Pioneering Strategies Against Bacterial Infections

Project Information

PEST-BIN

Grant agreement ID: 955626

DOI

10.3030/955626

Project closed

EC signature date 28 August 2020

Start date 1 January 2021

End date 31 December 2024

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 4 144 986,00

EU contribution

€ 4 144 986,00

Coordinated by

DANMARKS TEKNISKE UNIVERSITET
Denmark

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (21)

Diagnostic biomarkers obtained by MS proteomics
MS proteomics analytical pipeline for analysing bacterial infection systems
Graphene-polymer composites with enhanced antibacterial properties, suitable for mass production
Outreach activities accomplished by each ESR
Consolidated list of targets for drug development based on computational analysis
Vacancies advertised
Consolidated list of diagnostic markers based on omics data integration
Functionalized graphene diagnostic chip
Summer School 3 (M33)

Summer School 3

Summer School 2 (M21)

Summer Schools 2 M21

MS proteomics-based targets for drug development
Exploitation of results
Magnetic nanoparticles axially coated with graphene, functionalized with antibiotics
Conferences (M12)

Conferences M12

ESR scientific publications
PhD degrees delivered

PhD degrees delivered. CUT and UGOT ESRs will continue for another year before obtaining their doctoral degrees (local doctoral school rules). PhD degrees in Sweden lasts for minimum 4 years. The last year will be co-financed by CUT and UGOT.

Recruitment workshop
Conferences (M36)
PTM conferences attended by ESRs
Website & associated platforms operational

Website associated platforms operational

New antibiotics discovered by library screening

Publications

Peer reviewed articles (23)

Recent Developments in the Ruthenium‐Catalyzed Azide Alkyne Cycloaddition (RuAAC) Reaction

Author(s): Flavia Ferrara, Tamás Beke‐Somfai, Nina Kann
Published in: European Journal of Organic Chemistry, Issue 27, 2024, ISSN 1434-193X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.202400113

Recent progress in quantitative phosphoproteomics

Author(s): Katharina Zittlau, Payal Nashier, Claudia Cavarischia-Rega, Boris Macek, Philipp Spät, Nicolas Nalpas
Published in: Expert Review of Proteomics, Issue 20, 2024, Page(s) 469-482, ISSN 1478-9450
Publisher: Future Drugs Ltd.
DOI: 10.1080/14789450.2023.2295872

High Mobility Graphene on EVA/PET

Author(s): Munis Khan, Kornelia Indykiewicz, Pui Lam Tam and August Yurgens
Published in: Nanomaterials, Issue 20794991, 2021, ISSN 2079-4991
Publisher: MDPI
DOI: 10.3390/nano12030331

Phosphoproteome Dynamics of Streptomyces rimosus during Submerged Growth and Antibiotic Production

Author(s): Ela Šarić, Gerry A. Quinn, Nicolas Nalpas, Tina Paradžik, Saša Kazazić, Želimira Filić, Maja Šemanjski, Paul Herron, Iain Hunter, Boris Maček, Dušica Vujaklija
Published in: mSystems, Issue 7, 2023, ISSN 2379-5077
Publisher: mSystems
DOI: 10.1128/msystems.00199-22

Orientation of graphene nanosheets in magnetic fields

Author(s): Viney Ghai, Sajjad Pashazadeh, Hengzhi Ruan, Roland Kádár
Published in: Progress in Materials Science, Issue 143, 2024, Page(s) 101251, ISSN 0079-6425
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.pmatsci.2024.101251

Polysaccharide-based antibacterial coating technologies

Author(s): Hengzhi Ruan, Alexandra Aulova, Viney Ghai, Santosh Pandit, Martin Lovmar, Ivan Mijakovic, Roland Kádár
Published in: Acta Biomaterialia, Issue 168, 2024, Page(s) 42-77, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2023.07.023

BacSPaD: A Robust Bacterial Strains’ Pathogenicity Resource Based on Integrated and Curated Genomic Metadata

Author(s): Sara Ribeiro, Guillaume Chaumet, Karine Alves, Julien Nourikyan, Lei Shi, Jean-Pierre Lavergne, Ivan Mijakovic, Simon de Bernard, Laurent Buffat
Published in: Pathogens, Issue 13, 2024, Page(s) 672, ISSN 2076-0817
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pathogens13080672

Graphene Oxide Attenuates Toxicity of Amyloid‐β Aggregates in Yeast by Promoting Disassembly and Boosting Cellular Stress Response

Author(s): Xin Chen, Santosh Pandit, Lei Shi, Vaishnavi Ravikumar, Julie Bonne Køhler, Ema Svetlicic, Zhejian Cao, Abhroop Garg, Dina Petranovic, Ivan Mijakovic
Published in: Advanced Functional Materials, Issue 33, 2024, ISSN 1616-301X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202304053

Proteome Dynamics during Antibiotic Persistence and Resuscitation

Author(s): Maja Semanjski, Fabio Lino Gratani, Till Englert, Payal Nashier, Viktor Beke, Nicolas Nalpas, Elsa Germain, Shilpa George, Christiane Wolz, Kenn Gerdes, Boris Macek
Published in: American Societu for Microbiology, Issue 23795077, 2021, ISSN 2379-5077
Publisher: Amer Soc Microbiology
DOI: 10.1128/msystems.00549-21

The Molecules Gateway: A Homogeneous, Searchable Database of 150k Annotated Molecules from Actinomycetes

Author(s): Matteo Simone, Marianna Iorio, Paolo Monciardini, Massimo Santini, Niccolò Cantù, Arianna Tocchetti, Stefania Serina, Cristina Brunati, Thomas Vernay, Andrea Gentile, Mattia Aracne, Marco Cozzi, Justin J. J. van der Hooft, Margherita Sosio, Stefano Donadio, Sonia I. Maffioli
Published in: Journal of Natural Products, Issue 87, 2024, Page(s) 2615-2628, ISSN 0163-3864
Publisher: American Chemical Society
DOI: 10.1021/acs.jnatprod.4c00857

Molecular dissection of the chromosome partitioning protein RocS and regulation by phosphorylation

Author(s): Margaux Demuysere, Adrien Ducret, Christophe Grangeasse
Published in: Journal of Bacteriology, Issue 206, 2024, ISSN 0021-9193
Publisher: American Society for Microbiology
DOI: 10.1128/jb.00291-24

Bad to the bone? – Genomic analysis of Enterococcus isolates from diverse environments reveals that most are safe and display potential as food fermentation microorganisms

Author(s): Belay Tilahun Tadesse, Ema Svetlicic, Shuangqing Zhao, Nega Berhane, Carsten Jers, Christian Solem, Ivan Mijakovic
Published in: Microbiological Research, Issue 283, 2024, Page(s) 127702, ISSN 0944-5013
Publisher: Elsevier BV
DOI: 10.1016/j.micres.2024.127702

Pleomorphic Variants of Borreliella (syn. Borrelia) burgdorferi Express Evolutionary Distinct Transcriptomes

Author(s): Nina Čorak, Sirli Anniko, Christina Daschkin-Steinborn, Viktoria Krey, Sara Koska, Momir Futo, Tin Široki, Innokenty Woichansky, Luka Opašić, Domagoj Kifer, Anja Tušar, Horst-Günter Maxeiner, Mirjana Domazet-Lošo, Carsten Nicolaus, Tomislav Domazet-Lošo
Published in: International Journal of Molecular Sciences, Issue 24, 2025, Page(s) 5594, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24065594

High mobility graphene field effect transistors on flexible EVA/PET foils

Author(s): Munis Khan, Jie Ji, Binbin Zhou, Peter U Jepsen, Peter Boggild, August Yurgens
Published in: 2D Materials, Issue 11, 2024, Page(s) 035022, ISSN 2053-1583
Publisher: 2D Materials
DOI: 10.1088/2053-1583/ad4b36

A novel time-lapse imaging method for studying developing bacterial biofilms

Author(s): Momir Futo; Tin Široki; Sara Koska; Nina Čorak; Anja Tušar; Mirjana Domazet-Lošo; Tomislav Domazet-Lošo
Published in: Crossref, Issue 1, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-24431-y

Advanced Nanomaterials for Cancer Therapy: Gold, Silver, and Iron Oxide Nanoparticles in Oncological Applications

Author(s): Priyanka Singh, Santosh Pandit, Sri Renukadevi Balusamy, Mukil Madhusudanan, Hina Singh, H. Mohamed Amsath Haseef, Ivan Mijakovic
Published in: Advanced Healthcare Materials, 2024, ISSN 2192-2640
Publisher: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202403059

Graphene thermocouple fabricated on a flexible and transparent substrate

Author(s): Youngwoo Nam, Daewon Gu, Munis Khan, August Yurgens
Published in: AIP Advances, Issue 14, 2024, ISSN 2158-3226
Publisher: American Institute of Physics Inc.
DOI: 10.1063/5.0203178

Genomic characterization and assessment of pathogenic potential of Legionella spp. isolates from environmental monitoring

Author(s): Ema Svetlicic, Daniel Jaén-Luchoro, Roberta Sauerborn Klobucar, Carsten Jers, Snjezana Kazazic, Damjan Franjevic, Goran Klobucar, Brian G. Shelton and Ivan Mijakovic*
Published in: Frontiers in Microbiology, 2023, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2022.1091964

Biomimetic Antibacterial Gelatin Hydrogels with Multifunctional Properties for Biomedical Applications

Author(s): Hengzhi Ruan, Marko Bek, Santosh Pandit, Alexandra Aulova, Jian Zhang, Philip Bjellheim, Martin Lovmar, Ivan Mijakovic, Roland Kádár
Published in: ACS Applied Materials & Interfaces, Issue 15, 2023, Page(s) 54249-54265, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.3c10477

CHAMP delivers accurate taxonomic profiles of the prokaryotes, eukaryotes, and bacteriophages in the human microbiome

Author(s): Sara Pita, Pernille Neve Myers, Joachim Johansen, Jakob Russel, Mads Cort Nielsen, Aron C. Eklund, Henrik Bjørn Nielsen
Published in: Frontiers in Microbiology, Issue 15, 2024, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2024.1425489

An integrated workflow for enhanced taxonomic and functional coverage of the mouse fecal metaproteome

Author(s): Nicolas Nalpas, Lesley Hoyles, Viktoria Anselm, Tariq Ganief, Laura Martinez-GiliORCID Icon, Cristina Grau, Irina Droste-Borel, Laetitia Davidovic, Xavier Altafaj, Marc-Emmanuel Dumas & Boris Macek
Published in: Gut Microbes, Issue 19490976, 2021, ISSN 1949-0976
Publisher: Landes Bioscience
DOI: 10.1080/19490976.2021.1994836

Achieving Long‐Range Arbitrary Uniform Alignment of Nanostructures in Magnetic Fields

Author(s): Viney Ghai, Santosh Pandit, Magnus Svensso, Ragnar Larsson, Aleksandar Matic, Roselle Ngaloy, Saroj P. Dash, Ann Terry, Kim Nygård, Ivan Mijakovic, Roland Kádár
Published in: Advanced Functional Materials, 2024, ISSN 1616-301X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202406875

3D printed inserts for reproducible high throughput screening of cell migration

Author(s): Abhayraj S. Joshi, Mukil Madhusudanan, Ivan Mijakovic
Published in: Frontiers in Cell and Developmental Biology, Issue 11, 2023, ISSN 2296-634X
Publisher: Frontiers
DOI: 10.3389/fcell.2023.1256250

Other (2)

E. coli Toxin YjjJ (HipH) Is a Ser/Thr Protein Kinase That Impacts Cell Division, Carbon Metabolism, and Ribosome Assembly

Author(s): Fabio Lino Gratani, Till Englert, Payal Nashier, Peter Sass, Laura Czech, Niels Neumann, Sofia Doello, Petra Mann, Rudolf Blobelt, Siegfried Alberti, Karl Forchhammer, Gert Bange , Katharina Höfer, Boris Macek
Published in: 2022
Publisher: ASM Journals
DOI: 10.1128/msystems.01043-22

Identifying Novel Determinants of Bacterial Pathogenicity using Phylogenetic-based Orthology Analysis

Author(s): RIBEIRO, Sara
Published in: Issue 1, 2024
Publisher: Zenodo
DOI: 10.5281/zenodo.13694408