THERVACB: A THERAPEUTIC VACCINE TO CURE HEPATITIS B

Informacje na temat projektu

TherVacB

Identyfikator umowy o grant: 848223

DOI

10.3030/848223

Data podpisania przez KE 6 Grudnia 2019

Data rozpoczęcia 1 Stycznia 2020

Data zakończenia 31 Grudnia 2026

Finansowanie w ramach

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Koszt całkowity

€ 10 425 686,21

Wkład UE

€ 10 425 686,21

Koordynowany przez

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Germany

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (4)

Synopsis and protocol of the patient registry

In close cooperation with all WP partners MHH will provide a short protocol as well as the study synopsis of the patient registry.

Cross-network SOPs for immunoassays

SOPs for centralized and decentralized immunoassays available and in place; initial cross-validation of decentralized immunoassays to ensure inter-lab precision finished

Agreement of sample storage

HMGU will provide an informed consent form and an SOPs for sample preparation and storage (plasma and PBMCs) for all participating centers

Incidental Findings Policy

Report on the Incidental Findings Policy

Websites, patent fillings, videos etc. (1)

THERVACB web site and the relevant social media

Overview of the objectives of the THERVACB public website as part of the dissemination strategy, and its main functionalities, as well as an outline of the THERVACB social media strategy.

Publikacje

Peer reviewed articles (11)

Perceptions of Stigma Among Patients With Hepatitis B in Germany: Cross-Sectional Survey

Autorzy: Bettina M Zimmermann, Theresa Willem, Michael Rost, Nina Matthes, Alena Buyx
Opublikowane w: JMIR Formative Research, Numer 9, 2025, Strona(/y) e66379-e66379, ISSN 2561-326X
Wydawca: JMIR Publications Inc.
DOI: 10.2196/66379

Social Media Recruitment as a Potential Trigger for Vulnerability: Multistakeholder Interview Study

Autorzy: Nina Matthes, Theresa Willem, Alena Buyx, Bettina M Zimmermann
Opublikowane w: JMIR Human Factors, Numer 11, 2024, Strona(/y) e52448-e52448, ISSN 2292-9495
Wydawca: JMIR Human Factors
DOI: 10.2196/52448

PD-L1 Silencing in Liver Using siRNAs Enhances Efficacy of Therapeutic Vaccination for Chronic Hepatitis B

Autorzy: Till Bunse, Anna D Kosinska, Thomas Michler, Ulrike Protzer
Opublikowane w: Biomolecules, Numer 12(3):470, 2022, ISSN 2218-273X
Wydawca: MDPI Open Access Journals
DOI: 10.3390/biom12030470

Practical Benefits, Challenges, and Recommendations on Social Media Recruitment: Multi-Stakeholder Interview Study

Autorzy: Goldman N, Willem T, Buyx A, Zimmermann B
Opublikowane w: Journal of Medical Internet Research, Numer 25:e44587, 2023, ISSN 1438-8871
Wydawca: Journal of medical Internet Research
DOI: 10.2196/44587

Acceptance of Social Media Recruitment for Clinical Studies Among Patients With Hepatitis B: Mixed Methods Study

Autorzy: Theresa Willem, Bettina M Zimmermann, Nina Matthes, Michael Rost, Alena Buyx
Opublikowane w: Journal of Medical Internet Research, Numer 26, 2024, Strona(/y) e54034, ISSN 1438-8871
Wydawca: Journal of medical Internet Research
DOI: 10.2196/54034

Social media advertising for clinical studies: Ethical and data protection implications of online targeting

Autorzy: Rainer Mühlhoff, Theresa Willem
Opublikowane w: Big Data & Society, Numer 10, 2023, Strona(/y) 205395172311561, ISSN 2053-9517
Wydawca: SAGE
DOI: 10.1177/20539517231156127

Ethical Issues in Social Media Recruitment for Clinical Studies: Ethical Analysis and Framework

Autorzy: Zimmermann BM, Willem T, Bredthauer CJ, Buyx A
Opublikowane w: J Med Internet Res, Numer 24 (5), 2022, ISSN 1438-8871
Wydawca: Journal of medical Internet Research
DOI: 10.2196/31231

Correction: Ethical Issues in Social Media Recruitment for Clinical Studies: Ethical Analysis and Framework

Autorzy: Bettina M Zimmermann; Theresa Willem; Carl Justus Bredthauer; Alena Buyx
Opublikowane w: J Med Internet Res, 2022, ISSN 1438-8871
Wydawca: Journal of medical Internet Research
DOI: 10.2196/40848

Immunogenicity and Antiviral Response of Therapeutic Hepatitis B Vaccination in a Mouse Model of HBeAg-Negative, Persistent HBV Infection

Autorzy: Kosinska, A.D.; Festag, J.; Mück-Häusl, M.; Festag, M.M.; Asen, T.; Protzer, U.
Opublikowane w: Vaccines, Numer 9(8), 841, 2021, ISSN 2076-393X
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines9080841

Activation of CD4 T cells during prime immunization determines the success of a therapeutic hepatitis B vaccine in HBV-carrier mouse models

Autorzy: Jinpeng Su, Livia Brunner, Edanur Ates Oz, Julia Sacherl, Geraldine Frank, Helene Anne Kerth, Frank Thiele, Marian Wiegand, Carolin Mogler, Julio Cesar Aguilar, Percy A. Knolle, Nicolas Collin, Anna D. Kosinska, Ulrike Protzer
Opublikowane w: Journal of Hepatology, 2023, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/j.jhep.2022.12.013

Evaluation of the Effect of CD70 Co-Expression on CD8 T Cell Response in Protein-Prime MVA-Boost Vaccination in Mice

Autorzy: Ann-Sophie Stephan; Anna D. Kosinska; Martin Mück-Häusl; Andreas Muschaweckh; Clemens Jäger; Natalie Röder; Mathias Heikenwälder; Claudia Dembek; Ulrike Protzer
Opublikowane w: Volume 11, Numer 1, 2023, ISSN 2076-393X
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines11020245