Objective
The prevalence of diabetes is continuously rising even in low-income economies. Therefore, blood glucose monitoring tools are in high social demand globally. Uninterrupted monitoring of blood glucose is a must in order to keep the fatal levels of glycated hemoglobin under control and to improve the quality of life for diabetic patients. However, glucose monitoring is compromised by the painful finger pricking about 4-5 times a day to obtain blood samples which leads to patient non-compliance and hence endangering their lifes.
The main objective of NANOTEARS is the development of a non-invasive diabetes diagnostic tool by detecting in vitro ocular glucose that is ready to be integrated in a smartphone for point of care and homecare use. Compared to other body fluids, tears are more accessible than blood or interstitial fluid, more continuously obtainable, and less susceptible to dilution. So, it is a worthwhile alternative to finger pricking for repetitive monitoring. Additionally, the use of a cell phone enables systematically collection and management of glucose level records in electronic form in order to reduce medical errors and improve quality of care and promote evidence-based medicine.
Our sensing strategy is based on the use of fluorescent spectroscopy. Taking into account, that glucose concentration in tear fluid is about 50-100 lower than the glucose in blood there is a need to enhace the emitted signal to meet the accuracy and tolerance as recommended in the ISO 15197:2013. To reach this goal, we will fabricate highly fluorescent nanocomposite consisting of functionalized carbon quantum dots embedded into mesoporous silica. The entire synthesis will be performed without the need to use residual chemical precursors and stabilizers allowing for “green synthesis”, owing to the use laser ablation in liquids. The use of femtosecond disruptive technology will enable to circumvent the limitations imposed by the low speeds at which nanoparticles are ablated.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences clinical medicine endocrinology diabetes
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
- engineering and technology electrical engineering, electronic engineering, information engineering information engineering telecommunications mobile phones
- engineering and technology nanotechnology nano-materials
- natural sciences physical sciences optics spectroscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2016
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
12006 Castellon De La Plana
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.