WP1. Construction of the industrial plant
Once the new production plant was constructed (1,500m2) for microalgae production, different technical trials were carried out during the start-up of the plant. At the end of the project NEOALGAE had organized an open day with the objective of showing the industrial plant and the project
WP2 Industrial scale-up of the bio-production of Omega-3 and Astaxanthin
Different experimental set-ups were conducted by NEOALGAE for the microalgae species, the scaling-up were performed, with good productivity results. Finally, stress induction allowed to increase the of Omega3 and astaxanthin, that was extracted and purified with CO2 supercritical technology.
In vitro analysis were carried out to test the efficacy of the omega-3 and Astaxanthin oils and to check the safety.
WP3 Design and industrial scale up process for Bicomega3 and Bicoxanthin
BICOSOME used algae extracts rich in Astaxanthin and Omega 3 to develop two prototypes, one per each bioactive, which complied with stability and formulation standards. A production method was developed for these prototypes, the specification parameters were determined and pilot and scale-up productions were carried out.
WP 4 Safety, efficacy and acceptance of compounds
The Bicomega3 and Bicoxanthin were tested in order to assure they were safe, effective and acceptable by the users:
- The safety in vitro tests and in vivo tests proved that are safe for topical use.
- The to efficacy in vitro tests showed anti-inflammatory activity in Bicomega3 and protection pollutant factor for Bicoxanthin
- The anti-ageing test showed that both can prevent ageing.
- Both are technically ready to be commercialized.
WP 5 IPR, commercialisation strategy and business relevance
NEOALGAE has implemented an IPR strategy with patents and registration of trademarks and food supplements, has developed the Strategic Plan 2020, organized meetings with investors and had participated in different investment forums.
BICOSOME has protected the brand Bicoalgae® and the names BICOALGAE® ⍵3 and BICOALGAE® XT. They will be commercialized to Cosmetic and Dermopharmaceutical companies in a B2B. Neoalgae will sell to BICOSOME the extracts (a price per kg has been proposed for the extracts and the companies are negotiating a supply agreement).
WP 6 Communication and dissemination
Diffusion and communication was addressed trough several activities and using different tools, being the final goal was to achieve public awareness about all related to the project as well as spreading the SME Instrument funding: Social media, trade fairs, press media, final event (open days)
BICOSOME has set a Communication and dissemination plan for the launching of Bicoalgae®, including the presence in at least 6 international fairs in 2019. Several scientific articles are being prepared to Cosmetic magazines as described
