH and LH hormones by binding to them and potentiating their activity. RP001 is more effective than conventional hormonal treatments it induces a better ovulation rate in polyovulating species and a better steroidogenic response in every species.
Treatment with potentiating RP001 would be a highly innovative solution, hormone free, which could be a disrupting product in fishing market if we demonstrate its efficacy on fish FSH and LH. Its added value would be a more efficient method to induce ovulation and spermatogenesis without any exogenous hormone injection. RP001 would be a ""must-have"" product to better control fish reproduction in a natural and sustainable way that represents a special issue on environment.
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Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- agricultural sciences agriculture, forestry, and fisheries fisheries
- agricultural sciences agriculture, forestry, and fisheries agriculture
- agricultural sciences animal and dairy science domestic animals animal husbandry
- medical and health sciences clinical medicine endocrinology
- natural sciences biological sciences zoology mammalogy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
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H2020-EU.3. - PRIORITY 'Societal challenges
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H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
37380 NOUZILLY
France
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.