Obiettivo The aim of this project is to assess the facilitators and barriers to scale-up of two proven active TB case finding and comprehensive patient care models in Vietnam and Nepal as examples of these low and lower-middle income country settings. We will use these data to develop an evidence-based framework for scale-up of implementation by the respective National TB Programs in consultation with relevant stakeholders and governments. This will facilitate programmatic adoption of realistic and optimised active case finding strategies by national TB control programmes.We will compare two alternative implementation strategies in each country appropriate to the local level of current service delivery. For Vietnam, we will compare implementation using salaried employees with volunteer counsellors. For Nepal, we will compare two diagnostic testing strategies as a component of active case finding: traditional smear microscopy or the novel Xpert Omni molecular testing. We will determine the health economic impact of active case detection under the different models and model the long-term epidemiologic impact and cost-effectiveness.The research seeks to achieve the following objectives:1) Implementation of active case finding with comprehensive patient support in 6 districts of Ho Chi Minh City, Vietnam detecting 1,450 additional cases in 2 years.2) Implementation of active case finding with comprehensive patient support in 4 districts of the Central Development Region of Nepal, detecting 1,050 additional cases in 2 years.3) Health economic evaluation of alternative implementation models in low (Nepal) and middle income (Vietnam) scenarios to inform policy.4) Consultation with policy makers, stakeholders and end-users to evaluate facillatators and barriers to scale-up at health system and individual level and development of an evidence-based framework for scale-up for each country.5) Transmission modelling of epidemic impact and long-term cost-effectiveness. Campo scientifico social scienceseconomics and businesseconomicshealth economicseconomic impact of epidemics Programma(i) H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme H2020-EU.3.1.6. - Health care provision and integrated care Argomento(i) SC1-PM-21-2016 - Implementation research for scaling-up of evidence based innovations and good practice in Europe and low- and middle-income countries Invito a presentare proposte H2020-SC1-2016-2017 Vedi altri progetti per questo bando Bando secondario H2020-SC1-2016-RTD Meccanismo di finanziamento RIA - Research and Innovation action Coordinatore LIVERPOOL SCHOOL OF TROPICAL MEDICINE Contribution nette de l'UE € 1 225 000,00 Indirizzo PEMBROKE PLACE L35QA LIVERPOOL 3 Regno Unito Mostra sulla mappa Regione North West (England) Merseyside Liverpool Tipo di attività Higher or Secondary Education Establishments Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 1 225 000,00 Partecipanti (4) Classifica in ordine alfabetico Classifica per Contributo netto dell'UE Espandi tutto Riduci tutto FREUNDESKREIS FUR INTERNATIONALE TUBERKULOSEHILFE EV Germania Contribution nette de l'UE € 1 524 026,25 Indirizzo HUGELSTRASSE 4 82166 GRAFELFING Mostra sulla mappa Regione Bayern Oberbayern München, Landkreis Tipo di attività Other Collegamenti Contatta l’organizzazione Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 1 524 026,25 BIRAT NEPAL MEDICAL TRUST Nepal Contribution nette de l'UE € 1 022 995,00 Indirizzo LAZIMPAT KATHMANDU WARD N 2 20564 KATHMANDU Mostra sulla mappa Tipo di attività Other Collegamenti Contatta l’organizzazione Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 1 022 995,00 KAROLINSKA INSTITUTET Svezia Contribution nette de l'UE € 646 563,75 Indirizzo Nobels Vag 5 17177 Stockholm Mostra sulla mappa Regione Östra Sverige Stockholm Stockholms län Tipo di attività Higher or Secondary Education Establishments Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 646 563,75 KONINKLIJKE NEDERLANDSE CENTRALE VERENIGING TOT BESTRIJDING DER TUBERCULOSE (KNCV) Paesi Bassi Contribution nette de l'UE € 493 838,75 Indirizzo MAANWEG 174 2516 AB 's-Gravenhage (Den Haag) Mostra sulla mappa PMI L’organizzazione si è definita una PMI (piccola e media impresa) al momento della firma dell’accordo di sovvenzione. Sì Regione West-Nederland Zuid-Holland Agglomeratie ’s-Gravenhage Tipo di attività Other Collegamenti Contatta l’organizzazione Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 493 838,75
