Pioneering Strategies Against Bacterial Infections

Informazioni relative al progetto

PEST-BIN

ID dell’accordo di sovvenzione: 955626

DOI

10.3030/955626

Progetto chiuso

Data della firma CE 28 Agosto 2020

Data di avvio 1 Gennaio 2021

Data di completamento 31 Dicembre 2024

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 4 144 986,00

Contributo UE

€ 4 144 986,00

Coordinato da

DANMARKS TEKNISKE UNIVERSITET
Denmark

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (21)

Diagnostic biomarkers obtained by MS proteomics
MS proteomics analytical pipeline for analysing bacterial infection systems
Graphene-polymer composites with enhanced antibacterial properties, suitable for mass production
Outreach activities accomplished by each ESR
Consolidated list of targets for drug development based on computational analysis
Vacancies advertised
Consolidated list of diagnostic markers based on omics data integration
Functionalized graphene diagnostic chip
Summer School 3 (M33)

Summer School 3

Summer School 2 (M21)

Summer Schools 2 M21

MS proteomics-based targets for drug development
Exploitation of results
Magnetic nanoparticles axially coated with graphene, functionalized with antibiotics
Conferences (M12)

Conferences M12

ESR scientific publications
PhD degrees delivered

PhD degrees delivered. CUT and UGOT ESRs will continue for another year before obtaining their doctoral degrees (local doctoral school rules). PhD degrees in Sweden lasts for minimum 4 years. The last year will be co-financed by CUT and UGOT.

Recruitment workshop
Conferences (M36)
PTM conferences attended by ESRs
Website & associated platforms operational

Website associated platforms operational

New antibiotics discovered by library screening

Pubblicazioni

Peer reviewed articles (23)

Recent Developments in the Ruthenium‐Catalyzed Azide Alkyne Cycloaddition (RuAAC) Reaction

Autori: Flavia Ferrara, Tamás Beke‐Somfai, Nina Kann
Pubblicato in: European Journal of Organic Chemistry, Numero 27, 2024, ISSN 1434-193X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.202400113

Recent progress in quantitative phosphoproteomics

Autori: Katharina Zittlau, Payal Nashier, Claudia Cavarischia-Rega, Boris Macek, Philipp Spät, Nicolas Nalpas
Pubblicato in: Expert Review of Proteomics, Numero 20, 2024, Pagina/e 469-482, ISSN 1478-9450
Editore: Future Drugs Ltd.
DOI: 10.1080/14789450.2023.2295872

High Mobility Graphene on EVA/PET

Autori: Munis Khan, Kornelia Indykiewicz, Pui Lam Tam and August Yurgens
Pubblicato in: Nanomaterials, Numero 20794991, 2021, ISSN 2079-4991
Editore: MDPI
DOI: 10.3390/nano12030331

Phosphoproteome Dynamics of Streptomyces rimosus during Submerged Growth and Antibiotic Production

Autori: Ela Šarić, Gerry A. Quinn, Nicolas Nalpas, Tina Paradžik, Saša Kazazić, Želimira Filić, Maja Šemanjski, Paul Herron, Iain Hunter, Boris Maček, Dušica Vujaklija
Pubblicato in: mSystems, Numero 7, 2023, ISSN 2379-5077
Editore: mSystems
DOI: 10.1128/msystems.00199-22

Orientation of graphene nanosheets in magnetic fields

Autori: Viney Ghai, Sajjad Pashazadeh, Hengzhi Ruan, Roland Kádár
Pubblicato in: Progress in Materials Science, Numero 143, 2024, Pagina/e 101251, ISSN 0079-6425
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.pmatsci.2024.101251

Polysaccharide-based antibacterial coating technologies

Autori: Hengzhi Ruan, Alexandra Aulova, Viney Ghai, Santosh Pandit, Martin Lovmar, Ivan Mijakovic, Roland Kádár
Pubblicato in: Acta Biomaterialia, Numero 168, 2024, Pagina/e 42-77, ISSN 1742-7061
Editore: Elsevier BV
DOI: 10.1016/j.actbio.2023.07.023

BacSPaD: A Robust Bacterial Strains’ Pathogenicity Resource Based on Integrated and Curated Genomic Metadata

Autori: Sara Ribeiro, Guillaume Chaumet, Karine Alves, Julien Nourikyan, Lei Shi, Jean-Pierre Lavergne, Ivan Mijakovic, Simon de Bernard, Laurent Buffat
Pubblicato in: Pathogens, Numero 13, 2024, Pagina/e 672, ISSN 2076-0817
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pathogens13080672

Graphene Oxide Attenuates Toxicity of Amyloid‐β Aggregates in Yeast by Promoting Disassembly and Boosting Cellular Stress Response

Autori: Xin Chen, Santosh Pandit, Lei Shi, Vaishnavi Ravikumar, Julie Bonne Køhler, Ema Svetlicic, Zhejian Cao, Abhroop Garg, Dina Petranovic, Ivan Mijakovic
Pubblicato in: Advanced Functional Materials, Numero 33, 2024, ISSN 1616-301X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202304053

Proteome Dynamics during Antibiotic Persistence and Resuscitation

Autori: Maja Semanjski, Fabio Lino Gratani, Till Englert, Payal Nashier, Viktor Beke, Nicolas Nalpas, Elsa Germain, Shilpa George, Christiane Wolz, Kenn Gerdes, Boris Macek
Pubblicato in: American Societu for Microbiology, Numero 23795077, 2021, ISSN 2379-5077
Editore: Amer Soc Microbiology
DOI: 10.1128/msystems.00549-21

The Molecules Gateway: A Homogeneous, Searchable Database of 150k Annotated Molecules from Actinomycetes

Autori: Matteo Simone, Marianna Iorio, Paolo Monciardini, Massimo Santini, Niccolò Cantù, Arianna Tocchetti, Stefania Serina, Cristina Brunati, Thomas Vernay, Andrea Gentile, Mattia Aracne, Marco Cozzi, Justin J. J. van der Hooft, Margherita Sosio, Stefano Donadio, Sonia I. Maffioli
Pubblicato in: Journal of Natural Products, Numero 87, 2024, Pagina/e 2615-2628, ISSN 0163-3864
Editore: American Chemical Society
DOI: 10.1021/acs.jnatprod.4c00857

Molecular dissection of the chromosome partitioning protein RocS and regulation by phosphorylation

Autori: Margaux Demuysere, Adrien Ducret, Christophe Grangeasse
Pubblicato in: Journal of Bacteriology, Numero 206, 2024, ISSN 0021-9193
Editore: American Society for Microbiology
DOI: 10.1128/jb.00291-24

Bad to the bone? – Genomic analysis of Enterococcus isolates from diverse environments reveals that most are safe and display potential as food fermentation microorganisms

Autori: Belay Tilahun Tadesse, Ema Svetlicic, Shuangqing Zhao, Nega Berhane, Carsten Jers, Christian Solem, Ivan Mijakovic
Pubblicato in: Microbiological Research, Numero 283, 2024, Pagina/e 127702, ISSN 0944-5013
Editore: Elsevier BV
DOI: 10.1016/j.micres.2024.127702

Pleomorphic Variants of Borreliella (syn. Borrelia) burgdorferi Express Evolutionary Distinct Transcriptomes

Autori: Nina Čorak, Sirli Anniko, Christina Daschkin-Steinborn, Viktoria Krey, Sara Koska, Momir Futo, Tin Široki, Innokenty Woichansky, Luka Opašić, Domagoj Kifer, Anja Tušar, Horst-Günter Maxeiner, Mirjana Domazet-Lošo, Carsten Nicolaus, Tomislav Domazet-Lošo
Pubblicato in: International Journal of Molecular Sciences, Numero 24, 2025, Pagina/e 5594, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24065594

High mobility graphene field effect transistors on flexible EVA/PET foils

Autori: Munis Khan, Jie Ji, Binbin Zhou, Peter U Jepsen, Peter Boggild, August Yurgens
Pubblicato in: 2D Materials, Numero 11, 2024, Pagina/e 035022, ISSN 2053-1583
Editore: 2D Materials
DOI: 10.1088/2053-1583/ad4b36

A novel time-lapse imaging method for studying developing bacterial biofilms

Autori: Momir Futo; Tin Široki; Sara Koska; Nina Čorak; Anja Tušar; Mirjana Domazet-Lošo; Tomislav Domazet-Lošo
Pubblicato in: Crossref, Numero 1, 2023, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-022-24431-y

Advanced Nanomaterials for Cancer Therapy: Gold, Silver, and Iron Oxide Nanoparticles in Oncological Applications

Autori: Priyanka Singh, Santosh Pandit, Sri Renukadevi Balusamy, Mukil Madhusudanan, Hina Singh, H. Mohamed Amsath Haseef, Ivan Mijakovic
Pubblicato in: Advanced Healthcare Materials, 2024, ISSN 2192-2640
Editore: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202403059

Graphene thermocouple fabricated on a flexible and transparent substrate

Autori: Youngwoo Nam, Daewon Gu, Munis Khan, August Yurgens
Pubblicato in: AIP Advances, Numero 14, 2024, ISSN 2158-3226
Editore: American Institute of Physics Inc.
DOI: 10.1063/5.0203178

Genomic characterization and assessment of pathogenic potential of Legionella spp. isolates from environmental monitoring

Autori: Ema Svetlicic, Daniel Jaén-Luchoro, Roberta Sauerborn Klobucar, Carsten Jers, Snjezana Kazazic, Damjan Franjevic, Goran Klobucar, Brian G. Shelton and Ivan Mijakovic*
Pubblicato in: Frontiers in Microbiology, 2023, ISSN 1664-302X
Editore: Frontiers Media
DOI: 10.3389/fmicb.2022.1091964

Biomimetic Antibacterial Gelatin Hydrogels with Multifunctional Properties for Biomedical Applications

Autori: Hengzhi Ruan, Marko Bek, Santosh Pandit, Alexandra Aulova, Jian Zhang, Philip Bjellheim, Martin Lovmar, Ivan Mijakovic, Roland Kádár
Pubblicato in: ACS Applied Materials & Interfaces, Numero 15, 2023, Pagina/e 54249-54265, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.3c10477

CHAMP delivers accurate taxonomic profiles of the prokaryotes, eukaryotes, and bacteriophages in the human microbiome

Autori: Sara Pita, Pernille Neve Myers, Joachim Johansen, Jakob Russel, Mads Cort Nielsen, Aron C. Eklund, Henrik Bjørn Nielsen
Pubblicato in: Frontiers in Microbiology, Numero 15, 2024, ISSN 1664-302X
Editore: Frontiers Media
DOI: 10.3389/fmicb.2024.1425489

An integrated workflow for enhanced taxonomic and functional coverage of the mouse fecal metaproteome

Autori: Nicolas Nalpas, Lesley Hoyles, Viktoria Anselm, Tariq Ganief, Laura Martinez-GiliORCID Icon, Cristina Grau, Irina Droste-Borel, Laetitia Davidovic, Xavier Altafaj, Marc-Emmanuel Dumas & Boris Macek
Pubblicato in: Gut Microbes, Numero 19490976, 2021, ISSN 1949-0976
Editore: Landes Bioscience
DOI: 10.1080/19490976.2021.1994836

Achieving Long‐Range Arbitrary Uniform Alignment of Nanostructures in Magnetic Fields

Autori: Viney Ghai, Santosh Pandit, Magnus Svensso, Ragnar Larsson, Aleksandar Matic, Roselle Ngaloy, Saroj P. Dash, Ann Terry, Kim Nygård, Ivan Mijakovic, Roland Kádár
Pubblicato in: Advanced Functional Materials, 2024, ISSN 1616-301X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202406875

3D printed inserts for reproducible high throughput screening of cell migration

Autori: Abhayraj S. Joshi, Mukil Madhusudanan, Ivan Mijakovic
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 11, 2023, ISSN 2296-634X
Editore: Frontiers
DOI: 10.3389/fcell.2023.1256250

Other (2)

E. coli Toxin YjjJ (HipH) Is a Ser/Thr Protein Kinase That Impacts Cell Division, Carbon Metabolism, and Ribosome Assembly

Autori: Fabio Lino Gratani, Till Englert, Payal Nashier, Peter Sass, Laura Czech, Niels Neumann, Sofia Doello, Petra Mann, Rudolf Blobelt, Siegfried Alberti, Karl Forchhammer, Gert Bange , Katharina Höfer, Boris Macek
Pubblicato in: 2022
Editore: ASM Journals
DOI: 10.1128/msystems.01043-22

Identifying Novel Determinants of Bacterial Pathogenicity using Phylogenetic-based Orthology Analysis

Autori: RIBEIRO, Sara
Pubblicato in: Numero 1, 2024
Editore: Zenodo
DOI: 10.5281/zenodo.13694408