Synthetic Active Droplets Inspired by Life

Informazioni relative al progetto

ActiDrops

ID dell’accordo di sovvenzione: 852187

DOI

10.3030/852187

Progetto chiuso

Data della firma CE 14 Ottobre 2019

Data di avvio 1 Febbraio 2020

Data di completamento 31 Gennaio 2025

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 491 350,00

Contributo UE

€ 1 491 350,00

Coordinato da

TECHNISCHE UNIVERSITAET MUENCHEN
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (26)

Design rules for reciprocal coupling in chemically fueled assembly

Autori: Xiaoyao Chen, Brigitte A. K. Kriebisch, Alexander M. Bergmann, Job Boekhoven
Pubblicato in: Chemical Science, Numero 14, 2024, Pagina/e 10176-10183, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d3sc02062b

Active coacervate droplets as a model for membraneless organelles and protocells

Autori: Carsten Donau, Fabian Späth, Marilyne Sosson, Brigitte A. K. Kriebisch, Fabian Schnitter, Marta Tena-Solsona, Hyun-Seo Kang, Elia Salibi, Michael Sattler, Hannes Mutschler, Job Boekhoven
Pubblicato in: Nature Communications, Numero 11/1, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-18815-9

Chemically fueled materials with a self-immolative mechanism: transient materials with a fast on/off response

Autori: Patrick S. Schwarz, Laura Tebcharani, Julian E. Heger, Peter Müller-Buschbaum, Job Boekhoven
Pubblicato in: Chemical Science, Numero 12/29, 2021, Pagina/e 9969-9976, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d1sc02561a

Fuel-Driven Dynamic Combinatorial Libraries

Autori: Christine M. E. Kriebisch, Alexander M. Bergmann, Job Boekhoven
Pubblicato in: Journal of the American Chemical Society, Numero 143/20, 2021, Pagina/e 7719-7725, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.1c01616

Synthesis and characterization of chemically fueled supramolecular materials driven by carbodiimide-based fuels

Autori: Fabian Schnitter, Alexander M. Bergmann, Benjamin Winkeljann, Jennifer Rodon Fores, Oliver Lieleg, Job Boekhoven
Pubblicato in: Nature Protocols, Numero 16, 2021, Pagina/e 3901-3932, ISSN 1754-2189
Editore: Nature Publishing Group
DOI: 10.1038/s41596-021-00563-9

Liquid spherical shells are a non-equilibrium steady state of active droplets

Autori: Alexander M. Bergmann, Jonathan Bauermann, Giacomo Bartolucci, Carsten Donau, Michele Stasi, Anna-Lena Holtmannspötter, Frank Jülicher, Christoph A. Weber, Job Boekhoven
Pubblicato in: Nature Communications, Numero 14, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-42344-w

Regulating Nucleic Acid Catalysis Using Active Droplets

Autori: Anna‐Lena Holtmannspötter, Corbin Machatzke, Christian Begemann, Elia Salibi, Carsten Donau, Fabian Späth, Job Boekhoven, Hannes Mutschler
Pubblicato in: Angewandte Chemie International Edition, Numero 63, 2024, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202412534

Chemically Driven Division of Protocells by Membrane Budding

Autori: Pablo Zambrano, Xiaoyao Chen, Christine M. E. Kriebisch, Brigitte A. K. Kriebisch, Oleksii Zozulia, Job Boekhoven
Pubblicato in: Journal of the American Chemical Society, Numero 146, 2024, Pagina/e 33359-33367, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.4c08226

Carbodiimide-fueled catalytic reaction cycles to regulate supramolecular processes

Autori: Patrick S. Schwarz; Marta Tena-Solsona; Kun Dai; Job Boekhoven
Pubblicato in: Chemical Communications, Numero 3, 2022, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/d1cc06428b

Acyl Phosphates as Chemically Fueled Building Blocks for Self‐Sustaining Protocells

Autori: Oleksii Zozulia, Christine M. E. Kriebisch, Brigitte A. K. Kriebisch, Héctor Soria‐Carrera, Kingu Rici Ryadi, Juliana Steck, Job Boekhoven
Pubblicato in: Angewandte Chemie, Numero 136, 2025, ISSN 0044-8249
Editore: Wiley
DOI: 10.1002/ange.202406094

The Multifunctional Role of Templates in Chemically Fueled Dynamic Combinatorial Libraries

Autori: Christine M. E. Kriebisch, Brigitte A. K. Kriebisch, Juliette Langlais, Anton S. Maier, Bernhard Rieger, Dieter Braun, Job Boekhoven
Pubblicato in: ChemSystemsChem, 2025, ISSN 2570-4206
Editore: ChemSystemsChem
DOI: 10.1002/syst.202400087

Evolution and Single-Droplet Analysis of Fuel-Driven Compartments by Droplet-Based Microfluidics

Autori: Alexander M. Bergmann, Carsten Donau, Fabian Späth,Kevin Jahnke, Kerstin Göpfrich,Job Boekhoven
Pubblicato in: Angewandte Chemie, Numero 15213773, 2022, ISSN 1521-3773
Editore: Wiley
DOI: 10.1002/anie.202203928

A chemically fueled supramolecular glue for self-healing gels

Autori: Jennifer Rodon-Fores, Michaela A. Würbser, Martin Kretschmer, Benedikt Rieß , Alexander M. Bergmann, Oliver Lieleg, Job Boekhoven
Pubblicato in: Chemical Science, Numero 20416539, 2022, ISSN 2041-6539
Editore: Royal Society
DOI: 10.1039/d2sc03691f

Template-based copying in chemically fuelled dynamic combinatorial libraries

Autori: Christine M. E. Kriebisch, Ludwig Burger, Oleksii Zozulia, Michele Stasi, Alexander Floroni, Dieter Braun, Ulrich Gerland, Job Boekhoven
Pubblicato in: Nature Chemistry, Numero 16, 2024, Pagina/e 1240-1249, ISSN 1755-4330
Editore: Nature Publishing Group
DOI: 10.1038/s41557-024-01570-5

Molecular Design of Chemically Fueled Peptide–Polyelectrolyte Coacervate-Based Assemblies

Autori: Fabian Späth, Carsten Donau, Alexander M. Bergmann, Moritz Kränzlein, Christopher V. Synatschke, Bernhard Rieger, Job Boekhoven
Pubblicato in: Journal of the American Chemical Society, Numero 143/12, 2021, Pagina/e 4782-4789, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.1c01148

Chemically Fueled Block Copolymer Self‐Assembly into Transient Nanoreactors**

Autori: Michaela A. Würbser, Patrick S. Schwarz, Jonas Heckel, Alexander M. Bergmann, Andreas Walther, Job Boekhoven
Pubblicato in: ChemSystemsChem, 2021, ISSN 2570-4206
Editore: Chem Systems Chem
DOI: 10.1002/syst.202100015

Active droplets through enzyme-free, dynamic phosphorylation

Autori: Simone M. Poprawa, Michele Stasi, Brigitte A. K. Kriebisch, Monika Wenisch, Judit Sastre, Job Boekhoven
Pubblicato in: Nature Communications, Numero 15, 2024, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-024-48571-z

Phase Transitions in Chemically Fueled, Multiphase Complex Coacervate Droplets

Autori: Carsten Donau, Fabian Späth, Michele Stasi, Alexander M. Bergmann, Job Boekhoven
Pubblicato in: Angewandte Chemie, Numero 15213773, 2022, ISSN 1521-3773
Editore: Wiley
DOI: 10.1002/anie.202211905

Regulating DNA-Hybridization Using a Chemically Fueled Reaction Cycle

Autori: Michele Stasi, Alba Monferrer, Leon Babl, Sreekar Wunnava, Christina Felicitas Dirscherl, Dieter Braun, Petra Schwille, Hendrik Dietz, Job Boekhoven
Pubblicato in: Journal of the American Chemical Society, Numero 144, 2023, Pagina/e 21939-21947, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.2c08463

Morphological transitions in chemically fueled self-assembly

Autori: Kun Dai; Marta Tena-Solsona; Jennifer Rodon Fores; Alexander M. Bergmann; Job Boekhoven
Pubblicato in: Nanoscale, Numero 4, 2022, ISSN 2040-3372
Editore: Royal Society for Chemistry
DOI: 10.1039/d1nr04954b

Size control and oscillations of active droplets in synthetic cells

Autori: Judit Sastre, Advait Thatte, Alexander M. Bergmann, Michele Stasi, Marta Tena-Solsona, Christoph A. Weber, Job Boekhoven
Pubblicato in: Nature Communications, Numero 16, 2025, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-025-57240-8

A Carbodiimide-Fueled Reaction Cycle That Forms Transient 5(4<i>H</i>)-Oxazolones

Autori: Xiaoyao Chen, Michele Stasi, Jennifer Rodon-Fores, Paula F. Großmann, Alexander M. Bergmann, Kun Dai, Marta Tena-Solsona, Bernhard Rieger, Job Boekhoven
Pubblicato in: Journal of the American Chemical Society, Numero 145, 2023, Pagina/e 6880-6887, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.3c00273

Accelerated Ripening in Chemically Fueled Emulsions**

Autori: Marta Tena‐Solsona, Jacqueline Janssen, Caren Wanzke, Fabian Schnitter, Hansol Park, Benedikt Rieß, Julianne M. Gibbs, Christoph A. Weber, Job Boekhoven
Pubblicato in: ChemSystemsChem, Numero 3/2, 2021, ISSN 2570-4206
Editore: ChemSystemsChem
DOI: 10.1002/syst.202000034

Reciprocal Coupling in Chemically Fueled Assembly: A Reaction Cycle Regulates Self-Assembly and Vice Versa

Autori: Brigitte A. K. Kriebisch, Alexander Jussupow, Alexander M. Bergmann, Fabian Kohler, Hendrik Dietz, Ville R. I. Kaila, Job Boekhoven
Pubblicato in: Journal of the American Chemical Society, Numero 142/49, 2020, Pagina/e 20837-20844, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.0c10486

Parasitic behavior in competing chemically fueled reaction cycles

Autori: Patrick S. Schwarz, Sudarshana Laha, Jacqueline Janssen, Tabea Huss, Job Boekhoven, Christoph A. Weber
Pubblicato in: Chemical Science, Numero 12/21, 2021, Pagina/e 7554-7560, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d1sc01106e

The Role of Chemically Innocent Polyanions in Active, Chemically Fueled Complex Coacervate Droplets

Autori: Fabian Späth, Anton S. Maier, Michele Stasi, Alexander M. Bergmann, Kerstin Halama, Monika Wenisch, Bernhard Rieger, Job Boekhoven
Pubblicato in: Angewandte Chemie International Edition, Numero 62, 2023, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202309318