Advancing Lactobacillus’ beneficial potential

Project Information

Lacto-Be

Grant agreement ID: 852600

DOI

10.3030/852600

Project closed

EC signature date 3 February 2020

Start date 1 March 2020

End date 28 February 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 581,00

EU contribution

€ 1 499 581,00

Coordinated by

UNIVERSITEIT ANTWERPEN
Belgium

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (37)

The Greenhouse Phyllosphere Microbiome and Associations with Introduced Bumblebees and Predatory Mites

Author(s): Marie Legein, Wenke Smets, Karen Wuyts, Lien Bosmans, Roeland Samson, Sarah Lebeer
Published in: Microbiology Spectrum, Issue 10, 2022, ISSN 2165-0497
Publisher: American Society for Microbiology
DOI: 10.1128/spectrum.01755-22

Lactobacillus isalae sp. nov., isolated from the female reproductive tract

Author(s): Tom Eilers, Jelle Dillen, Sarah Ahannach, Leonore Vander Donck, Nele Van de Vliet, Stijn Wittouck, Sarah Lebeer
Published in: International Journal of Systematic and Evolutionary Microbiology, Issue 73, 2023, ISSN 1466-5026
Publisher: Society for General Microbiology
DOI: 10.1099/ijsem.0.006038

Distribution of C30 carotenoid biosynthesis genes suggests habitat adaptation function in insect-adapted and nomadic Lactobacillaceae

Author(s): Tom Eilers, Marie Legein, Jari Temmermans, Jelle Dillen, Ine Vandendriessche, Koen Sandra, Peter A. Bron, Stijn Wittouck, Sarah Lebeer
Published in: Communications Biology, Issue 7, 2024, Page(s) 1610, ISSN 2399-3642
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s42003-024-07291-2

The role of lactobacilli in inhibiting skin pathogens

Author(s): Lize Delanghe, Irina Spacova, Joke Van Malderen, Eline Oerlemans, Ingmar Claes, Sarah Lebeer
Published in: Biochemical Society Transactions, Issue 49/2, 2021, Page(s) 617-627, ISSN 0300-5127
Publisher: Portland Press, Ltd.
DOI: 10.1042/bst20200329

Lactic acid bacteria as probiotics for the nose?

Author(s): Ilke De Boeck, Irina Spacova, Olivier M. Vanderveken, Sarah Lebeer
Published in: Microbial biotechnology, Issue 17517915, 2021, Page(s) 859-869, ISSN 1751-7915
Publisher: Society for Applied Microbiology
DOI: 10.1111/1751-7915.13759

Antimicrobial potential of known and novel probiotics on in vitro periodontitis biofilms

Author(s): Wannes Van Holm, Rita Carvalho, Lize Delanghe, Tom Eilers, Naiera Zayed, Fabian Mermans, Kristel Bernaerts, Nico Boon, Ingmar Claes, Sarah Lebeer & Wim Teughels
Published in: npj Biofilms and Microbiomes, Issue 9 :1 (2023) ,, 2023, Page(s) p. 1-12, ISSN 2055-5008
Publisher: Nature Publishing Group
DOI: 10.1038/s41522-023-00370-y

The nasal mutualist Dolosigranulum pigrum AMBR11 supports homeostasis via multiple mechanisms

Author(s): Ilke De Boeck, Stijn Wittouck, Katleen Martens, Irina Spacova, Eline Cauwenberghs, Camille Nina Allonsius, Jennifer Jörissen, Sander Wuyts, Wannes Van Beeck, Jelle Dillen, Peter A Bron, Brecht Steelant, Peter W Hellings, Olivier M Vanderveken, Sarah Lebeer
Published in: iScience, Issue 25890042, 2021, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2021.102978

The biocontrol agent <i>Lactiplantibacillus plantarum</i> AMBP214 is dispersible to plants via bumblebees

Author(s): Jari Temmermans, Marie Legein, Yijie Zhao, Filip Kiekens, Guy Smagghe, Barbara de Coninck, Sarah Lebeer
Published in: Applied and Environmental Microbiology, Issue 89, 2023, ISSN 0099-2240
Publisher: American Society for Microbiology
DOI: 10.1128/aem.00950-23

Relationship between classic indicators of health behaviour and contraceptive choices in women in Flanders

Author(s): Nina Van Eekert, Naomi Biegel, Leen De Kort, Veronique Verhoeven, Thies Gehrmann, Caroline Masquillier, Sarah Ahannach, Sarah Lebeer
Published in: BMC Women's Health, Issue 24, 2024, Page(s) 275, ISSN 1472-6874
Publisher: BioMed Central
DOI: 10.1186/s12905-024-03079-y

Impacts of Menstruation, Community Type, and an Oral Yeast Probiotic on the Vaginal Microbiome

Author(s): Eline Oerlemans, Sarah Ahannach, Stijn Wittouck, Elodie Dehay, Ilke De Boeck, Natalhie Ballet, Bertrand Rodriguez, Ines Tuyaerts, Sarah Lebeer
Published in: mSphere, Issue 7: 5 (2022), 2022, Page(s) p. 1-13, ISSN 2379-5042
Publisher: Amer soc microbiology
DOI: 10.1128/msphere.00239-22

Microbial enrichment and storage for metagenomics of vaginal, skin, and saliva samples

Author(s): Sarah Ahannach, Lize Delanghe Irina Spacova, Stijn Wittouck, Wannes Van Beeck, Ilke De Boeck, Sarah Lebeer
Published in: iScience, Issue 25890042, 2021, Page(s) 1-20, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2021.103306

Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

Author(s): Katherine M. Kennedy, Marcus C. de Goffau, Maria Elisa Perez-Muñoz, Marie-Claire Arrieta, Fredrik Bäckhed, Peer Bork, Thorsten Braun, Frederic D. Bushman, Joel Dore, Willem M. de Vos, Ashlee M. Earl, Jonathan A. Eisen, Michal A. Elovitz, Stephanie C. Ganal-Vonarburg, Michael G. Gänzle, Wendy S. Garrett, Lindsay J. Hall, Mathias W. Hornef, Curtis Huttenhower, Liza Konnikova, Sarah Lebeer, Andrew
Published in: Nature, Issue 613, 2023, Page(s) 639–649, ISSN 1476-4687
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-022-05546-8

Latilactobacillus fragifolii sp. nov., isolated from leaves of a strawberry plant (Fragaria x ananassa)

Author(s): Marie Legein, Stijn Wittouck, Sarah Lebeer
Published in: International journal of systematic and evolutionary microbiology, Issue 14665026, 2022, Page(s) 1-9, ISSN 1466-5026
Publisher: Society for General Microbiology
DOI: 10.1099/ijsem.0.005193

Topical Microbial Therapeutics against Respiratory Viral Infections

Author(s): Irina Spacova, Ilke De Boeck, Peter A Bron, Peter Delputte, Sarah Lebeer
Published in: Trends in molecular medicine, Issue 14714914, 2021, Page(s) 538-553, ISSN 1471-4914
Publisher: Elsevier BV
DOI: 10.1016/j.molmed.2021.03.009

Tidytacos: An R package for analyses on taxonomic composition of microbial communities

Author(s): Stijn Wittouck, Tim Van Rillaer, Wenke Smets, Sarah Lebeer
Published in: Journal of Open Source Software, Issue 10, 2025, Page(s) 6313, ISSN 2475-9066
Publisher: The Open Journal
DOI: 10.21105/joss.06313

At the Interface of Life and Death: Post-mortem and Other Applications of Vaginal, Skin, and Salivary Microbiome Analysis in Forensics

Author(s): Sarah Ahannach, Irina Spacova, Ronny Decorte, Els Jehaes and Sarah Lebeer.
Published in: Frontiers in Microbiology, Issue 1664302X, 2021, Page(s) 1-10, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2021.694447

Randomized, Double-Blind, Placebo-Controlled Trial of a Throat Spray with Selected Lactobacilli in COVID-19 Outpatients

Author(s): Ilke De Boeck, Eline Cauwenberghs, Irina Spacova, Thies Gehrmann, Tom Eilers, Lize Delanghe, Stijn Wittouck , Peter A. Bron, Tim Henkens, Imane Gamgami, Alix Simons, Ingmar Claes, Joachim Mariën, Kevin K. Ariën, Diana Bakokimi, Katherine Loens, Kevin Jacobs, Margareta Ieven, Patricia Bruijning-Verhagen, Peter Delputte, Samuel Coenen, Veronique Verhoeven, Sarah Lebeer
Published in: Microbiology Spectrum, Issue 10 :5 (2022), 2022, Page(s) p. 1-14, ISSN 2165-0497
Publisher: ASM Press
DOI: 10.1128/spectrum.01682-22

Selective targeting of skin pathobionts and inflammation with topically applied lactobacilli

Author(s): Sarah Lebeer, Eline Oerlemans, Ingmar Claes, Tim Henkens, Lize Delanghe, Sander Wuyts, Irina Spacova, Marianne F.L. van den Broek, Ines Tuyaerts, Stijn Wittouck, Ilke De Boeck, Camille Allonsius, Filip Kiekens, Julien Lambert
Published in: Cell Reports Medicine, Issue 26663791, 2022, Page(s) 1-14, ISSN 2666-3791
Publisher: Cell Press
DOI: 10.1016/j.xcrm.2022.100521

Recent Insights into the vaginal microbiota

Author(s): Sandra Condori, Sarah Ahannach, Leonore Vander Donck, Eline Oerlemans, Jelle Dillen, Caroline Dricot, Thies Gehrmann, Irina Spacova, Sarah Lebeer
Published in: Microbiome in health and disease, Issue 27048845, 2022, Page(s) 1-12, ISSN 2704-8845
Publisher: European Helicobacter & Microbiota Study Group
DOI: 10.26355/mhd_20229_771

Mild atopic dermatitis is characterized by increase in non-staphylococcus pathobionts and loss of specific species

Author(s): Lize Delanghe, Ilke De Boeck, Joke Van Malderen, Camille Nina Allonsius, Tim Van Rillaer, Peter A. Bron, Ingmar Claes, Margo Hagendorens, Sarah Lebeer, Julie Leysen
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-74513-2

Spontaneous Riboflavin-Overproducing Limosilactobacillus reuteri for Biofortification of Fermented Foods

Author(s): Irina Spacova, Sarah Ahannach, Annelies Breynaert, Isabel Erreygers, Stijn Wittouck, Peter A. Bron, Wannes Van Beeck, Tom Eilers, Abbas Alloul, Naïm Blansaer, Siegfried E. Vlaeminck, Nina Hermans, Sarah Lebeer
Published in: Frontiers in Nutrition, Issue 9:916607, 2022, ISSN 2296-861X
Publisher: Frontiers Media S.A
DOI: 10.3389/fnut.2022.916607

Cotton and Surgical Face Masks in Community Settings: Bacterial Contamination and Face Mask Hygiene

Author(s): Lize Delanghe, Eline Cauwenberghs, Irina Spacova, Ilke De Boeck, Wannes Van Beeck, Koen Pepermans, Ingmar Claes, Dieter Vandenheuvel, Veronique Verhoeven, Sarah Lebeer
Published in: Frontiers in medicine, Issue 2296858X, 2021, Page(s) 1-12, ISSN 2296-858X
Publisher: Frontiers Media S.A.
DOI: 10.3389/fmed.2021.732047

Postbiotics in the medical field under the perspective of the ISAPP definition: scientific, regulatory, and marketing considerations

Author(s): Gabriel Vinderola, Céline Druart, Luis Gosálbez, Seppo Salminen, Nina Vinot, Sarah Lebeer
Published in: Frontiers in Pharmacology, Issue 14, 2023, ISSN 1663-9812
Publisher: Frontiers Media S.A.
DOI: 10.3389/fphar.2023.1239745

A taxonomic note on the genus Lactobacillus: Description of 23 novel genera, emended description of the genus Lactobacillus Beijerinck 1901, and union of Lactobacillaceae and Leuconostocaceae

Author(s): Jinshui Zheng, Stijn Wittouck, Elisa Salvetti, Charles M.A.P. Franz​, Hugh M.B. Harris, Paola Mattarelli, Paul W. O’Toole, Bruno Pot​, Peter Vandamme, Jens Walter​, Koichi Watanabe​, Sander Wuyts, Giovanna E. Felis, Michael G. Gänzle, Sarah Lebeer
Published in: International Journal of Systematic and Evolutionary Microbiology., Issue 14665026, 2020, Page(s) 2782-2858, ISSN 1466-5026
Publisher: Society for General Microbiology
DOI: 10.1099/ijsem.0.004107

The inner elbow skin microbiome contains <i>Lactobacillus</i> among its core taxa and varies with age, season and lifestyle

Author(s): Lize Delanghe, Ilke De Boeck, Joke Van Malderen, Thies Gehrmann, Camille Nina Allonsius, Peter A. Bron, Ingmar Claes, Margo Hagendorens, Julie Leysen, Stijn Wittouck, Sarah Lebeer
Published in: Microbiome Research Reports, Issue 3, 2024, Page(s) 43, ISSN 2771-5965
Publisher: OAE Publishing Inc
DOI: 10.20517/mrr.2024.23

A citizen-science-enabled catalogue of the vaginal microbiome and associated factors

Author(s): Sarah Lebeer, Sarah Ahannach, Thies Gehrmann, Stijn Wittouck, Tom Eilers, Eline Oerlemans, Sandra Condori, Jelle Dillen, Irina Spacova, Leonore Vander Donck, Caroline Masquillier, Camille Nina Allonsius, Peter A. Bron, Wannes Van Beeck, Charlotte De Backer, Gilbert Donders, Veronique Verhoeven
Published in: Nature Microbiology, Issue 8, 2023, Page(s) 2183-2195, ISSN 2058-5276
Publisher: Nature publishing group
DOI: 10.1038/s41564-023-01500-0

Bacterial Succession and Community Dynamics of the Emerging Leaf Phyllosphere in Spring

Author(s): Wenke Smets, Lucia Maria Spada, Isabella Gandolfi, Karen Wuyts, Marie Legein, Babette Muyshondt, Roeland Samson, Andrea Franzetti, Sarah Lebeer
Published in: Microbiology Spectrum, Issue 10, 2024, Page(s) Volume 10 • Number 2, ISSN 2165-0497
Publisher: ASM Journals
DOI: 10.1128/spectrum.02420-21

Modes of Action of Microbial Biocontrol in the Phyllosphere

Author(s): Marie Legein, Wenke Smets, Dieter Vandenheuvel, Tom Eilers, Babette Muyshondt, Els Prinsen, Roeland Samson and Sarah Lebeer
Published in: Frontiers in Microbiology, Issue 1664302X, 2020, Page(s) 1619, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2020.01619

Positioning the preventive potential of microbiome treatments for cystic fibrosis in the context of current therapies

Author(s): Eline Cauwenberghs, Ilke De Boeck, Irina Spacova, Ilke Van Tente, Joke Bastiaenssen, Elise Lammertyn, Stijn Verhulst, Kim Van Hoorenbeeck, Sarah Lebeer
Published in: Cell Reports Medicine, Issue 5, 2024, Page(s) 101371, ISSN 2666-3791
Publisher: Cell Press
DOI: 10.1016/j.xcrm.2023.101371

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration

Author(s): Mitja M Zdouc, Kai Blin, Nico L L Louwen, Jorge Navarro, Catarina Loureiro, Chantal D Bader, Constance B Bailey, Lena Barra, Thomas J Booth, Kenan A J Bozhüyük, José D D Cediel-Becerra, Zachary Charlop-Powers, Marc G Chevrette, Yit Heng Chooi, Paul M D’Agostino, Tristan de Rond, Elena Del Pup, Katherine R Duncan, Wenjia Gu, Novriyandi Hanif, Eric J N Helfrich, Matthew Jenner, Yoh
Published in: Nucleic Acids Research, Issue 53, 2025, Page(s) D678-D690, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkae1115

Citizen science as an instrument for women’s health research

Author(s): Sarah Ahannach, Ine Van Hoyweghen, Veronique Verhoeven, Sarah Lebeer
Published in: Nature Medicine, Issue 30, 2024, Page(s) 3445-3454, ISSN 1078-8956
Publisher: Nature Publishing Group
DOI: 10.1038/s41591-024-03371-2

Antibacterial and Immunostimulatory Activity of Potential Probiotic Lactic Acid Bacteria Isolated from Ethiopian Fermented Dairy Products

Author(s): Seyoum Gizachew, Wannes Van Beeck, Irina Spacova, Max Dekeukeleire, Ashenafi Alemu, Wude Mihret Woldemedhin, Solomon H. Mariam, Sarah Lebeer, Ephrem Engidawork
Published in: Fermentation, Issue 9, 2023, Page(s) 258, ISSN 2311-5637
Publisher: MDPI
DOI: 10.3390/fermentation9030258

Editorial 14th international symposium on lactic acid bacteria (LAB14)

Author(s): Eddy J Smid, Sarah Lebeer, Egon B Hansen
Published in: FEMS Microbiology Reviews, Issue 47, 2023, ISSN 1574-6976
Publisher: Oxford University Publishing
DOI: 10.1093/femsre/fuad043

Lactiplantibacillus carotarum AMBF275T sp. nov. isolated from carrot juice fermentation

Author(s): Tom Eilers, Jelle Dillen, Nele Van de Vliet, Stijn Wittouck, Sarah Lebeer
Published in: International Journal of Systematic and Evolutionary Microbiology, Issue 73, 2023, ISSN 1466-5026
Publisher: Society for General Microbiology
DOI: 10.1099/ijsem.0.005976

SCARAP: scalable cross-species comparative genomics of prokaryotes

Author(s): Stijn Wittouck, Tom Eilers, Vera van Noort, Sarah Lebeer
Published in: Bioinformatics, Issue 41, 2024, ISSN 1367-4811
Publisher: Oxford University Press (OUP)
DOI: 10.1093/bioinformatics/btae735

After the storm—Perspectives on the taxonomy of Lactobacillaceae

Author(s): Nanzhen Qiao, Stijn Wittouck, Paola Matterelli, Jinshui Zheng, Sarah Lebeer, Giovanna E. Felis, Michael G. Gänzle
Published in: JDS Communications, Issue 26669102, 2022, Page(s) 222-227, ISSN 2666-9102
Publisher: JDS Communications
DOI: 10.3168/jdsc.2021-0183

Diversity in women and their vaginal microbiota

Author(s): Sandra Condori-Catachura, Sarah Ahannach, Monica Ticlla, Josiane Kenfack, Esemu Livo, Kingsley C. Anukam, Viviana Pinedo-Cancino, Maria Carmen Collado, Maria Gloria Dominguez-Bello, Corrie Miller, Gabriel Vinderola, Sonja Merten, Gilbert G.G. Donders, Thies Gehrmann, Sarah Lebeer
Published in: Trends in Microbiology, 2025, ISSN 0966-842X
Publisher: Elsevier BV
DOI: 10.1016/j.tim.2024.12.012

Intellectual Property Rights

Trademark (2)

Isala trademark registration of device mark

Application/Publication number: 14 56355
Date: 2021-12-22
Applicant(s): UNIVERSITEIT ANTWERPEN

Isala trademark registration of device mark

Application/Publication number: 14 56355
Date: 2021-12-22
Applicant(s): UNIVERSITEIT ANTWERPEN