Investigating Host-Microbial Interactions after Bariatric Surgery

Lipid profiling of mouse intestinal organoids for studying <i>APC</i> mutations

Author(s): Zoë Jukes, Anne Freier, Maria Glymenaki, Richard Brown, Lee Parry, Elizabeth Want, Panagiotis A. Vorkas, Jia V. Li
Published in: Bioscience Reports, Issue 41, 2021, ISSN 0144-8463
Publisher: Kluwer Academic Publishers
DOI: 10.1042/bsr20202915

Chronic treatment with glucagon-like peptide-1 and glucagon receptor co-agonist causes weight loss-independent improvements in hepatic steatosis in mice with diet-induced obesity

Author(s): Emma Rose McGlone, David C.D. Hope, Iona Davies, Marian Dore, Rob Goldin, Ben Jones, Zhigang Liu, Jia V. Li, Panagiotis A. Vorkas, Bernard Khoo, David Carling, James Minnion, Stephen R. Bloom, Tricia M-M. Tan
Published in: Biomedicine & Pharmacotherapy, Issue 176, 2024, Page(s) 116888, ISSN 0753-3322
Publisher: Elsevier Masson
DOI: 10.1016/j.biopha.2024.116888

Tumour Necrosis Factor-Alpha (TNF-α)-Induced Metastatic Phenotype in Colorectal Cancer Epithelial Cells: Mechanistic Support for the Role of MicroRNA-21

Author(s): Aminah G. Alotaibi, Jia V. Li, Nigel J. Gooderham
Published in: Cancers, Issue 15, 2025, Page(s) 627, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15030627

Roux-en-Y gastric bypass-associated fecal tyramine promotes colon cancer risk via increased DNA damage, cell proliferation, and inflammation

Author(s): Maria Glymenaki, Sophie Curio, Smeeta Shrestha, Qi Zhong, Laura Rushton, Rachael Barry, Mona El-Bahrawy, Julian R. Marchesi, Yulan Wang, Nigel J. Gooderham, Nadia Guerra, Jia V. Li
Published in: Microbiome, Issue 13, 2025, ISSN 2049-2618
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/s40168-025-02049-2

Rectal swabs as a viable alternative to faecal sampling for the analysis of gut microbiota functionality and composition

Author(s): Shiva T. Radhakrishnan, Kate I. Gallagher, Benjamin H. Mullish, Jose I. Serrano-Contreras, James L. Alexander, Jesus Miguens Blanco, Nathan P. Danckert, Maria Valdivia-Garcia, Billy J. Hopkins, Anik Ghai, Azad Ayub, Jia V. Li, Julian R. Marchesi, Horace R. T. Williams
Published in: Scientific Reports, Issue 13, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-27131-9

Improved Quantitation of Short-Chain Carboxylic Acids in Human Biofluids Using 3-Nitrophenylhydrazine Derivatization and Liquid Chromatography with Tandem Mass Spectrometry (LC-MS/MS)

Author(s): Maria Valdivia-Garcia, Katie Chappell, Stephane Camuzeaux, Lucía Olmo-García, Verena Horneffer-van der Sluis, Shiva T. Radhakrishnan, Hannah Stephens, Sonia Bouri, Lucia M. de Campos Braz, Horace R.T. Williams, Mathew R. Lewis, Gary Frost, Jia V. Li
Published in: SSRN Electronic Journal, 2023, ISSN 1556-5068
Publisher: Elsevier BV
DOI: 10.2139/ssrn.4163686

Differential effects of L‐ and D‐phenylalanine on pancreatic and gastrointestinal hormone release in humans: A randomized crossover study

Author(s): Anjali Amin, James Frampton, Zhigang Liu, Georgia Franco‐Becker, Mariana Norton, Aos Alaa, Jia V. Li, Kevin G. Murphy
Published in: Diabetes, Obesity and Metabolism, Issue 23, 2024, Page(s) 147-157, ISSN 1462-8902
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/dom.14204

Roux-en-Y gastric bypass surgery in Zucker rats induces bacterial and systemic metabolic changes independent of caloric restriction-induced weight loss

Author(s): Florian Seyfried, Jutarop Phetcharaburanin, Maria Glymenaki, Arno Nordbeck, Mohammed Hankir, Jeremy K Nicholson, Elaine Holmes, Julian R. Marchesi, Jia V. Li
Published in: Gut Microbes, Issue 13, 2025, ISSN 1949-0976
Publisher: Landes Bioscience
DOI: 10.1080/19490976.2021.1875108

Multiomic features associated with mucosal healing and inflammation in paediatric Crohn’s disease

Author(s): Henry Taylor, Jose Ivan Serrano‐Contreras, Julie A. K. McDonald, Jenny Epstein, JM Fell, Rocio C. Seoane, Jia V. Li, Julian R. Marchesi, Ailsa L. Hart
Published in: Alimentary Pharmacology & Therapeutics, Issue 52, 2023, Page(s) 1491-1502, ISSN 0269-2813
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/apt.16086

Indole-3-Aldehyde Reduces Inflammatory Responses and Restores Intestinal Epithelial Barrier Function Partially via Aryl Hydrocarbon Receptor (AhR) in Experimental Colitis Models

Author(s): Mu Wang, Jian Guo, Ailsa L Hart, Jia V Li
Published in: Journal of Inflammation Research, Issue Volume 16, 2023, Page(s) 5845-5864, ISSN 1178-7031
Publisher: Dove Medical Press Ltd
DOI: 10.2147/jir.s432747

The Metabolomic Effects of Tripeptide Gut Hormone Infusion Compared to Roux-en-Y Gastric Bypass and Caloric Restriction

Author(s): Ben Jones, Caroline Sands, Kleopatra Alexiadou, James Minnion, George Tharakan, Preeshila Behary, Ahmed R Ahmed, Sanjay Purkayastha, Matthew R Lewis, Stephen Bloom, Jia V Li, Tricia M Tan
Published in: The Journal of Clinical Endocrinology & Metabolism, Issue 107, 2024, Page(s) e767-e782, ISSN 0021-972X
Publisher: The Endocrine Society
DOI: 10.1210/clinem/dgab608

Derivatization to reduce background interferences for simultaneous quantitation of trimethylamine (TMA) and trimethylamine-N-oxide (TMAO) using liquid chromatography with tandem mass spectrometry

Author(s): Maria A. Valdivia-Garcia, Yang Bi, Kaoutar Abaakil, Jia V Li
Published in: Journal of Pharmaceutical and Biomedical Analysis, Issue 252, 2024, Page(s) 116480, ISSN 0731-7085
Publisher: Elsevier BV
DOI: 10.1016/j.jpba.2024.116480

Stability in fecal metabolites amid a diverse gut microbiome composition: a one-month longitudinal study of variability in healthy individuals

Author(s): Matteo Sangermani, Indri Desiati, Solveig M. Jørgensen, Jia V. Li, Trygve Andreassen, Tone F. Bathen, Guro F. Giskeødegård
Published in: Gut Microbes, Issue 16, 2024, ISSN 1949-0976
Publisher: Landes Bioscience
DOI: 10.1080/19490976.2024.2427878

The double burden of malnutrition in individuals: Identifying key challenges and re‐thinking research focus

Author(s): Agklinta Kiosia, Aygul Dagbasi, James A. Berkley, John P. H. Wilding, Andrew J. Prendergast, Jia V. Li, Jon Swann, John C. Mathers, Marko Kerac, Douglas Morrison, Lesley Drake, Andre Briend, Kathryn Maitland, Gary Frost
Published in: Nutrition Bulletin, Issue 49, 2024, Page(s) 132-145, ISSN 1471-9827
Publisher: Wiley
DOI: 10.1111/nbu.12670

Effects of Vancomycin and Ciprofloxacin on the NMRI Mouse Metabolism

Author(s): Zhigang Liu, Bing Xia, Jasmina Saric, Jürg Utzinger, Elaine Holmes, Jennifer Keiser, Jia V. Li
Published in: Journal of Proteome Research, Issue 17/10, 2018, Page(s) 3565-3573, ISSN 1535-3893
Publisher: American Chemical Society
DOI: 10.1021/acs.jproteome.8b00583

Inhibiting Growth of Clostridioides difficile by Restoring Valerate, Produced by the Intestinal Microbiota

Author(s): Julie A.K. McDonald, Benjamin H. Mullish, Alexandros Pechlivanis, Zhigang Liu, Jerusa Brignardello, Dina Kao, Elaine Holmes, Jia V. Li, Thomas B. Clarke, Mark R. Thursz, Julian R. Marchesi
Published in: Gastroenterology, Issue 155/5, 2018, Page(s) 1495-1507.e15, ISSN 0016-5085
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1053/j.gastro.2018.07.014

Differences in Fecal Gut Microbiota, Short-Chain Fatty Acids and Bile Acids Link Colorectal Cancer Risk to Dietary Changes Associated with Urbanization Among Zimbabweans

Author(s): L. Katsidzira, S. Ocvirk, A. Wilson, J. Li, C. B. Mahachi, D. Soni, J. DeLany, J. K. Nicholson, E. G. Zoetendal, S. J. D. O’Keefe
Published in: Nutrition and Cancer, Issue 71/8, 2019, Page(s) 1313-1324, ISSN 0163-5581
Publisher: Lawrence Erlbaum Associates Inc.
DOI: 10.1080/01635581.2019.1602659

Longitudinal metabolic and gut bacterial profiling of pregnant women with previous bariatric surgery

Author(s): Kiana Ashley West, Chidimma Kanu, Tanya Maric, Julie Anne Kathryn McDonald, Jeremy K Nicholson, Jia V Li, Mark R Johnson, Elaine Holmes, Makrina D Savvidou
Published in: Gut, 2020, Page(s) gutjnl-2019-319620, ISSN 0017-5749
Publisher: BMJ Publishing Group
DOI: 10.1136/gutjnl-2019-319620

Post-operative delirium associated with metabolic alterations following hemi-arthroplasty in older patients

Author(s): Yong Guo, Yingchuan Li, Yinan Zhang, Shudong Fang, Xiaotao Xu, Aihua Zhao, Junfeng Zhang, Jia V Li, Daqing Ma, Wei Jia, Wei Jiang
Published in: Age and Ageing, Issue 49/1, 2019, Page(s) 88-95, ISSN 0002-0729
Publisher: Oxford University Press
DOI: 10.1093/ageing/afz132

A biochemical comparison of the lung, colonic, brain, renal, and ovarian cancer cell lines using 1H-NMR spectroscopy

Author(s): Cong Hu, Zhigang Liu, Hailin Zhao, Lingzhi Wu, Qingquan Lian, Daqing Ma, Jia V. Li
Published in: Bioscience Reports, Issue 40/4, 2020, ISSN 0144-8463
Publisher: Kluwer Academic Publishers
DOI: 10.1042/bsr20194027

Microbiota- and Radiotherapy-Induced Gastrointestinal Side-Effects (MARS) Study: A Large Pilot Study of the Microbiome in Acute and Late-Radiation Enteropathy

Author(s): Miguel Reis Ferreira, H. Jervoise N. Andreyev, Kabir Mohammed, Lesley Truelove, Sharon M. Gowan, Jia Li, Sarah L. Gulliford, Julian R. Marchesi, David P. Dearnaley
Published in: Clinical Cancer Research, Issue 25/21, 2019, Page(s) 6487-6500, ISSN 1078-0432
Publisher: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-19-0960

In vitro metabolomic footprint of the Echinococcus multilocularis metacestode

Author(s): Dominic Ritler, Reto Rufener, Jia V. Li, Urs Kämpfer, Joachim Müller, Claudia Bühr, Stefan Schürch, Britta Lundström-Stadelmann
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-56073-y

Evaluation of Direct from Sample Metabolomics of Human Feces Using Rapid Evaporative Ionization Mass Spectrometry

Author(s): Simon J. S. Cameron, James L. Alexander, Frances Bolt, Adam Burke, Hutan Ashrafian, Julian Teare, Julian R. Marchesi, James Kinross, Jia V. Li, Zoltán Takáts
Published in: Analytical Chemistry, Issue 91/21, 2019, Page(s) 13448-13457, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.9b02358

A prospective cohort analysis of gut microbial co-metabolism in Alaska Native and rural African people at high and low risk of colorectal cancer

Author(s): Soeren Ocvirk, Annette S Wilson, Joram M Posma, Jia V Li, Kathryn R Koller, Gretchen M Day, Christie A Flanagan, Jill Evon Otto, Pam E Sacco, Frank D Sacco, Flora R Sapp, Amy S Wilson, Keith Newton, Faye Brouard, James P DeLany, Marissa Behnning, Corynn N Appolonia, Devavrata Soni, Faheem Bhatti, Barbara Methé, Adam Fitch, Alison Morris, H Rex Gaskins, James Kinross, Jeremy K Nicholson, Timothy K
Published in: The American Journal of Clinical Nutrition, Issue 111/2, 2019, Page(s) 406-419, ISSN 0002-9165
Publisher: American Society for Clinical Nutrition, Inc.
DOI: 10.1093/ajcn/nqz301

Monosodium Glutamate (MSG) Renders Alkalinizing Properties and Its Urinary Metabolic Markers of MSG Consumption in Rats

Author(s): Nahok, Li, Phetcharaburanin, Abdul, Wongkham, Thanan, Silsirivanit, Anutrakulchai, Selmi, Cha’on
Published in: Biomolecules, Issue 9/10, 2019, Page(s) 542, ISSN 2218-273X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/biom9100542

Bile salt metabolism is not the only factor contributing to Clostridioides ( Clostridium ) difficile disease severity in the murine model of disease

Author(s): Caitlin A. Jukes, Umer Zeeshan Ijaz, Anthony Buckley, Janice Spencer, June Irvine, Denise Candlish, Jia V. Li, Julian R. Marchesi, Gillian Douce
Published in: Gut Microbes, Issue 11/3, 2020, Page(s) 481-496, ISSN 1949-0976
Publisher: Landes Bioscience
DOI: 10.1080/19490976.2019.1678996

Sevoflurane but not propofol enhances ovarian cancer cell biology through regulating cellular metabolic and signaling mechanisms

Author(s): Cong Hu, Bincheng Wang, Zhigang Liu, Qiling Chen, Masashi Ishikawa, Han Lin, Qingquan Lian, Jun Li, Jia V. Li, Daqing Ma, null null
Published in: Cell Biology and Toxicology, Issue 39, 2023, Page(s) 1395-1411, ISSN 0742-2091
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10565-022-09766-6

Improved Spatial Resolution of Metabolites in Tissue Biopsies Using High-Resolution Magic-Angle-Spinning Slice Localization NMR Spectroscopy

Author(s): Elisabeth V. Vonhof, Martial Piotto, Elaine Holmes, John C. Lindon, Jeremy K. Nicholson, Jia V. Li
Published in: Analytical Chemistry, Issue 92, 2023, Page(s) 11516-11519, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.0c02377

Tumour necrosis factor-α (TNF-α) enhances dietary carcinogen-induced DNA damage in colorectal cancer epithelial cells through activation of JNK signaling pathway

Author(s): Aminah G. Alotaibi, Jia V. Li, Nigel J. Gooderham
Published in: Toxicology, Issue 457, 2022, Page(s) 152806, ISSN 0300-483X
Publisher: Elsevier BV
DOI: 10.1016/j.tox.2021.152806

Roux-en-Y gastric bypass-induced bacterial perturbation contributes to altered host-bacterial co-metabolic phenotype

Author(s): Jia V. Li, Hutan Ashrafian, Magali Sarafian, Daniel Homola, Laura Rushton, Grace Barker, Paula Momo Cabrera, Matthew R. Lewis, Ara Darzi, Edward Lin, Nana Adwoa Gletsu-Miller, Stephen L. Atkin, Thozhukat Sathyapalan, Nigel J. Gooderham, Jeremy K. Nicholson, Julian R. Marchesi, Thanos Athanasiou, Elaine Holmes
Published in: Microbiome, Issue 9, 2021, ISSN 2049-2618
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/s40168-021-01086-x

Metabolic Profiling in IBD

Author(s): Maria Glymenaki, Jia V. Li, Julian R. Marchesi
Published in: Biomarkers in Inflammatory Bowel Diseases, 2019, Page(s) 303-312, ISBN 978-3-030-11445-9
Publisher: Springer International Publishing
DOI: 10.1007/978-3-030-11446-6_25

Diet changes due to urbanization in South Africa are linked to microbiome and metabolome signatures of Westernization and colorectal cancer

Author(s): M. C. Ramaboli, S. Ocvirk, M. Khan Mirzaei, B. L. Eberhart, M. Valdivia-Garcia, A. Metwaly, K. Neuhaus, G. Barker, J. Ru, L. T. Nesengani, D. Mahdi-Joest, A. S. Wilson, S. K. Joni, D. C. Layman, J. Zheng, R. Mandal, Q. Chen, M. R. Perez, S. Fortuin, B. Gaunt, D. Wishart, B. Methé, D. Haller, J. V. Li, L. Deng, R. Swart, S. J. D. O’Keefe
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-46265-0

Investigating the metabolic function of the gut microbiota in colorectal carcinogenesis via choline metabolism

Author(s): Yang Bi
Published in: 2024
Publisher: Imperial College London

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