Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Science connecting - policy workshop 1

Summary report of the first workshop connecting the scientific objectives of LONGITOOLS and the policy and regulation agendas

Report 7 Updated Dissemination and Communication strategy - LONGITOOLS/EXIMIOUS

Update of Joint dissemination and communication activities for the network.

Findability catalogue

A publicly available metadata of LONGITOOLS cohorts - the metadata will be published on the LONGITOOLS website, the cluster website and CORDIS

Innovation platform

A public event to launch LONGITOOLS innovation platform organised alongside the second General Assembly of LONGITOOLS

LONGITOOLS website

LONGITOOLS website launched

Publikacje

Risk factors for positive and negative COVID-19 tests: a cautious and in- depth analysis of UK biobank data

Autorzy: Marc Chadeau-Hyam, Barbara Bodinier, Joshua Elliott, Matthew D Whitaker, Ioanna Tzoulaki, Roel Vermeulen, Michelle Kelly-Irving, Cyrille Delpierre, Paul Elliott
Opublikowane w: International Journal of Epidemiology, Numer 49(5), 2020, Strona(/y) 1454-1467, ISSN 0300-5771
Wydawca: Oxford University Press
DOI: 10.1093/ije/dyaa134

Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension

Autorzy: Anna Ulrich, Yukyee Wu, Harmen Draisma, John Wharton, Emilia M. Swietlik, Inês Cebola, Eleni Vasilaki, Zhanna Balkhiyarova, Marjo-Riitta Jarvelin, Juha Auvinen, Karl-Heinz Herzig, J. Gerry Coghlan, James Lordan, Colin Church, Luke S. Howard, Joanna Pepke-Zaba, Mark Toshner, Stephen J. Wort, David G. Kiely, Robin Condliffe, Allan Lawrie, Stefan Gräf, Nicholas W. Morrell, Martin R. Wilkins, Inga P
Opublikowane w: Nature Communications, Numer 15, 2024, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-023-44683-0

Variant-specific symptoms of COVID-19 in a study of 1,542,510 adults in England

Autorzy: Whitaker M, Elliott J, Bodinier B, Barclay W, Ward H, Cooke G, Donnelly CA, Chadeau-Hyam M, Elliott P
Opublikowane w: Nature Communications, Numer 13 (6856), 2022, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-022-34244-2

Towards an Interoperable Ecosystem of Research Cohort and Real-world Data Catalogues Enabling Multi-center Studies

Autorzy: Morris Swertz, Esther van Enckevort, José Luis Oliveira, Isabel Fortier, Julie Bergeron, Nicolas H. Thurin, Eleanor Hyde, Alexander Kellmann, Romin Pahoueshnja, Miriam Sturkenboom, Marianne Cunnington, Anne-Marie Nybo Andersen, Yannick Marcon, Gonçalo Gonçalves, Rosa Gini
Opublikowane w: Yearbook of Medical Informatics, Numer 31(01), 2022, Strona(/y) 262-272, ISSN 2364-0502
Wydawca: Thieme Group
DOI: 10.1055/s-0042-1742522

Effects of prenatal exposure to the 1944–45 Dutch famine and glucocorticoid receptor polymorphisms on later life PTSD susceptibility

Autorzy: Kayleigh D Gultig, Susanne R. de Rooij, Charlotte E Hilberdink, Miranda Olff, Tessa J. Roseboom, Mirjam van Zuiden
Opublikowane w: European Journal of Psychotraumatology, Numer 14(2), 2023, Strona(/y) 2219075, ISSN 2000-8066
Wydawca: Taylor & Francis
DOI: 10.1080/20008066.2023.2219075

Epigenome-Wide Meta-analysis Reveals Associations Between Dietary Glycemic Index and Glycemic Load and DNA Methylation in Children and Adolescents of Different Body Sizes

Autorzy: Raffael Ott, Robert Stein, Helena H. Hauta-alus, Justiina Ronkainen, Sílvia Fernández-Barrés, Ulrike Spielau, Holger Kirsten, Tanja Poulain, Phillip E. Melton, Leanne K. Küpers, Hatim Azaryah, Marco Colombo, Kathrin Landgraf, Elmar W. Tobi, Therese O’Sullivan, Rae-Chi Huang, Cristina Campoy, Christiane Winkler, Jesus Vioque, Martine Vrijheid, Wieland Kiess, Antje Körner, Sylvain Sebert, Mar
Opublikowane w: Diabetes Care, Numer 46, 2023, Strona(/y) 2067-2075, ISSN 0149-5992
Wydawca: American Diabetes Association
DOI: 10.2337/dc23-0474

Maternal and infant prediction of the child BMI trajectories; studies across two generations of Northern Finland birth cohorts

Autorzy: Rozenn Nedelec, Jouko Miettunen, Minna Männikkö, Marjo-Riitta Järvelin, Sylvain Sebert
Opublikowane w: International Journal of Obesity, Numer 45/2, 2021, Strona(/y) 404-414, ISSN 0307-0565
Wydawca: Nature Publishing Group
DOI: 10.1038/s41366-020-00695-0

Defining type 2 diabetes polygenic risk scores through colocalization and network-based clustering of metabolic trait genetic associations

Autorzy: Samuel Ghatan; Jeroen van Rooij; Mandy van Hoek; Cindy G. Boer; Janine F. Felix; Maryam Kavousi; Vincent W. Jaddoe; Eric J. G. Sijbrands; Carolina Medina-Gomez; Fernando Rivadeneira; Ling Oei
Opublikowane w: Genome Medicine, Numer 16(1), 2024, Strona(/y) 1-15, ISSN 1756-994X
Wydawca: BioMed Central
DOI: 10.1186/s13073-023-01255-7

Measurement invariance testing of the patient health questionnaire-9 (PHQ-9) across people with and without diabetes mellitus from the NHANES, EMHS and UK Biobank datasets

Autorzy: Arie Nouwen, Sonya S.Deschênes, Zhanna Balkhiyarova, Juan R.Albertorio-Díaz, Inga Prokopenko, Norbert Schmitz
Opublikowane w: Journal of Affective Disorders, Numer 292, 2021, Strona(/y) 311-318, ISSN 0165-0327
Wydawca: Elsevier BV
DOI: 10.1016/j.jad.2021.05.031

Ultra-processed foods, adiposity and risk of head and neck cancer and oesophageal adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition study: a mediation analysis

Autorzy: Fernanda Morales-Berstein, Carine Biessy, Vivian Viallon, Ana Goncalves-Soares, Corinne Casagrande, Bertrand Hémon, Nathalie Kliemann, Manon Cairat, Jessica Blanco Lopez, Aline Al Nahas, Kiara Chang, Eszter Vamos, Fernanda Rauber, Renata Bertazzi Levy, Diana Barbosa Cunha, Paula Jakszyn, Pietro Ferrari, Paolo Vineis, Giovanna Masala, Alberto Catalano, Emily Sonestedt, Yan Borné, Verena Katzke, R
Opublikowane w: European Journal of Nutrition, Numer 63, 2023, Strona(/y) 377-396, ISSN 1436-6207
Wydawca: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00394-023-03270-1

Animal and plant protein intake during infancy and childhood DNA methylation: a meta-analysis in the NutriPROGRAM consortium

Autorzy: Mohammed El Sharkawy,Janine F. Felix,Veit Grote,Trudy Voortman,Vincent W. V. Jaddoe,Berthold Koletzko &Leanne K. Küpers
Opublikowane w: Epigenetics, 2024, ISSN 1559-2308
Wydawca: Taylor & Francis
DOI: 10.1080/15592294.2023.2299045

52-year follow-up of a birth cohort reveals a high pneumonia incidence among young men

Autorzy: Pia Holma, Paula Pesonen, Olli Mustonen, Marjo-Riitta Järvelin, Heikki Kauma, Juha Auvinen, Timo Hautala
Opublikowane w: ERJ Open Research, Numer 8, 2025, Strona(/y) 00707-2021, ISSN 2312-0541
Wydawca: European Respiratory Society (ERS)
DOI: 10.1183/23120541.00707-2021

Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes

Autorzy: Natalia Pervjakova; Gunn-Helen Moen; Maria-Carolina Borges; Teresa Ferreira; James P Cook; Catherine Allard; Robin N Beaumont; Mickaël Canouil; Gad Hatem; Anni Heiskala; Anni Joensuu; Ville Karhunen; Soo Heon Kwak; Frederick T J Lin; Jun Liu; Sheryl Rifas-Shiman; Claudia H Tam; Wing Hung Tam; Gudmar Thorleifsson; Toby Andrew; Juha Auvinen; Bishwajit Bhowmik; Amélie Bonnefond; Fabien Delahaye; Ay
Opublikowane w: Human Molecular Genetics, Numer 31(19), 2022, Strona(/y) 3377-3391, ISSN 0964-6906
Wydawca: Oxford University Press
DOI: 10.1093/hmg/ddac050

Automated calibration of consensus weighted distance-based clustering approaches using sharp

Autorzy: Barbara Bodinier, Dragana Vuckovic, Sabrina Rodrigues, Sarah Filippi, Julien Chiquet, Marc Chadeau-Hyam
Opublikowane w: Bioinformatics, Numer 39(11), 2023, ISSN 1367-4811
Wydawca: Oxford University Press
DOI: 10.1093/bioinformatics/btad635

Green spaces and respiratory, cardiometabolic, and neurodevelopmental outcomes: An individual-participant data meta-analysis of >35.000 European children

Autorzy: Amanda Fernandes, Demetris Avraam, Tim Cadman, Payam Dadvand, Mònica Guxens, Anne-Claire Binter, Angela Pinot de Moira, Mark Nieuwenhuijsen, Liesbeth Duijts, Jordi Julvez, Montserrat De Castro, Serena Fossati, Sandra Márquez, Tanja Vrijkotte, Ahmed Elhakeem, Rosemary McEachan, Tiffany Yang, Marie Pedersen, Johan Vinther, Johanna Lepeule, Martine Vrijheid
Opublikowane w: Environment International, Numer 190, 2024, ISSN 0160-4120
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2024.108853

Cord blood leptin level and a common variant of its receptor as determinants of the BMI trajectory: the EDEN mother-child cohort

Autorzy: Aminata H. Cissé, Marion Taine, Muriel Tafflet, Blandine de Lauzon-Guillain, Karine Clément, Olfa Khalfallah, Laetitia Davidovic, Sandrine Lioret, Marie A. Charles, Barbara Heude
Opublikowane w: Pediatric Obesity, 2022, ISSN 2047-6310
Wydawca: Wiley-Blackwell for the International Association for the Study of Obesity
DOI: 10.1111/ijpo.12955

Investigating childhood maltreatment as a modifier of genetic risk for cardiovascular diseases in the UK Biobank

Autorzy: Helena Urquijo, Ana Gonçalves Soares, Abigail Fraser, Laura D. Howe, Alice R. Carter
Opublikowane w: PLOS One, 2023, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0285258

Examining associations of air pollution and green space with depressive symptoms in adults: A LongITools cross-cohort analysis

Autorzy: Irina Motoc, Bigina N.R. Ginos, Ana Goncalves Soares, Ahmed Elhakeem, Trudy Voortman, Maryam Kavousi, Annemarie I. Luik, Tessa J. Roseboom, Susanne R. de Rooij
Opublikowane w: Environmental Research, Numer 264, 2025, Strona(/y) 120321, ISSN 0013-9351
Wydawca: Academic Press
DOI: 10.1016/j.envres.2024.120321

Associations of low levels of air pollution with cardiometabolic outcomes and the role of diet quality in individuals with obesity

Autorzy: Healy, Darren R; Kårlund, Anna; Mikkonen, Santtu; Puhakka, Soile; Karhunen, Leila; Kolehmainen, Marjukka
Opublikowane w: Environmental Research, Numer 242, 2024, Strona(/y) 117637, ISSN 0013-9351
Wydawca: Academic Press
DOI: 10.1016/j.envres.2023.117637

Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

Autorzy: Thomas W. Winkler*, Humaira Rasheed, Lifelines Cohort Study, DiscovEHR/MyCode study, VA Million Veteran Program, Alexander Teumer, Mathias Gorski, Bryce X. Rowan, Kira J. Stanzick, Laurent F. Thomas, Adrienne Tin, Anselm Hoppmann, Audrey Y. Chu, Bamidele Tayo, Chris H.L. Thio, Daniele Cusi, Jin Fang Chai, Karsten B. Sieber, Katrin Horn, Man Li, Markus Scholz, Massimiliano Cocca, Matthias Wuttke, P
Opublikowane w: Communications Biology, Numer 5(580), 2022, ISSN 2399-3642
Wydawca: Springer Nature
DOI: 10.1038/s42003-022-03448-z

Maternal caffeine consumption during pregnancy and offspring cord blood DNA methylation: an epigenome-wide association study meta-analysis

Autorzy: Laura Schellhas*, Giulietta S. Monasso, Janine F. Felix, Vincent Wv Jaddoe, Peiyuan Huang, Sílvia Fernández-Barrés, Martine Vrijheid, Giancarlo Pesce, Isabella Annesi-Maesano, Christian M. Page, Anne Lise Brantsæter, Mona Bekkhus, Siri E. Håberg, Stephanie J. London, Marcus R. Munafò, Luisa Zuccolo, Gemma C. Sharp
Opublikowane w: Epigenomics, Numer 15(22), 2023, ISSN 1750-1911
Wydawca: Future Medicine Ltd.
DOI: 10.2217/epi-2023-0263

Maternal Mediterranean diet in pregnancy and newborn DNA methylation: a meta-analysis in the PACE Consortium

Autorzy: Leanne K. Küpers; Sílvia Fernández-Barrés; Aayah Nounu; Chloe Friedman; Ruby Fore; Giulia Mancano; Dana Dabelea; Sheryl L. Rifas-Shiman; Rosa H. Mulder; Emily Oken; Laura Johnson; Mariona Bustamante; Vincent W.V. Jaddoe; Marie-France Hivert; Anne P. Starling; Jeanne H.M. de Vries; Gemma C. Sharp; Martine Vrijheid; Janine F. Felix
Opublikowane w: Epigenetics, 2022, Strona(/y) 1-13, ISSN 1559-2308
Wydawca: Taylor & Francis Group
DOI: 10.1080/15592294.2022.2038412

Prenatal Urban Environment and Blood Pressure Trajectories From Childhood to Early Adulthood

Autorzy: Ana Gonçalves Soares, Susana Santos, Emie Seyve, Rozenn Nedelec, Soile Puhakka, Aino-Maija Eloranta, Santtu Mikkonen, Wen Lun Yuan, Deborah A Lawlor, Jon Heron, Martine Vrijheid, Johanna Lepeule, Mark Nieuwenhuijsen, Serena Fossati, Vincent W V Jaddoe, Timo Lakka, Sylvain Sebert, Barbara Heude, Janine F Felix, Ahmed Elhakeem, Nicholas J Timpson
Opublikowane w: JACC: Advances, Numer 3(2), 2024, Strona(/y) 100808, ISSN 2772-963X
Wydawca: Elsevier B.V
DOI: 10.1101/2023.03.31.23288002

A bidirectional Mendelian randomisation study to evaluate the relationship between body constitution and hearing loss

Autorzy: Yiyan He; Ville Karhunen; Anna Pulakka; Marko Kantomaa; Sylvain Sebert
Opublikowane w: Scientific Reports, Numer 13(1), 2023, Strona(/y) 1-10, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-023-44735-x

Epigenetic signature of very low birth weight in young adult life

Autorzy: Juho Kuula, Darina Czamara, Helena Hauta-alus, Jari Lahti, Petteri Hovi, Maija E. Miettinen, Justiina Ronkainen, Johan G. Eriksson, Sture Andersson, Marjo-Riitta Järvelin, Sylvain Sebert, Katri Räikkönen, Elisabeth B. Binder, Eero Kajantie
Opublikowane w: Pediatric Research, 2024, ISSN 0031-3998
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1038/s41390-024-03354-6

comorbidPGS: an R package assessing shared predisposition between Phenotypes using Polygenic Scores

Autorzy: Vincent Pascat, Liudmila Zudina, Anna Ulrich, Jared G. Maina, Marika Kaakinen, Igor Pupko, Amélie Bonnefond, Ayşe Demirkan, Zhanna Balkhiyarova, Philippe Froguel, Inga Prokopenko
Opublikowane w: Human Heredity, Numer 89(1), 2024, Strona(/y) 60-70, ISSN 0001-5652
Wydawca: S. Karger AG
DOI: 10.1159/000539325

Paternal body mass index and offspring DNA methylation: findings from the PACE consortium

Autorzy: Gemma C Sharp, Rossella Alfano, Akram Ghantous, Jose Urquiza, Sheryl L Rifas-Shiman, Christian M Page, Jianping Jin, Silvia Fernández-Barrés, Gillian Santorelli, Gwen Tindula, Gemma C Sharp, Rossella Alfano, Akram Ghantous, Jose Urquiza, Sheryl L Rifas-Shiman, Christian M Page, Jianping Jin, Silvia Fernández-Barrés, Gillian Santorelli, Gwen Tindula, Paul Yousefi, Leanne Kupers, Carlos Ruiz-Are
Opublikowane w: International Journal of Epidemiology, 2021, ISSN 0300-5771
Wydawca: Oxford University Press
DOI: 10.1093/ije/dyaa267

Abdominal obesity is a more important causal risk factor for pancreatic cancer than overall obesity

Autorzy: Jared G. Maina; Vincent Pascat; Liudmila Zudina; Anna Ulrich; Igor Pupko; Amélie Bonnefond; Zhanna Balkhiyarova; Marika Kaakinen; Philippe Froguel; Inga Prokopenko
Opublikowane w: European Journal of Human Genetics, Numer 31, 2023, Strona(/y) 962-966, ISSN 1018-4813
Wydawca: Natue Publishing Group
DOI: 10.1038/s41431-023-01301-3

The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice

Autorzy: Francesca Forzano, Olga Antonova, Angus Clarke, Guido de Wert, Sabine Hentze, Yalda Jamshidi, Yves Moreau, Markus Perola, Inga Prokopenko, Andrew Read, Alexandre Reymond, Vigdis Stefansdottir, Carla van El & Maurizio Genuardi, on behalf of the Executive Committee of the European Society of Human Genetics & the Public and Professional Policy Committee of the European Society of Human Genetics
Opublikowane w: The European Journal of Human Genetics, 2021, ISSN 1018-4813
Wydawca: Natue Publishing Group
DOI: 10.1038/s41431-021-01000-x

Post-weight loss changes in fasting appetite- and energy balance-related hormone concentrations and the effect of the macronutrient content of a weight maintenance diet: a randomised controlled trial

Autorzy: Mari Näätänen, Marjukka Kolehmainen, David E. Laaksonen, Karl-Heinz Herzig, Kaisa Poutanen, Leila Karhunen
Opublikowane w: European Journal of Nutrition, 2020, ISSN 1436-6207
Wydawca: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00394-020-02438-3

Determinants of body mass index during early life: findings from an exposome-wide association study with follow-up replication and Mendelian randomization analyses

Autorzy: Jie V Zhao, Ana Goncalves Soares, Demetris Avraam, Tim Cadman, Marie Aline Charles, Barbara Heude, Vincent Jaddoe, Yannis Manios, George Moschonis, Anne-Marie Nybo Andersen, Lorenzo Richiardi, Justiina Ronkainen, Sylvain Sebert, Morris Swertz, Evangelia Tzorovili, Martine Vrijheid, Wen Lun Yuan, Deborah A Lawlor, Ahmed Elhakeem
Opublikowane w: Exposome, Numer 5, 2025, ISSN 2635-2265
Wydawca: Oxford University Press (OUP)
DOI: 10.1093/exposome/osaf004

Metabolic profiles reflect weight loss maintenance and the composition of diet after very-low-energy diet

Autorzy: Mari Näätänen; Anna Kårlund; Santtu Mikkonen; Anton Klåvus; Otto Savolainen; Marko Lehtonen; Leila Karhunen; Kati Hanhineva; Marjukka Kolehmainen
Opublikowane w: Clinical Nutrition, Numer 42(7), 2023, Strona(/y) 1126-1141, ISSN 0261-5614
Wydawca: Churchill Livingstone
DOI: 10.1016/j.clnu.2023.05.011

Maternal plasma fatty acid patterns in mid-pregnancy and offspring epigenetic gestational age at birth

Autorzy: Giulietta S. Monasso, Trudy Voortman, Janine F. Felix
Opublikowane w: Epigenetics, 2022, ISSN 1559-2294
Wydawca: Landes Bioscience
DOI: 10.1080/15592294.2022.2076051

Cohort profile:46 years of follow-up of the Northern Finland Birth Cohort 1966 (NFBC1966)

Autorzy: Nordström, T. (Tanja); Miettunen, J. (Jouko); Auvinen, J. (Juha); Ala-Mursula, L. (Leena); Keinänen-Kiukaanniemi, S. (Sirkka); Veijola, J. (Juha); Järvelin, M.-R. (Marjo-Riitta); Sebert, S. (Sylvain); Männikkö, M. (Minna)
Opublikowane w: International Journal of Epidemiology, Numer 50(6), 2021, Strona(/y) 1786-1787, ISSN 0300-5771
Wydawca: Oxford University Press
DOI: 10.1093/ije/dyab109

Cardiometabolic Risk Estimation Using Exposome Data and Machine Learning

Autorzy: Angélica Atehortúa; Polyxeni Gkontra; Marina Camacho; Oliver Diaz; Maria Bulgheroni; Valentina Simonetti; Marc Chadeau-Hyam; Janine F. Felix; Sylvain Sebert; Karim Lekadir
Opublikowane w: International Journal of Medical Informatics, Numer 179, 2023, ISSN 1386-5056
Wydawca: Elsevier BV
DOI: 10.2139/ssrn.4367352

Tissue-wide metabolomics reveals wide impact of gut microbiota on mice metabolite composition

Autorzy: Iman Zarei, Ville M. Koistinen, Marietta Kokla, Anton Klåvus, Ambrin Farizah Babu, Marko Lehtonen, Seppo Auriola & Kati Hanhineva
Opublikowane w: Scientific Reports, Numer 12, 2022, Strona(/y) 15018, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-022-19327-w

Identification and distribution of sterols, bile acids, and acylcarnitines by LC-MS/MS in humans, mice, and pigs – A qualitative analysis

Autorzy: Ambrin Farizah Babu, Ville Mikael Koistinen, Soile Turunen, Gloria Solano-Aguilar, Joseph F. Urban, Jr., Iman Zarei and Kati Hanhineva
Opublikowane w: Metabolites, Numer 12(1), 2022, Strona(/y) 49, ISSN 2218-1989
Wydawca: MDPI
DOI: 10.3390/metabo12010049

Maternal iron status in early pregnancy and DNA methylation in offspring: an epigenome-wide meta-analysis

Autorzy: M. J. Taeubert, P. de Prado-Bert, M. L. Geurtsen, G. Mancano, M. J. Vermeulen, I. K. M. Reiss, D. Caramaschi, J. Sunyer, G. C. Sharp, J. Julvez, M. U. Muckenthaler & J. F. Felix
Opublikowane w: Clinical Epigenetics, Numer 14(59), 2022, ISSN 1868-7083
Wydawca: BioMed Central
DOI: 10.1186/s13148-022-01276-w

Association of Exposure to Second-Hand Smoke During Childhood with Blood DNA Methylation

Autorzy: Marta Cosin-Tomas, Thanh Hoang, Cancan Qi, Giulietta S. Monasso, Ryan Langdon, Simon Kebede Meri, Lucinda Calas, Paula de Prado-Bert, Rebecca C. Richmond, Vincent W.V. Jaddoe, Liesbeth Duijts, John Wright, Isabella Annesi-Maesano, Regina Gražulevičienė, Marianna Karachaliou, Gerard Koppelman, Erik Melén, Olena Gruzieva, Martine Virjheid, Paul D. Yousefi, Janine F. Felix, Stephanie J. Londo
Opublikowane w: Environmental Epigenetics, 2024, ISSN 2058-5888
Wydawca: Oxford University Press
DOI: 10.2139/ssrn.4944259

Timing based clustering of childhood BMI trajectories reveals differential maturational patterns; Study in the Northern Finland Birth Cohorts 1966 and 1986

Autorzy: Anni Heiskala, J. Derek Tucker, Priyanka Choudhary, Rozenn Nedelec, Justiina Ronkainen, Olli Sarala, Marjo-Riitta Järvelin, Mikko J. Sillanpää, Sylvain Sebert
Opublikowane w: International Journal of Obesity, Numer 49, 2025, Strona(/y) 872-880, ISSN 0307-0565
Wydawca: Nature Publishing Group
DOI: 10.1038/s41366-025-01714-8

Heterogeneous Effects of Calorie Content and Nutritional Components Underlie Dietary Influence on Pancreatic Cancer Susceptibility

Autorzy: James Dooley, Vasiliki Lagou, Jermaine Goveia, Anna Ulrich, Katerina Rohlenova, Nathalie Heirman, Tobias Karakach, Yulia Lampi, Shawez Khan, Jun Wang, Tom Dresselaers, Uwe Himmelreich, Marc J. Gunter, Inga Prokopenko, Peter Carmeliet, Adrian Liston
Opublikowane w: Cell Reports, Numer 32/2, 2020, Strona(/y) 107880, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2020.107880

Women exposed to famine in early gestation have increased mortality up to age 76 years

Autorzy: Aline Marileen Wiegersma, Tessa J. Roseboom, Susanne R. de Rooij
Opublikowane w: Paediatric and Perinatal Epidemiology, Numer 39, 2025, Strona(/y) 236-241, ISSN 0269-5022
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/ppe.13131

MOLGENIS Armadillo: a lightweight server for federated analysis using DataSHIELD

Autorzy: Tim Cadman, Mariska K Slofstra, Marije A van der Geest, Demetris Avraam, Tom R P Bishop, Tommy de Boer, Liesbeth Duijts, Sido Haakma, Eleanor Hyde, Vincent Jaddoe, Tarik Karramass, Fleur Kelpin, Yannick Marcon, Angela Pinot de Moira, Dick Postma, Clemens Tolboom, Ruben L Veenstra, Stuart Wheater, Marieke Welten, Rebecca C Wilson, Erik Zwart, Morris Swertz
Opublikowane w: Bioinformatics, Numer 41, 2025, ISSN 1367-4811
Wydawca: Oxford University Press (OUP)
DOI: 10.1093/bioinformatics/btae726

A framework for conducting GWAS using repeated measures data with an application to childhood BMI

Autorzy: Kimberley Burrows, Anni Heiskala, Jonathan P. Bradfield, Zhanna Balkhiyarova, Lijiao Ning, Mathilde Boissel, Yee-Ming Chan, Philippe Froguel, Amelie Bonnefond, Hakon Hakonarson, Alexessander Couto Alves, Deborah A. Lawlor, Marika Kaakinen, Marjo-Riitta Järvelin, Struan F. A. Grant, Kate Tilling, Inga Prokopenko, Sylvain Sebert, Mickaël Canouil, Nicole M. Warrington
Opublikowane w: Nature Communications, Numer 15, 2024, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-024-53687-3

Design and Implementation of a National SARS-CoV-2 Monitoring Program in England: REACT-1 Study

Autorzy: Paul Elliott, Matthew Whitaker, David Tang, Oliver Eales, Nicholas Steyn, Barbara Bodinier, Haowei Wang, Joshua Elliott, Christina Atchison, Deborah Ashby, Wendy Barclay, Graham Taylor, Ara Darzi, Graham S. Cooke, Helen Ward, Christl A. Donnelly, Steven Riley, Marc Chadeau-Hyam
Opublikowane w: American Journal of Public Health, Numer 113, 2023, Strona(/y) 545-554, ISSN 0090-0036
Wydawca: American Public Health Association
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Epigenome-wide contributions to individual differences in childhood phenotypes: a GREML approach

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Exposure to the Dutch Famine in Early Gestation and Cognitive Function and Decline in Older Age

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Lessons learned from 25 Years of Research into Long term Consequences of Prenatal Exposure to the Dutch famine 1944–45: The Dutch famine Birth Cohort

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