Objective
The project aims to exploit the very high reducing power of hyperthermophilic microorganisms for the on-line production of baldheads, (choral) alcohols as well as for the selective reduction of double bonds for a range of industrial applications. The metabolic and genetic diversity of Thermococcales, including pyrococcus and Thermococcus spp. will be exploited by screening available strain collections for specific bio-reducing capacities, as well as the three established Pyrococcus genomes for enzymes catalysing the reductive conversions via genome and protease based approaches. Further development of genetic tools will allow for optimising the in vivo bio reductions at 50-100 °C by metabolic engineering to prevent side reactions. Fermentation conditions and reactor design will be optimised, and on-line product distillation established. Finally, a novel, stable co-factor regenerating system will be applied to the in vitro bio-reduction system.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- engineering and technology industrial biotechnology metabolic engineering
- natural sciences chemical sciences organic chemistry alcohols
- natural sciences biological sciences genetics genomes
- natural sciences biological sciences microbiology
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
6700 EV WAGENINGEN
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.