Integrated Microfluidic System for Long-Term Cell Cultivation, Monitoring and Analysis

Informacje na temat projektu

BIOCELLCHIP

Identyfikator umowy o grant: 300121

Projekt został zamknięty

Data rozpoczęcia 1 Marca 2013

Data zakończenia 29 Lutego 2016

Finansowanie w ramach

• Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Koszt całkowity € 238 962,30

Wkład UE € 238 962,30

Koordynowany przez

VILNIAUS UNIVERSITETAS
Lithuania

Cel

A wide range of microfluidic systems are emerging as powerful tools for various studies in physics, chemistry and biology. Due to their unique liquid handling capabilities, outstanding analytical performance, miniaturization and automation microfluidics have attracted a special attention among biomedicine and biological disciplines. For cell-based assays in particular, this new technology can bring an unprecedented level of control over single-cells and their populations, provide precise control of cellular microenvironments and enable typical laboratory operations using only minute amounts of samples. However, despite these exciting promises, the vast majority of cell-based microfluidic devices available today are still in the proof-of-concept state. Accordingly, there is a growing demand for microfluidic systems that support long-term cell growth in well-controlled conditions and allow reproducible and sequential multi-step operations in an automated fashion. This project is aiming to fulfill these needs through the development of an integrated microfluidic device consisting of multiple individual bioreactors, which will allow single-cell entrapment, cultivation, monitoring and analysis under strictly controlled conditions and long periods of time. By utilizing the developed system with genetically identical yeast cells we will investigate how epigenetic and genetic factors interact to enhance the adaptation process and how the adapted state is maintained in populations. The multidisciplinary approach of this project will make it possible to tackle these and other questions in a quantitative and systematic way. The results of this work should improve our basic understanding of the relationship between genetic and epigenetic inheritance systems and their role in the evolution of organisms, while the integrated microfluidic platform we will develop during this fellowship will undoubtedly find a myriad of applications in fundamental and applied biological sciences.

Dziedzina nauki (EuroSciVoc)

Klasyfikacja projektów w serwisie CORDIS opiera się na wielojęzycznej taksonomii EuroSciVoc, obejmującej wszystkie dziedziny nauki, w oparciu o półautomatyczny proces bazujący na technikach przetwarzania języka naturalnego. Więcej informacji: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc

• nauki przyrodnicze › nauki fizyczne › mechanika klasyczna › mechanika płynów › microfluidics
• inżynieria i technologia › biotechnologia środowiska › bioremediacja › bioreaktor
• nauki przyrodnicze › nauki biologiczne
• nauki społeczne › socjologia › stosunki przemysłowe › automatyzacja

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Program(-y)

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Temat(-y)

• FP7-PEOPLE-2011-IOF - Marie Curie Action: "International Outgoing Fellowships for Career Development"

Zaproszenie do składania wniosków

FP7-PEOPLE-2011-IOF
Zobacz inne projekty w ramach tego zaproszenia

System finansowania

MC-IOF - International Outgoing Fellowships (IOF)

Koordynator

VILNIAUS UNIVERSITETAS

• Wkład UE: € 238 962,30
• Adres: UNIVERSITETO G. 3 ; 01513 Vilnius ; Litwa
• Region: Lietuva › Sostinės regionas › Vilniaus apskritis
• Rodzaj działalności: Higher or Secondary Education Establishments
• Koszt całkowity: Brak danych