CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.
Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .
Rezultaty
Final press release with summary on the general project progress and main findings will be published
First quarterly electronic bulletins online (odnośnik otworzy się w nowym oknie)Publication of the first quarterly electronic bulletin with information on the project progress and first results
Release of project website public and internal part, communication package (logo, flyer, social media announcement (odnośnik otworzy się w nowym oknie)Corporate design eg logo PPT layout flyer and public and internal part of EQIPD website set up to disseminate results to the public
First press release (odnośnik otworzy się w nowym oknie)The first EQIPD press release with general information focusing on the aims of the project as well as the outcomes from the first project meeting will be published
All sites involved in the animal experiments will obtain ethical approval for their experiments
Report factors identified by historical data of published data (odnośnik otworzy się w nowym oknie)A report will be generated that describes the experimental design factors identified from the systematic review of published academic data that affect outcomes
Report on factors that underlie the robustness and generalisability of commonly used assays (odnośnik otworzy się w nowym oknie)A report of the prevalence and impact of factors related to the robustness and generalisability of commonly used assays derived from the analyses of data from members of the consortium of published academic studies
Report on validated guiding principles for robustness and data quality in preclinical Neuroscience and Safety research (odnośnik otworzy się w nowym oknie)Based on the outcome of the harmonisation experiments a report will be generated to provide guiding principles for optimal study design and experimentation
Outcome report from cross site validation (odnośnik otworzy się w nowym oknie)An outcome report on stage 1 of the crosssite validation study localization stage will be generated by the sites involved in the experiments on the basis of the generated data This will involve data summaries statistical analyses and conclusions
Outcome report from harmonized testing (odnośnik otworzy się w nowym oknie)An outcome report on stage 2 of the crosssite validation study harmonisation stage will be generated by the sites involved in the experiments on the basis of the generated data This will involve data summaries statistical analyses and conclusions
Evaluation of existing training modules (odnośnik otworzy się w nowym oknie)Generation of a list of existing training modules on keyprinciples for preclinical robustness and quality including an evaluation of each module against 1 the scope of EQIPD as determined by WPs 2 3 4 5 and 6 and 2 our predefined set of User Specification Requirements USR
With input from WPs 2 and 3 develop harmonized protocols for cross validation testing (odnośnik otworzy się w nowym oknie)Based on input from WPs 2 and 3 the local experimental protocols will be updated in order to perform stage 2 of the crosssite validation studies eg harmonisation
Data sharing procedures beyond EQIPD (odnośnik otworzy się w nowym oknie)A legally valid Data Deposition agreement will be developed to ensure that data depositors have control over whether or not their data can be made public before or after the end of this consortium
Final version of the framework of key principles and criteria for guiding the design, conduct and analysis of preclinical efficacy and safety research (odnośnik otworzy się w nowym oknie)The framework will be reevaluated and refined with the conclusions of the prospective crosssite validation studies performed by WP23 at a second consensus meeting A final guidance will be agreed and then published A process for continuous improvement of the guidance will be agreed
Final version of quality assurance system ready for implementation in industry and academia in non-regulated research (odnośnik otworzy się w nowym oknie)Readytouse set of recommendations addressing the needs of research organizations of different types with the integrated risk assessment and tiered implementation tools
Outcome report from Ring testing (odnośnik otworzy się w nowym oknie)An outcome report on stage 3 of the crosssite validation study Ring testing stage will be generated by the sites involved in the experiments on the basis of the generated data This will involve data summaries statistical analyses and conclusions
A diagram of the EQIPDDWH solution to house all different database structures required for WPs 2 and 4 with appropriate capacity and user rights
Comprehensive, engaging, selection of training materials on scientific quality, hosted on a web-based platform (odnośnik otworzy się w nowym oknie)A Learning Environment has been selected and installed and existing training modules or those newly developed have been collated in the Education section of this Learning Environment utilizing a collection of links to various training modules and have undergone alpha and beta testing
Structure and first incentives for electronic community enabling social learning, hosted on a web-based platform (odnośnik otworzy się w nowym oknie)The social learning Exposure section of the learning environment is populated and live for use including eg electronic bulletins links to existing discussion groups Facebook Twitter LinkedIn
Specifications and a working example of an information exchange protocol will be established to enable errorless and fully transparent communication between office study design assistants electronic lab journals and labbased research software
A transparent protocol for unbiased inclusion of experimental paradigms and data sets required for WPs 2 and 4An ontology for the description of in vivo experiments such as these including quality aspects and working alongside other groups sharing the same ambition and develop a template for the depositing of such work in open access fora such as figshare Our data will be deposited using the template devised
Publikacje
Autorzy:
Anton Bespalov, René Bernard, Anja Gilis, Björn Gerlach, Javier Guillén, Vincent Castagné, Isabel A Lefevre, Fiona Ducrey, Lee Monk, Sandrine Bongiovanni, Bruce Altevogt, María Arroyo-Araujo, Lior Bikovski, Natasja de Bruin, Esmeralda Castaños-Vélez, Alexander Dityatev, Christoph H Emmerich, Raafat Fares, Chantelle Ferland-Beckham, Christelle Froger-Colléaux, Valerie Gailus-Durner, Sabine
Opublikowane w:
eLife, Numer 10, 2021, ISSN 2050-084X
Wydawca:
eLife Sciences Publications
DOI:
10.7554/elife.63294
Autorzy:
Bernhard Voelkl, Naomi S. Altman, Anders Forsman, Wolfgang Forstmeier, Jessica Gurevitch, Ivana Jaric, Natasha A. Karp, Martien J. Kas, Holger Schielzeth, Tom Van de Casteele, Hanno Würbel
Opublikowane w:
Nature Reviews Neuroscience, Numer 21/7, 2020, Strona(/y) 384-393, ISSN 1471-003X
Wydawca:
Nature Publishing Group
DOI:
10.1038/s41583-020-0313-3
Autorzy:
Betül R. Erdogan, Jan Vollert, Martin C. Michel
Opublikowane w:
Naunyn-Schmiedeberg's Arch Pharmacol, Numer 393, 2020, Strona(/y) 1769-1772, ISSN 1432-1912
Wydawca:
Springer
DOI:
10.1007/s00210-020-01926-x
Autorzy:
Jan Vollert, Esther Schenker, Malcolm Macleod, Anton Bespalov, Hanno Wuerbel, Martin Christian Michel, Ulrich Dirnagl, Heidrun Potschka, Kimberley E Wever, Thomas Steckler, Bruce Altevogt, Andrew S C Rice
Opublikowane w:
BMJ Open Science, Numer 2/1, 2018, Strona(/y) e000004, ISSN 2398-8703
Wydawca:
BMJ
DOI:
10.1136/bmjos-2018-000004
Autorzy:
Steckler, T., Macleod, M., Kas, M. J. H., Gilis, A., & Wever, K. E.
Opublikowane w:
Biotechniek, Numer 57 (2), 2018, Strona(/y) 18-23, ISSN 0166-6207
Wydawca:
Stichting Proefdierkundige Informatie
Autorzy:
Harvey J Motulsky, Martin C Michel
Opublikowane w:
British Journal of Pharmacology, Numer 175/18, 2018, Strona(/y) 3636-3637, ISSN 0007-1188
Wydawca:
Wiley-Blackwell
DOI:
10.1111/bph.14441
Autorzy:
Betul R. Erdogan, Irem Karaomerlioglu, Zeynep E. Yesilyurt, Nihal Ozturk, A. Elif Muderrisoglu, Martin C. Michel, Ebru Arioglu-Inan
Opublikowane w:
Naunyn-Schmiedeberg's Archives of Pharmacology, Numer 393/2, 2020, Strona(/y) 243-251, ISSN 0028-1298
Wydawca:
Springer Verlag
DOI:
10.1007/s00210-019-01727-x
Autorzy:
Marjan Amiri, Sandra Murgas, Andreas Stang, Martin C. Michel
Opublikowane w:
Neurourology and Urodynamics, Numer 39/2, 2019, Strona(/y) 754-761, ISSN 0733-2467
Wydawca:
John Wiley & Sons Inc.
DOI:
10.1002/nau.24275
Autorzy:
Anton Bespalov, Thomas Steckler, Phil Skolnick
Opublikowane w:
European Neuropsychopharmacology, Numer 29/12, 2019, Strona(/y) 1312-1320, ISSN 0924-977X
Wydawca:
Elsevier BV
DOI:
10.1016/j.euroneuro.2019.10.007
Autorzy:
Martin C. Michel, T.J. Murphy, Harvey J. Motulsky
Opublikowane w:
Molecular Pharmacology, Numer 97/1, 2019, Strona(/y) 49-60, ISSN 0026-895X
Wydawca:
American Society for Pharmacology and Experimental Therapeutics
DOI:
10.1124/mol.119.118927
Autorzy:
Martin C. Michel, T.J. Murphy, Harvey J. Motulsky
Opublikowane w:
Journal of Pharmacology and Experimental Therapeutics, Numer 372/1, 2019, Strona(/y) 136-147, ISSN 0022-3565
Wydawca:
American Society for Pharmacology and Experimental Therapeutics
DOI:
10.1124/jpet.119.264143
Autorzy:
Martin C. Michel, T.J. Murphy, Harvey J. Motulsky
Opublikowane w:
Drug Metabolism and Disposition, Numer 48/1, 2019, Strona(/y) 64-74, ISSN 0090-9556
Wydawca:
American Society for Pharmacology and Experimental Therapeutics
DOI:
10.1124/dmd.119.090027
Autorzy:
Jan Vollert, Esther Schenker, Malcolm Macleod, Anton Bespalov, Hanno Wuerbel, Martin Michel, Ulrich Dirnagl, Heidrun Potschka, Ann-Marie Waldron, Kimberley Wever, Thomas Steckler, Tom van de Casteele, Bruce Altevogt, Annesha Sil, Andrew S C Rice
Opublikowane w:
BMJ Open Science, Numer 4/1, 2020, Strona(/y) e100046, ISSN 2398-8703
Wydawca:
BMJ
DOI:
10.1136/bmjos-2019-100046
Autorzy:
Annesha Sil, Arina Erfani, Nicola Lamb, Rachel Copland, Gernot Riedel, Bettina Platt
Opublikowane w:
Journal of Alzheimer's Disease (in press currently- preprint online on BioRxiv), 2021
Wydawca:
BioRxiv
DOI:
10.1101/2021.04.29.440396
Autorzy:
Kaitlyn Hair, Juan Pita Almenar, and Emily Sena, on behalf of the EQIPD WP2 study group
Opublikowane w:
Open Science Framework, Numer N/A, 2019, Strona(/y) N/A
Wydawca:
Open Science Framework
Autorzy:
Kaitlyn Hair and Emily Sena, on behalf of the EQIPD WP2 study group
Opublikowane w:
Open Science Framework, Numer N/A, 2019, Strona(/y) N/A
Wydawca:
Open Science Framework
Autorzy:
Isabel A. Lefevre
Opublikowane w:
Invited speaker, 11th World Congress on Alternatives and Animal Use in the Life Science (WC11), Numer Congress postponed to August 2021, abstract published on July 6, 2020, 2020, Strona(/y) p 204
Wydawca:
World Congress on Alternatives and Animal Use in the Life Sciences
Autorzy:
Isabel A. Lefevre, Rita J. Balice-Gordon
Opublikowane w:
Good Research Practice in Non-Clinical Pharmacology and Biomedicine, Numer 257, 2020, Strona(/y) 35-54, ISBN 978-3-030-33655-4
Wydawca:
Springer International Publishing
DOI:
10.1007/164_2019_276
Autorzy:
Betül R. Erdogan, Martin C. Michel
Opublikowane w:
Good Research Practice in Non-Clinical Pharmacology and Biomedicine, Numer 257, 2020, Strona(/y) 163-175, ISBN 978-3-030-33655-4
Wydawca:
Springer International Publishing
DOI:
10.1007/164_2019_283
Autorzy:
Anton Bespalov, Karsten Wicke, Vincent Castagné
Opublikowane w:
Good Research Practice in Non-Clinical Pharmacology and Biomedicine, Numer 257, 2020, Strona(/y) 81-100, ISBN 978-3-030-33655-4
Wydawca:
Springer International Publishing
DOI:
10.1007/164_2019_279
Autorzy:
Javier Guillén, Thomas Steckler
Opublikowane w:
Good Research Practice in Non-Clinical Pharmacology and Biomedicine, Numer 257, 2020, Strona(/y) 367-382, ISBN 978-3-030-33655-4
Wydawca:
Springer International Publishing
DOI:
10.1007/164_2019_292
Autorzy:
Anja Gilis
Opublikowane w:
Good Research Practice in Non-Clinical Pharmacology and Biomedicine, Numer 257, 2020, Strona(/y) 349-365, ISBN 978-3-030-33655-4
Wydawca:
Springer International Publishing
DOI:
10.1007/164_2019_291
Autorzy:
Patrizia Voehringer, Janet R. Nicholson
Opublikowane w:
Good Research Practice in Non-Clinical Pharmacology and Biomedicine, Numer 257, 2020, Strona(/y) 197-222, ISBN 978-3-030-33655-4
Wydawca:
Springer International Publishing
DOI:
10.1007/164_2019_285
Autorzy:
Sandrine Bongiovanni, Robert Purdue, Oleg Kornienko, René Bernard
Opublikowane w:
Good Research Practice in Non-Clinical Pharmacology and Biomedicine, Numer 257, 2020, Strona(/y) 1-17, ISBN 978-3-030-33655-4
Wydawca:
Springer International Publishing
DOI:
10.1007/164_2019_274
Autorzy:
Patricia Kabitzke, Kristin M. Cheng, Bruce Altevogt
Opublikowane w:
Good Research Practice in Non-Clinical Pharmacology and Biomedicine, Numer 257, 2020, Strona(/y) 19-34, ISBN 978-3-030-33655-4
Wydawca:
Springer International Publishing
DOI:
10.1007/164_2019_275
Autorzy:
Wenlong Huang, Nathalie Percie du Sert, Jan Vollert, Andrew S. C. Rice
Opublikowane w:
Good Research Practice in Non-Clinical Pharmacology and Biomedicine, Numer 257, 2020, Strona(/y) 55-69, ISBN 978-3-030-33655-4
Wydawca:
Springer International Publishing
DOI:
10.1007/164_2019_277
Autorzy:
Ulrich Dirnagl
Opublikowane w:
Good Research Practice in Non-Clinical Pharmacology and Biomedicine, Numer 257, 2020, Strona(/y) 71-79, ISBN 978-3-030-33655-4
Wydawca:
Springer International Publishing
DOI:
10.1007/164_2019_278
Autorzy:
Björn Gerlach, Christopher Untucht, Alfred Stefan
Opublikowane w:
Good Research Practice in Non-Clinical Pharmacology and Biomedicine, Numer 257, 2020, Strona(/y) 257-275, ISBN 978-3-030-33655-4
Wydawca:
Springer International Publishing
DOI:
10.1007/164_2019_287
Autorzy:
Malcolm R. Macleod, Ezgi Tanriver-Ayder, Kaitlyn Hair, Emily Sena
Opublikowane w:
Good Research Practice in Non-Clinical Pharmacology and Biomedicine, Numer 257, 2020, Strona(/y) 299-317, ISBN 978-3-030-33655-4
Wydawca:
Springer International Publishing
DOI:
10.1007/164_2019_289
Autorzy:
Malcolm Macleod, Thomas Steckler
Opublikowane w:
Nature, Numer 568/7753, 2019, Strona(/y) 458-458, ISSN 0028-0836
Wydawca:
Nature Publishing Group
DOI:
10.1038/d41586-019-01293-5
Autorzy:
Bespalov A, Michel M, Steckler T (eds.)
Opublikowane w:
Handbook of Experimental Pharmacology, Good Research Practice in Non-Clinical Pharmacology and Biomedicine, Numer 257, 2020, Strona(/y) 1-424, ISBN 978-3-030-33656-1
Wydawca:
Springer
DOI:
10.1007/978-3-030-33656-1
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