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CORDIS - EU research results
CORDIS

Development, dIagnostic and prevention of gender-related Somatic and mental COmorbitiEs in iRritable bowel syndrome In Europe

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Mechanistically-oriented sex-specific molecular signature of IBS comorbidities following animal and human microbiota transfer (opens in new window)

Mechanistically-oriented sex-specific molecular signature of IBS comorbidities following animal and human microbiota transfer (M40).

Report on IBS pattern comorbidities in retrospective cohorts (opens in new window)

Report on IBS pattern comorbidities in retrospective cohorts (M16).

Report on candidate mechanisms for comorbid development and mechanistic biomarkers from existing data (opens in new window)

Report on candidate mechanisms for comorbid development and mechanistic biomarkers from existing data (M18).

Report on candidate mechanisms and biomarkers for comorbid IBS (opens in new window)

Report on candidate mechanisms and biomarkers for comorbid IBS (M48).

Report on effect of approved drugs on candidate mechanisms (opens in new window)

Report on effect of approved drugs on candidate mechanisms (M48).

To integrate the data provided by ESM app and HumanITcare platform with data from WP2-6 and to feed the repository (opens in new window)

To integrate the data provided by ESM app and HumanITcare platform with data from WP2-6 and to feed the repository (M40).

Intestinal mucosal profiling of mechanisms of barrier dysfunction that differentiate IBS from comorbid IBS (opens in new window)

Intestinal mucosal profiling of mechanisms of barrier dysfunction that differentiate IBS from comorbid IBS (M36).

Report on fecal sampling and transport of IBS cohorts in the project and the quantitative microbiome profiling (opens in new window)

Report on fecal sampling and transport of IBS cohorts in the project and the quantitativemicrobiome profiling (M30).

Report on IBS pattern comorbidities in prospectively deeply phenotyped cohorts (opens in new window)

Report on IBS pattern comorbidities in prospectively deeply phenotyped cohorts (M36).

Confirmation of transfer of comorbid IBS phenotypes from animal models and from human samples (opens in new window)

Confirmation of transfer of comorbid IBS phenotypes from animal models and from humansamples (M40).

Identification of common genetic variants involved in IBS and comorbidities (opens in new window)

Identification of common genetic variants involved in IBS and comorbidities (M36).

"Profiling of ""gut-to-brain"" and ""brain-to-gut"" mechanisms associated with comorbidities development in IBS" (opens in new window)

Profiling of “gut-to-brain” and “brain-to-gut” mechanisms associated with comorbiditiesdevelopment in IBS (M36).

Report on microbiome and metabolome profiling in IBS and comorbid IBS (opens in new window)

Report on microbiome and metabolome profiling in IBS and comorbid IBS (M31).

Publications

Gut microbiota composition links to variation in functional domains across psychiatric disorders (opens in new window)

Author(s): Danique Mulder, Babette Jakobi, Yingjie Shi, Peter Mulders, Josina D. Kist, Rose M. Collard, Janna N. Vrijsen, Phillip van Eijndhoven, Indira Tendolkar, Mirjam Bloemendaal, Alejandro Arias Vasquez
Published in: Brain, Behavior, and Immunity, Issue 120, 2024, Page(s) 275-287, ISSN 0889-1591
Publisher: Academic Press
DOI: 10.1016/j.bbi.2024.05.037

Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new genetic hits (opens in new window)

Author(s): Silvia Alemany; María Soler Artigas; Judit Cabana; Dana Salim Fakhreddine; Natalia Llonga; Laura Vilar-Ribó; Amanda Rodríguez-Urrutia; Judit Palacio; Ana María González-Castro; Beatriz Lobo; Carmen Alonso-Cotoner; Magnus Simrén; Javier Santos; Josep Antoni Ramos-Quiroga; Marta Ribasés
Published in: Journal of Transnational Medicine, Issue 3, 2023, ISSN 1479-5876
Publisher: BioMed Central
DOI: 10.1101/2023.01.30.23285080

The effect of expectancy versus actual gluten intake on gastrointestinal and extra-intestinal symptoms in non-coeliac gluten sensitivity: a randomised, double-blind, placebo-controlled, international, multicentre study (opens in new window)

Author(s): Marlijne C G de Graaf, Clare L Lawton, Fiona Croden, Agnieszka Smolinska, Bjorn Winkens, Martine A M Hesselink, Gonny van Rooy, Peter L Weegels, Peter R Shewry, Peter D Mooney, Lesley A Houghton, Ben J M Witteman, Daniel Keszthelyi, Fred J P H Brouns, Louise Dye, Daisy M A E Jonkers
Published in: The Lancet Gastroenterology & Hepatology, Issue 9, 2025, Page(s) 110-123, ISSN 2468-1253
Publisher: Elsevier BV
DOI: 10.1016/s2468-1253(23)00317-5

Sex specific gut-microbiota signatures of resilient and comorbid gut-brain phenotypes induced by early life stress (opens in new window)

Author(s): Lars Wilmes, Valentina Caputi, Thomaz F.S. Bastiaanssen, James M. Collins, Fiona Crispie, Paul D. Cotter, Timothy G. Dinan, John F. Cryan, Gerard Clarke, Siobhain M. O'Mahony
Published in: Neurobiology of Stress, Issue 33, 2024, Page(s) 100686, ISSN 2352-2895
Publisher: Elsevier BV
DOI: 10.1016/j.ynstr.2024.100686

Refining physical exercise training studies in patients with inflammatory bowel disease: patient selection and assessment of physical fitness changes (opens in new window)

Author(s): Karlijn Demers, Bart C. Bongers, Daisy M. A. E. Jonkers, Marieke J. Pierik, Laurents P. S. Stassen
Published in: Trials, Issue 25, 2024, ISSN 1745-6215
Publisher: BioMed Central
DOI: 10.1186/s13063-024-08163-0

Of bowels, brain and behavior: A role for the gut microbiota in psychiatric comorbidities in irritable bowel syndrome (opens in new window)

Author(s): Lars Wilmes, James M. Collins, Kenneth J. O'Riordan, Siobhain M. O’Mahony, John F. Cryan, Gerard Clarke
Published in: Neurogastroenterology & Motility, Issue 33/3, 2021, ISSN 1350-1925
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/nmo.14095

Investigating causality with fecal microbiota transplantation in rodents: applications, recommendations and pitfalls. (opens in new window)

Author(s): Cassandra E. Gheorghe; Nathaniel L. Ritz; Jason A. Martin; Hannah R. Wardill; John F. Cryan; Gerard Clarke
Published in: Gut Microbes, Vol 13, Iss 1 (2021), Issue 3, 2021, ISSN 1949-0984
Publisher: Gut Microbes (Taylor & Francis Group)
DOI: 10.1080/19490976.2021.1941711

Criterion Validity of Screening Tools and Field-Based Tests for Health-Related Physical Fitness in Inflammatory Bowel Disease (opens in new window)

Author(s): Karlijn Demers, Bart C. Bongers, Sander M. J. van Kuijk, Guy Plasqui, Daisy M. A. E. Jonkers, Marieke J. Pierik, Laurents P. S. Stassen
Published in: Digestive Diseases and Sciences, Issue 69, 2024, Page(s) 4072-4088, ISSN 0163-2116
Publisher: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10620-024-08682-5

A trial‐based economic evaluation of peppermint oil for the treatment of irritable bowel syndrome (opens in new window)

Author(s): Zsa Zsa R. M. Weerts, Brigitte A. B. Essers, Daisy M. A. E. Jonkers, Jeresa I. A. Willems, Deborah J. P. A. Janssen, Ben J. M. Witteman, Cees H. M. Clemens, Audrey Westendorp, Ad A. M. Masclee, Daniel Keszthelyi
Published in: United European Gastroenterology Journal, Issue 9, 2023, Page(s) 997-1006, ISSN 2050-6406
Publisher: Wiley
DOI: 10.1002/ueg2.12134

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